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TBA Plus d'infos... Tags: Bastien, Renaud, Draft:Toopy and Binoo: The Movie, Draft:Vacation with Derek Annonce publiée le 17-01-2026 |
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| Laboratoire Jean Perrin Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 |
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Invite par: Institut Necker Enfants Malades - Auditorium 1
Revealing cellular programs that shape successful immune activation.After completing my PhD at the Institute of Molecular Pathology (IMP) in Vienna, I pursued a short postdoctoral stay at the Centre for Genomic Regulation (CRG) in Barcelona before joining the laboratory of Michael Sixt at the Institute of Science and Technology Austria (ISTA) in Klosterneuburg. In 2017, I was awarded the NNF Young Investigator Award and funding through the Returning Experts Program of North Rhine-Westphalia, which enabled me to establish my independent research group at the University of Bonn in 2018. Since then, my lab has focused on elucidating cellular programs that govern effective immune activation, with particular emphasis on cytoskeletal dynamics. In 2025, I was appointed Full Professor at the University of Erlangen, and my group is currently transitioning from the LIMES Institute to the Medical Faculty in Erlangen. Mark your calendars and make sure to join!
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Tags: Institute of Science and Technology Austria, University of ErlangenNuremberg
Annonce publiée le 16-01-2026
Institut Necker Enfants Malades
Eva Kiermaier -
Invite par: Anna Sartori-Rupp
WANDA KUKULSKI University of Bern, Institute of Biochemistry and Molecular Medicine External attendees wishing to participate in the seminar are required to contact the following email address in order to obtain access to the Institut ...
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Tags: Programmed cell death, Apoptosis, Cellular senescence, Cell signaling, Immunology, APAF1
Annonce publiée le 16-01-2026
Institut Pasteur
Batiment Monod Building, salle Agnes Ullmann Auditorium, -
Invite par: Paris Postdoc Seminar (PPS)
Plus d'infos...
Tags: Integral membrane proteins, Lipids, Sphingosine N-acyltransferase, Ceramide, Heterotopia, Cerebral cortex, Gray matter heterotopia, Lipid signaling
Annonce publiée le 16-01-2026
IBENS
salle Favard, IBENS 46 rue d'Ulm 75005 Paris -
Invite par: Institut Necker Enfants Malades - Room 4, Floor -1
Investigating Hematopoiesis and Erythropoiesis in Sickle Cell DiseaseMaria is a postdoctoral researcher at tthe Laboratory of Molecular Mechanisms of Hematological Disorders and Therapeutic Implications at Institut Imagine (INSERM U1163), led by Professor Olivier Hermine and supervised by Dr. Sara El Hoss and Dr. Thiago Trovati Maciel. Her field of work has been strongly associated with sickle cell disease, and she has acquired expertise in red blood cell biology, hematopoietic stem cell research, and gene therapy through international research experiences. Her current work investigates the role of inflammation in sickle cell disease, aiming to better understand how inflammatory processes influence hematopoiesis, disease severity, and pregnancy.Please join us to discuss and exchange ideas regarding Maria Image
Plus d'infos...
Tags: Blood, Health in Africa, Hematopoiesis, Histology, Sickle cell disease, Haematopoiesis, Blood cell, Hematology
Annonce publiée le 16-01-2026
Institut Necker Enfants Malades
Maria Lizarralde-Iragorri -
La semaine prochaine, Seema Grewal, redactrice en chef deJournal of Cell Science presentera le seminaire : The Future of Publishing Resume : The publishing landscape is constantly evolving, being reshaped by new technologies, open science movements and changing incentives in academia. This talk will delve behind the scenes of publishing at the Journal of Cell Science, highlighting how to prepare an article and navigate the submission and peer review process. We will also explore emerging trends and challenges, such as the rise of preprints, experiments with peer review, alternative publishing models and the use of AI, as well as careers in the publishing industry.
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Tags: Academic publishing, Metascience, Open science, Data publishing, Open access, Preprint, Seema, Peer review
Annonce publiée le 16-01-2026
Institut Jacques Monod
Institut Jacques Monod Salle Francois Jacob, 15 rue Helene Brion, Paris, France -
Invite par: Thibaut Brunet
Abstract: How do animals build, modify, and restore their shape? Shape is an organism-scale property that emerges from distributed molecular and biophysical processes coordinated across time and space, making causality inherently cross-scale. In this ...
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Tags: European Molecular Biology Laboratory, Heidelberg, Cnidaria
Annonce publiée le 16-01-2026
Institut Pasteur
Batiment Monod, salle Amphi Ullmann, -
Complement-Driven Tumor ControlA small symposium will take place on Monday, January 26, from 11:00 am to 12:30 pm, in the Gustave Roussy Auditorium. Two presentations will be given by invited speakers from Lund University (Sweden):A Novel Anti-Cancer Vaccine Strategy for Enhancing T-Cell Immunity through Dendritic Cell Targeting Prof. Kristian RiesbeckSUMMARY : Despite advances in cancer immunotherapy, more than half of patients fail to respond adequately, highlighting the need for improved vaccine strategies. Lipid nanoparticle (LNP)-based mRNA vaccines efficiently deliver antigens but lack specificity for antigen-presenting cells. This project addresses this limitation by targeting LNPs to the pattern recognition receptor Dectin-1 on dendritic cells. We have discovered novel protein ligands that activate Dectin-1 and function as potent adjuvants when coupled to mRNA-LNPs encoding cancer neoantigens. These interactions promote efficient T-cell cross-priming and robust cytotoxic T-cell responses. Using interdisciplinary approaches, we are now evaluating these proteins in tumour models to establish a platform for developing more effective cancer vaccines.
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Tags: Immunology, Cancer vaccines, Virology, Cancer immunotherapy, Biotechnology, Immunotherapy, MRNA vaccine, Cross-presentation, Cancer vaccine, Lipid-based nanoparticle, Dendritic cell, Vaccine
Annonce publiée le 16-01-2026
Centre de Recherche des Cordeliers -
TBA
Plus d'infos...
Tags: Draft:Toopy and Binoo: The Movie, Draft:Vacation with Derek
Annonce publiée le 15-01-2026
Laboratoire Jean Perrin
Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 -
TBA
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Tags: Mont Charvin
Annonce publiée le 15-01-2026
Laboratoire Jean Perrin
Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 -
Invite par: Anna Sartori-Rupp
WANDA KUKULSKI University of Bern, Institute of Biochemistry andMolecular Medicine ABSTRACT The cell death program known as apoptosis is essential for organisms to remove surplus cells. This mechanism is important during development as well ...
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Tags: Programmed cell death, Cellular senescence, Apoptosis, Cell signaling, Immunology, APAF1, Apoptosome
Annonce publiée le 15-01-2026
Institut Pasteur
Batiment: Monod Building Salle: Agnes Ullmann Auditorium -
8th Advanced Course on Tissue Immunity - Immune cells in development, homeostasis, aging and pathology is a 4-day program focused on the role of immune cells in tissue development, homeostasis, aging, and pathologies such as cancer. It includes lectures, poster sessions, workshops, and networking activities, offering Master's, PhD students, and postdocs from Latin America the opportunity to engage with leading experts. Travel grants are available for selected participants. The 8th Advanced Course on Tissue Immunity - Immune cells in development, homeostasis, aging and pathology? offers four days of lectures and discussions focused on the immune and non-immune functions of tissue-resident immune cells, their roles in development and homeostasis, and their dysregulation during aging and disease, including cancer. Leading experts in immunology will present the latest research on tissue development and immunity, inflammation, tissue-pathogen interactions, aging, pathological processes, and current challenges and opportunities in cancer immunotherapy. In addition to the lectures, participants will have the chance to present their projects during poster sessions, engage directly with speakers through scientific speed-dating sessions, and take part in workshops on career opportunities, accessibility in science, project design, and the importance of studying both male and female tissue immunity. This advanced course is open to Master's students, PhD candidates, and postdoctoral researchers from Latin America and other countries. As part of an international cooperation project between France and Chile,the organizers will provide up to 10 travel grants for participants from other Latin American countries and different regions of Chile.
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Tags: Immunology, Inflammation, Immunity, Pathology, Immune system
Annonce publiée le 15-01-2026
Institut Curie
Webinar -
Mammalian cells leverage collective behaviors to coordinate movement, force production, and fluid pumping during a range of crucial biological processes. These collective behaviors are essential for establishing and maintaining homeostasis and require constitutive cells to accurately sense and respond to their environment. Whereas these collective behaviors are relatively well-studied in the context of confined and freely migrating mature epithelia, it remains poorly understood how they are modulated by exogenous cues. The work presented addresses this gap in knowledge by directly measuring collective behaviors in exogenously controlled epithelial tissues. First, we present data showing that short-term bioelectric stimulation of an epithelium has long-lasting effects on collective migration in the system. We explore the spatiotemporal dynamics of migrational speed, alignment, and correlation in distinct regions of the tissue before, during, and after bioelectric stimulation. These data show that epithelia exhibit an inhomogeneous response to a homogeneous cue. We then show that bioelectric stimulation can be used in a 3D context to control fluid pumping and migration in a lab-grown kidney model via a process we call ?electro-inflation'. We performed inhibition assays and developed a continuum model to show that electro-inflation is driven by ion crowding and mediated by a balance between ion channel activity and cytoskeletal mechanics. We then generalize our study of collective behavior to exogenous cues outside of bioelectricity by presenting a bioengineered system wherein cells are forced to adhere to their substrate via cadherins - a family of proteins used exclusively in cell-cell junctions. We show that this bio-inspired functionalized system directly modulates force propagation, migrational state, and cell-cycling in the epithelium. Finally, we present ongoing work on mapping the spatiotemporal expenditure of mechanical energy in epithelia using a combination of traction force microscopy and modeling. We show that energy expenditure in epithelia is spatiotemporally patterned, scales with tissue size, and actively regulates migration.
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Tags: Biophysics, Developmental bioelectricity, Electricity, Epithelium, Duct
Annonce publiée le 15-01-2026
Institut Curie
Centre de recherche - Paris - Amphitheatre Marie Curie -
During early development, internal cues guide embryonic cells to acquire fate and perform morphogenesis. In nature, embryos develop within particular microenvironments, whose precise roles in regulating embryogenesis remain largely unexplored. In this study, we focus on the microbiological environment that early embryos may encounter, such as the bacteria that can prevalently infect the human uterus. Using zebrafish and mouse models of bacterial infection in early embryos, we show that epithelial cells of the embryonic surface can detect, ingest, and destroy bacteria by activating a distinct immune gene program essential for normal development. Our multi-scale analysis further reveals the cytoskeletal machinery mediating protrusion dynamics for bacterial engulfment. Remarkably, we demonstrate similar phagocytic abilities for clearing bacteria in human embryos. These findings have important implications for understanding the onset of innate immunity and the causes of human developmental failures, which underscore the role of the microenvironment in natural embryogenesis.
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Tags: Danio, Freshwater fish of India, Regenerative biomedicine, Stem cell research, Zebrafish, Innate immune system, Bacteria
Annonce publiée le 15-01-2026
Institut Curie
Centre de recherche - Paris - Amphitheatre Helene Martel-Massignac (BDD) -
Towards detection of enhancer and promoter activities in single cells The majority of disaese-associated genetic variants fall into intergenic, regulatory regions rather than the genes they control. Hence, the path towards identifying the cell types and developmental stages that are altered by genetic variants inevitably leads through locating and quantitatively assessing these regulatory regions and the enhancers and promoters they harbor. However, studying the activity of regulatory regions genome-wide in specific cells has been challenging. State-of-the-art approaches have low sensitivity, require extensive input material, or are limited to cell lines rather than disease-relevant tissue samples. Also, the lack of benchmarks has caused inconsistent accuracy estimates and thus an inability to compare assays and computational methods. To address these issues, we devised a new, combined approach based on the enrichment of nuclear, capped RNAs (nucCAGE) and a light-gradient boosting machine algorithm (PRIMEloci). This allowed to detect transcriptionally active regulatory regions with unmatched sensitivity and to map enhancers and promoters enriched in fine-mapped eQTLs, pathogenic GWAS variants, and CRISPRi loci. Based on the FANTOM5 enhancer atlas, we drastically expanded the landscape of known enhancers, mapped them in a cell type-specific manner and outlined inter-organ mechanisms for genetic variants influencing physiological and disease traits. In parallel, we develop experimental and computational methods to record active regulatory elements over time andin vivoon the level of genomic DNA rather than RNA via DNA adenine methylation identification (DamID). As a first step, we benchmarked all existing software dealing with DamID data. This framework allowed developing the most sensitive model for DamID data analysis and aids ongoing efforts to record enhancer and promoter activities in single cells. Together, our methods aim to link regulatory elements to their cell-type specific biological functions, facilitate variant interpretation and advance insights into gene regulation during development and disease progression.
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Tags: Gene expression, Enhancer, DNA adenine methyltransferase identification, Regulatory sequence, Promoter, Transcription, FANTOM, Regulation of gene expression, STARR-seq, Super-enhancer
Annonce publiée le 15-01-2026
Institut Curie
Centre de recherche - Paris - Amphitheatre Helene Martel-Massignac (BDD) -
Invite par: Arthur Michaut
Monod 7th floor, room 03, 12:00 to 14:00 Artur Ruppel (Etienne-Mannveille lab): Designing minimalistic tissues: a reductionist approach to dissect collective behaviour Enara Larranaga Carricajo (Baroud lab): Strain magnitude’s effect on spheroid mechanics Karine ...
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Annonce publiée le 15-01-2026
Institut Pasteur
Batiment: Monod/66 Salle: 03 7th floor, Monod -
Invite par: Gerard Eberl
Ivaylo Ivanov obtained a B.Sc. in Biotechnology and M.Sc. in Molecular Biology from Sofia University in his native Bulgaria. He obtained his Ph.D. in Cell and Molecular Biology from The University of Alabama at ...
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Tags: Ivaylo Ivanov, Microbiota, Immunology
Annonce publiée le 12-01-2026
Institut Pasteur
Batiment Metchnikoff , salle Jules Bordet Amphitheater, -
Invite par: Sebastian Baumgarten
Abstact : Malaria parasites depend on specialized microtubule-based structures that are critical for their pathogenicity and transmission. In this talk, I will show how expansion microscopy has revolutionized our ability to visualize and analyze these ...
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Tags: Parasitology, Malaria, Disease ecology, Infectious diseases, Ecology, Parasitism, Disease vector, Plasmodium
Annonce publiée le 10-01-2026
Institut Pasteur
Batiment Fernbach , salle Jean-Paul Aubert , -
Invite par: Aude Bernheim
L’Institut Pasteur vous ouvre ses portes et vous invite a une conference scientifique pour le grand public, accompagnee d'une performance artistique ! Pascale Cossart parlera de virus et de bacteries, ces micro-organismes bien differents, ...
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Annonce publiée le 08-01-2026
Institut Pasteur
Batiment: Duclaux Salle: Amphitheatre Duclaux -
Invite par: Yasmine Belkaid
Dr. Emmanuelle Passegue, Ph.D. is the endowed Alumni Professor of Genetics et Development and the Director of the Columbia Stem Cell Initiative (CSCI) at Columbia University Irving Medical Center (CUIMC) in New York City. ...
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Tags: Stem cells, Biotechnology, Cell biology, Cloning, Developmental biology, Hematopoietic stem cell
Annonce publiée le 08-01-2026
Institut Pasteur
Batiment Monod, salle Agnes Ullmann amphitheater , -
Invitee par l’equipe Ribes / Nedelec, Dr Vicki Metzis, head of the Development and Transcriptional Control Group, MRC LMS, Imperial, va presenter un seminaire de l’Institut Jacques Monod sur le theme : Fine-tuning gene expression to build the body plan Resume : Vicki Metzis is a developmental biologist investigating how cells establish and maintain their identity during development. Her lab studies how gene expression dynamics are regulated by cis-regulatory elements and their impact on the variety of cell types that emerge in the developing body plan. A central focus of this work is the transcription factor CDX2, whose transient expression is essential for caudal body formation and Hoxgene patterning. In this seminar, Vicki will present the latest findings from the group revealing regulatory strategies constraining Cdx2, and the broader impact of CDX factors on the developing body plan.
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Tags: Transcription factors, Cdx, Homeobox protein CDX-2, Gene expression, Fine-tuning, Hox gene
Annonce publiée le 07-01-2026
Institut Jacques Monod
Institut Jacques Monod Salle Francois Jacob, 15 rue Helene Brion, Paris, France -
La prochaine reunion du cytoskeleton club aura lieu mercredi 21 janvier a l’Institut Pasteur : Shreyangi CHAKRABORTY (PhD student, C. Janke's team, Institut Curie Orsay) presentera «The role of tubulin polyglutamylation in controlling the microtubule functions in healthy and degenerating neurons Amir KHOSRAVANIZADEH (post-doc, N. Minc's team, IJM) presentera «Agent-based simulations of cytoplasm crowding and viscoelasticity. »
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Tags: Cytoskeleton, Post-translational modification, Protein structure, Tubulin, Microtubule, Polyglutamylation, Cytoplasm, Curie Institute
Annonce publiée le 07-01-2026
Institut Jacques Monod
Insitut Jacques Monod -
Invite par: CIRB-College de France
Plus d'infos...
Annonce publiée le 06-01-2026
College de France
au College de France - Salle D2 - 11 place Marcelin Berthelot - 75005 Paris -
Invite par: CIRB-College de France
Plus d'infos...
Annonce publiée le 06-01-2026
College de France
au College de France Amphi Delmas-Marty - 11 place Marcelin Berthelot - 75005 Paris -
Invite par: CIRB-College de France
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Annonce publiée le 06-01-2026
College de France
au College de France - Salle 2 - 11 place Marcelin Berthelot - 75005 Paris -
Invite par: CIRB-College de France
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Annonce publiée le 06-01-2026
College de France
au College de France - Salle D2 - 11 place Marcelin Berthelot - 75005 Paris -
Invitee par l’equipe Ladoux/Mege, Jennifer Young (Assistant Professor, Biomedical Engineering Department,Principal Investigator, Mechanobiology Institute National University of Singapore) va presenter un seminaire de l’Institut Jacques Monod sur le theme : Biomaterial design for extracellular matrix mechanobiology Resume : Extracellular cues stemming from the matrix dictate a multitude of cellular functions, from motility to stem cell differentiation. Yet, the extracellular environment is inherently complex and thus hinders our understanding of specific matrix-based contributions to cellular behavior. Our work focuses specifically on the context of age-related matrix remodeling and engineering materials capable of recapitulating matrix properties in vitro at both the micro and nano length scales. This talk will highlight some of our material approaches to control cell-matrix interactions in the context of aging and mechanobiology. Our strategies ultimately aim to interrogate the cell-matrix interface using highly defined biomaterial systems that can inform future matrix-based treatment strategies. Jennifer Young was trained as a biomedical engineer at the University of California, San Diego (La Jolla, CA, USA). During her Ph.D. with Prof. Adam Engler, she studied the role of mechanics in cardiac development and created a hydrogel system capable of mimicking dynamic tissue properties in vitro. Inspired by the role of extracellular matrix (ECM) in dictating cell behavior and fate, she joined the Cellular Biophysics group of Prof. Joachim Spatz at the Max Planck Institute for Medical Research (Heidelberg, Germany) to study how nanoscale ECM cues regulate cancer cell function. She established the Soft Nano-Biomaterials Lab in 2021 at the Mechanobiology Institute and Biomedical Engineering Department, National University of Singapore where her work focuses on identifying and mimicking nano-to-microscale matrix properties and unraveling their contributions to cellular behavior.
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Tags: Extracellular matrix, Mechanobiology, Cell culture techniques, Biomedical engineering, Tissue engineering, Wellcome Trust Centre for Cell-Matrix Research
Annonce publiée le 06-01-2026
Institut Jacques Monod
Institut Jacques Monod Salle Francois Jacob, 15 rue Helene Brion, Paris, France -
Endogenous retroviruses (HERVs), the relics of ancient viral integrations are increasingly emerging as active wiring within our genome, functioning as cis-regulatory elements that control nearby immune genes. This seminar will highlight evidence, including from our own lab, that HERVs assemble stress-responsive gene-regulatory networks operating both locally (in cis) and at a distance (in trans) to fine-tune immune activation and inflammatory balance across diverse biological contexts, from placenta to brain to blood. A striking human example comes from HIV elite controllers; a rare group of individuals who suppress HIV without therapy whose CD4 T cells are marked by a distinctive repertoire of transcriptionally active HERVs regulating nearby antiviral factors. Beyond cis regulation, the human genome also retains a reservoir of HERV sequences capable of encoding viral gag and envelope proteins with the power to reshape cellular physiology: some envelopes can protect cells by blocking viral entry, exemplifying viral genes repurposed for host defence, while our data suggest that gag and certain envelopes, reactivated in cancers or during immune activation can perturb distant tissues, including the CNS, forging unexpected connections between cancer progression and neurodegeneration. Together, these findings reveal an underappreciated continuum across immunity, cancer and brain health, where recycled? retroelements can be protective in one context yet pathogenic when mis-expressed in another.
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Tags: Molecular biology, Virology, Retroviridae, Endogenous retrovirus, Non-coding DNA, Retrovirus, Antiviral drug, Group-specific antigen, HIV, Human endogenous retrovirus-W, Intrinsic immunity
Annonce publiée le 06-01-2026
Institut Curie
Centre de recherche - Paris - Amphitheatre Helene Martel-Massignac (BDD) -
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Annonce publiée le 05-01-2026
Inst. Bio. Paris Seine
7-9 quai Saint Bernard, 75005 Paris -
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Annonce publiée le 05-01-2026
Inst. Bio. Paris Seine
7-9 quai Saint Bernard, 75005 Paris -
TBC
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Annonce publiée le 23-12-2025
Institut Curie
Centre de recherche - Paris - Amphitheatre Marie Curie -
Join us for a focused one-day seminar at the Institut Curie in Paris, dedicated to the latest advancements in spatial analysis and transcriptomics. Immerse yourself in cutting-edge research, methodologies, and tools, focusing on the Visium V2/HD platform. Hear from experts from key institutes and join interactive discussions. Join us for a day of networking, learning, and unlocking new insights in spatial biology! Make sure to reserve your seat:https://pages.10xgenomics.com/WEB-2026-02-EVENT-EMEA-INSTITUT-CURIE-SEMINAR-REGISTRATION-PAGE_LP.html
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Tags: Biology, Spatial biology, Spatial analysis, Insight, Curie Institute
Annonce publiée le 20-12-2025
Institut Curie
Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e -
Cystic fibrosis is a genetic disease characterized by a dehydration of airway mucus leading to increased viscosity, significant inflammation, lung infections and tissue damage. Because progression of the disease cannot be solely explained by genetic factors, some studies are now interested in the intrinsic and extrinsic factors that exacerbate CF symptoms. Among those factors, reduced levels of specialized proresolving lipid mediators (SPM) in CF airway and exposure to air pollution have been reported. In addition, some pollutants have been shown to impact SPM biosynthesis. However, the possible role of air pollution on SPM metabolism dysregulation in CF and the role of SPM in protecting CF airways from air pollution induced damages have not been explored. In our project, we use Scnn1b transgenic mice as a model for CF airway disease. In collaboration with the LISA (Interuniversity Laboratory of Atmospheric Systems / Laboratoire Interuniversitaire des Systèmes Atmosphériques), we study how exposure to a polluted atmosphere can impact the SPM and, more generally, the resolution of inflammation in the airway. Paris postdoc seminar series
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Tags: Lung disorders, Channelopathies, Cystic fibrosis, Fibrosis
Annonce publiée le 18-12-2025
Institut Cochin
Salle Rosalind Franklin -
Invite par: Angelique Michaut
January 26, 2026Duclaux Amphitheater - 9.20am - 6.00 pm An english in person symposium organised since 2015 by the Medical Direction dedicated to translational research. Free but mandatory registration : link to register
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Tags: Stem cells, Tissue engineering, Biotechnology, Organoid
Annonce publiée le 17-12-2025
Institut Pasteur
Batiment Duclaux, salle , -
Invite par: Institut Necker Enfants Malades - Auditorium 3
Seminar topic: Unravelling the molecular mechanisms of clathrin-independent endocytosis to elucidate its pathophysiological functionsAfter obtaining my Ph.D. in bioengineering from UCLouvain (Belgium) in 2010 under the supervision of Prof. Pierre Morsomme, I joined the Institut Curie in Paris in January 2011, where I worked in the laboratory of Dr. Ludger Johannes. In 2015, I returned to UCLouvain for a second postdoctoral period. In January 2020, I was appointed Assistant Professor in cell biology in the Department of Biology, Faculty of Sciences, at the University of Namur (UNamur), Belgium. This position enabled me to launch my own research group and to establish a state-of-the-art bioimaging platform. Leveraging these advanced microscopy tools, my research group focuses on the role of BAR (Bin/Amphiphysin/Rvs) domain proteins in membrane remodelling during cellular processes. In particular, we investigate these mechanisms along two complementary research axes aiming at eludicating: (i) novel clathrin-independent endocytic mechanisms, and (ii) cellular responses to nanoscale environmental cues, especially through nanotopography-driven mechanosensing. Our work builds on the unique ability of BAR domain proteins to sense and/or induce membrane curvature, thereby regulating membrane deformation, vesicle formation, actin remodelling, and signal transduction. Building on our fundamental discoveries, we also aim to expand our research toward more translational directions by connecting these mechanisms to pathophysiological contexts such as cancer and host-pathogen interactions. In 2024, I was promoted to Professor at UNamur. Our research is supported by funding from the FNRS, the Francqui Foundation, and various institutional grants.
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Tags: Membrane biology, Cellular processes, Peripheral membrane proteins, Cell biology, Clathrin, Proteins, Membrane curvature, Endocytosis, BAR domain, Vesicle, Ludger Johannes, Cytosis
Annonce publiée le 15-12-2025
Institut Necker Enfants Malades
Henri-Francois RENARD -
Invite par: Institut Necker Enfants Malades - Auditorium 3
Seminar topic: Immune and metabolic control of sensorimotor physiology and repairI am a Professor of Neuroscience at Imperial College where I hold a Harnett Chair in Restorative Neuroscience and where I lead a research group that investigates physiological and injury mechanisms of the sensorimotor system. I am also a consultant Neurologist within the Imperial NHS Trust. My research and clinical work have broad implications for conditions spanning from traumatic, vascular, inflammatory, degenerative and metabolic damage to the spinal cord, spinal roots and peripheral nerves and for pain syndromes in the nervous system. Previously, since 2006, I worked at the University of Tuebingen, Germany as a Research Group Leader, where I was also a consultant clinician in Stroke and General Neurology.I did my post-doctoral training in Neuroscience studying gene expression regulation after spinal cord injury at Georgetown University, Washington DC, 2001-2004 where I became research Instructor (2004-2006). I studied Medicine at La Sapienza University and did my Neurology training at Catholic University, Rome, Italy.Research in my group aims to investigate the molecular signalling mechanisms that discriminate between axonal regeneration and regenerative failure including following peripheral and spinal cord injuries respectively.Since axonal regeneration, wound healing and repair in the nervous system are imperfect and inefficient, enhancing the regenerative properties and wound healing in the injured central nervous system is critical to promote recovery of function and limit neurological disability in both spinal cord and peripheral nerve disorders.The lab studies how environmental factors including dietary regimens and physical activity affect metabolism and immunity that in turn can influence physiology and repair in the sensorimotor system to optimise sensorimotor function. Our work has broad implications for conditions spanning from traumatic, vascular, inflammatory, degenerative and metabolic damage to the spinal cord, spinal roots and peripheral nerves.
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Tags: Sensory systems, Neurotrauma, Motor system, Skeletal system, Spinal cord, Axon, Lorne Mendell, Somatic nervous system
Annonce publiée le 15-12-2025
Institut Necker Enfants Malades
Simone Di Giovanni -
Invite par: CIRB-College de France
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Annonce publiée le 15-12-2025
College de France
au College de France - Salle D2 - 11 place Marcelin Berthelot - 75005 Paris -
Invite par: CIRB-College de France
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Annonce publiée le 15-12-2025
College de France
au College de France - Salle D2 - 11 place Marcelin Berthelot - 75005 Paris -
Invite par: CIRB-College de France
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Annonce publiée le 15-12-2025
College de France
au College de France - Salle D2 - 11 place Marcelin Berthelot - 75005 Paris -
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Annonce publiée le 12-12-2025
Institut Cochin
Salle Rosalind Franklin -
Chimeric antigen receptor (CAR) T cells have transformed the treatment of hematological malignancies but remain largely ineffective against solid tumors, highlighting the need for innovative strategies to enhance their activity. While recent CAR designs have focused on optimizing biochemical signaling, the biomechanical aspects of T cell activation have been widely overlooked. Yet, T cells are also regulated by the biophysical properties of their targets. Upon engagement, they form an immune synapse (IS) and sense mechanical cues through mechanosensitive receptors, which directly shape their cytotoxic function. These forces depend on target compliance and stiffness, which vary during cancer progression and may act as a “mechanical immune checkpoint” that facilitates tumor immune evasion. We hypothesize that CAR-T cells respond differently to biophysical cues compared with TCR-activated T cells, as suggested by their non-classical IS, morphological changes, and incomplete cytoskeletal remodeling. This reduced mechanosensitivity likely contributes to their limited efficacy in solid tumors. Our project aims to enhance CAR-T performance by (i) mapping how target mechanics influence activation and identifying key mechanosensitive proteins, and (ii) engineering CARs with enhanced force sensing. By integrating biomechanics into the CAR-T engineering toolkit, we aim to open new avenues for overcoming the barriers that currently limit their effectiveness against solid tumors. Paris postdoc seminar series
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Annonce publiée le 12-12-2025
Institut Cochin
Salle Rosalind Franklin -
Intermittent hyperglycemia, characterized by fluctuations in blood glucose levels, has been proposed as a stronger driver of vascular damage than sustained hyperglycemia. This project aims to investigate its role in the development of atherosclerosis. We will use low-density lipoprotein receptor-deficient (Ldlr-/-) mice, a well-established model of atherosclerosis, maintained on a cholesterol-enriched diet to promote lesion formation. To mimic clinical glycemic variability, mice will receive drinking water supplemented with fructose and glucose either continuously or discontinuously, generating sustained versus intermittent hyperglycemia, respectively. We will monitor metabolic parameters, inflammatory markers, and gut microbiota composition to assess systemic and intestinal responses. Atherosclerotic burden will be quantified by histological and morphometric analyses of the aortic root and en face preparations of the aorta. We hypothesize that intermittent hyperglycemia will exacerbate systemic inflammation and accelerate atherosclerotic lesion development compared with continuous exposure, potentially through enhanced oxidative stress and microbiota dysbiosis. This study will provide mechanistic insights into how glycemic fluctuations influence cardiovascular risk, with implications for the management of diabetic patients. Paris postdoc seminar series
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Annonce publiée le 12-12-2025
Institut Cochin
Salle Rosalind Franklin -
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Annonce publiée le 12-12-2025
Centre de Recherche des Cordeliers -
Séminaire en français, à l'invitation de Raphaël Scharfmann. Les helminthes, ces petits vers intestinaux avec lesquels nous avons co-évolué pendant plusieurs millions d’années, sont des maîtres de l’immunité. Ce sont de puissants immuno-modulateurs qui induisent une réponse Th2 contrôlée et réduisent les réponses Th1/Th17. Ils émettent également des centaines de molécules qui agissent à de multiples niveaux pour éviter leur rejet et maintenir leur hôte en bonne santé. Cette présentation vise à mieux comprendre cette thérapie qui pourrait être une piste prometteuse pour de nombreuses maladies à composante inflammatoire. Jacques Le Marois, après une formation scientifique en biologie à l’Ecole Normale Supérieure, a bifurqué ensuite vers l’entreprenariat pendant 27 ans, puis a créé en 2023 une fondation qui vise à financer des projets de recherche et d’études sur des thérapies basées sur du vivant comme la phagothérapie et l’helmintho-thérapie.
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Annonce publiée le 06-12-2025
Institut Cochin
Salle Rosalind Franklin -
Invite par: Arnaud Chastanet
Phages are diverse and abundant within microbial communities, where they play major roles in their evolution and adaptation. Phage replication – and multiplication – is generally thought to be restricted within a single or narrow host range. We use and reprocess published and newly generated proximity ligation-based metagenomic Hi-C (metaHiC) data from various environments to explore virus-host interactions at large scale. We reconstructed 4,975 microbial and 6,572 phage genomes of medium quality or higher. MetaHiC yielded a contact network between genomes and enabled assignment of approximately half of phage genomes to their hosts, revealing that a substantial proportion of these phages interact with multiple species and this, in environments as diverse as oceanic water column or the human gut. This observation challenges the traditional view of a narrow host spectrum of phages by unveiling that multi-host associations are common across ecosystems, with implications how they might impact ecology and evolution and phage therapy approaches.
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Tags: Bacteriophages, Bacteriophage, Phage therapy, Virus, Phage ecology, Corynebacteriophage
Annonce publiée le 05-12-2025
Institut Micalis
Auditorium 442 - Institut Micalis -
Paris post-doc seminar series.
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Tags: Queen of FCW, Serena Deeb, Serena, Doc
Annonce publiée le 05-12-2025
Institut Cochin
Salle Rosalind Franklin -
A year ago, the bioimaging and core facility communities lost a pioneering figure whose influence was especially significant within the Institut Pasteur community. Spencer Shorte’s dedication and contributions were pivotal, particularly within the Cell ...
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Tags: Prophecy, Pasteur Institute, Yasmine Belkaid, Louis Pasteur, Visionary
Annonce publiée le 05-12-2025
Institut Pasteur
Batiment Duclaux, salle Amphitheater Duclaux, -
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Tags: Feminine given names, Patrizia
Annonce publiée le 05-12-2025
Centre de Recherche des Cordeliers -
Invite par: Marie-Agnes Petit
The Microverse is the intricate and interconnected network of microbiomes that covers the Earth and all things on it. A key aim of our research is to understand the drivers of microbiome composition and dynamics, and understand how different biomes select for different microbes. By recycling >22k public metagenomics datasets from 140 different biomes, we charted the first map of the Microverse, providing a unique global overview of the ecological affiliations of different bacteria. Using the Microverse map as a guide, I will present examples of mechanisms that underlie the distribution of microbes and discuss their importance in microbial ecology.
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Tags: Environmental microbiology, Microbiomes, Microbiology, Bioinformatics, Microbiome, Metagenomics
Annonce publiée le 03-12-2025
Institut Micalis
Auditorium 442 - Institut Micalis -
The second meeting of theFBI Mechanobiology WGwill take place on the26 and 27 of March 2026at theInstitut de Biologie Paris Seineand theInstitut Jacques Monodin Paris. The programme will include aseminar by Kate Miroshnikova(NIDDK/NIH, Bethesda USA and Max Planck Institute for Molecular Biomedicine, Munster, Germany),presentations by participantsandpractical mechanobiology workshops(a choice of 4 workshops from a dozen:optical tweezers, micro/nano-fabrication, microfluidics, AFM, micropipette aspiration, mechanical confinement, force measurements, etc?). Preliminary program: Day 1 - 26/03/2026, Paris 5e(IBPS / Curie / IPGG) Morning: scientific presentations, small group discussion Afternoon : 2 sessions of practical workshops on real set-ups in participating labs (Paris 5e) Day 2 - 27/03/2026, Paris 13e(IJM / MSC / LIED) Morning: scientific presentations, poster session Afternoon : 2 sessions of practical workshops on real set-ups in participating labs (Paris 13e) Infos & registration: Registration is free,but places arelimitedandprioritywill be given to contributors whoseabstracts have been selected. Restration link : here
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Tags: Institut Pierre-Gilles de Gennes, Paris Sciences et Lettres University, Bioimaging, IJM, Institut Jacques Monod
Annonce publiée le 28-11-2025
Institut Jacques Monod
Institut Jacques Monod Amphitheatre Buffon, 15 rue Helene Brion, Paris, France -
Invite par: CIRB-College de France
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Tags: Bendor, University College London, Wellcome Trust, Ben-Dor
Annonce publiée le 27-11-2025
College de France
au College de France - Salle D2 - 11 place Marcelin Berthelot - 75005 Paris -
L'Institut Curie et le SiRIC Curie sont heureux d organiser laHuitieme Journee d'echanges sur le Melanome Uveal qui aura lieu levendredi 30 janvier 2026, en presentiel (a l'Institut Curie, Paris) et en ligne. Cette journee, destinee aux patient(e)s et a leurs proches, permettra d'en apprendre plus sur la maladie et sa prise en charge, ainsi que sur la recherche qui est menee par nos medecins et chercheurs. Le programme est en cours de finalisation et sera diffuse bientot aux inscrits et sur le site https://siric.curie.fr/page/journees-melanome-uveal. Cette annee encore, plusieurs presentations seront consacrees au vecu, aux effets secondaires, aux essais cliniques et a l accompagnement socio-professionnel. Vous pouvezvous inscrire sur ce site: https://my.weezevent.com/journee-melanome-uveal-2026-8eme-edition L'inscription est gratuite mais obligatoire, afin de nous aider a preparer au mieux cette journee. Pour toute question ou probleme rencontre, merci de nous ecrire a m.melanome-uveal2026@curie.fr.
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Annonce publiée le 25-11-2025
Institut Curie
Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e -
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Tags: Marie-Hlne, Helene, Marie-Hlne Verlhac
Annonce publiée le 21-11-2025
Centre de Recherche des Cordeliers -
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Tags: Krysko
Annonce publiée le 21-11-2025
Centre de Recherche des Cordeliers -
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Tags: Weil, Weil der Stadt, Richard Weil
Annonce publiée le 20-11-2025
Centre de Recherche des Cordeliers -
Plus d'infos...
Tags: Geraldine Jones, Geraldine, Geraldine Gonzlez, Desmond
Annonce publiée le 20-11-2025
Centre de Recherche des Cordeliers -
Plus d'infos...
Tags: Gregory
Annonce publiée le 20-11-2025
Centre de Recherche des Cordeliers -
We& investigate the dynamic interactions between leukemic cells and their vascular microenvironment. Combining& in vivo& imaging, humanized 3D models, and multi-omics approaches, we explore how the niche contributes to leukemia progression, treatment resistance, and immune evasion, particularly in the bone marrow and central nervous system.
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Tags: Stem cells, Tumor microenvironment, Tumors, Bone marrow, Multiomics
Annonce publiée le 17-11-2025
Centre de Recherche des Cordeliers -
Cet evenement d'une journee sera consacre a la recherche fondamentale et appliquee dans le domaine en pleine expansion des interactions entre cellules stromales (notamment fibroblastes et cellules endotheliales) et cellules immunitaires au sein du microenvironnement tumoral (TME). Au cours de la derniere decennie, le stroma tumoral est apparu comme une cible therapeutique prometteuse dans le cancer, les fibroblastes associes au cancer (CAF) jouant un role cle dans la structuration du TME, la regulation de la croissance tumorale, la promotion de l'evasion immunitaire et la contribution a la resistance auxchimiotherapie et auximmunotherapies. Les scientifiques que nous avons invites et qui ont confirme leur participation pour presenter leurs projets et leurs resultats les plus recents dans le domaine du stroma, de l'immunite et du cancer sont listes ci-dessous par ordre alphabetique : CONFERENCIERS INVITES (KEYNOTE) Alexandra Naba - USA Shannon Turley - USA INTERVENANTS Corinne Bousquet - France Cedric Gaggioli - France Fatima Mechta-Grigoriou - France Lucie Peduto - France Helene Salmon - France Karine Tarte - France Danijela Vignjevic - France En plus de ces intervenants, trois jeunes post-doctorants/chercheurs (1 de l'UE, 1 hors Paris et 1 de Paris) seront selectionnes pour des presentations courtes (10 minutes + 5 minutes de questions). La selection se fera sur la base des resumes de posters soumis lors de l'inscription. Nous veillerons a assurer un equilibre hommes-femmes parmi les intervenants. L'inscription au symposium sera gratuite mais obligatoire. Nous diffuserons largement l'annonce du symposium afin de maximiser sa visibilite et d'attirer des chercheurs, etudiants, medecins et ingenieurs internationaux, qui prendront en charge leurs frais de deplacement et d'hebergement. Une session poster accompagnee de vin et fromage se tiendra a la fin du symposium, mais les posters seront affiches des le matin pres de la zone cafe/dejeuner pour encourager les echanges tout au long des pauses. L'IHU Cancers des Femmes de l'Institut Curie sponsorise l'evenement, car le theme s'inscrit dans l'une de ses priorites de recherche. Inscription gratuite mais obligatoire avant le 10 juin 2026:https://forms.office.com/e/pMdqmCLZcP
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Annonce publiée le 14-11-2025
Institut Curie
Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e -
Vers une comprehension quantitative de la dynamique nucleaire au cours du developpement et des maladies Les objectifs de ce cours sont de fournir un apercu des mecanismes epigenetiques et de leurs liens avec la chromatine. Les differentes fonctions du noyau impliquant le genome et son organisation seront discutees en insistant sur les limites technologiques et les nouvelles approches experimentales developpees. Les liens entre la perte des fonctions du noyau et le developpement de pathologies humaines seront presentes. Cette annee ce cours abordera plus amplement les aspects physiologiques et pathologiques de l'epigenetique, en lien avec le metabolisme et la determination et maintien de l'identite cellulaire. Le succes de ce cours repose sur une forte contribution des participants qui doivent assister de facon tres proactive a l'ensemble des activites organises, tels que les sessions de presentations de posters, les analyses d'articles (Journal Club), et les ateliers. (voir section Travail personnel et le Programme pour plus d information). Une session speciale sera aussi dediee a aux presentations et echanges avec 1-2 alumni du cours qui ont poursuivi leur carriere dans le domaine de l'epigenetique.
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Annonce publiée le 11-11-2025
Institut Curie
Centre de recherche - Paris - Amphitheatre Helene Martel-Massignac (BDD) -
Cette journee sera consacree aux recherches fondamentales et appliquees dans le domaine en pleine expansion des interactions entre cellules stromales (en particulier les fibroblastes et les cellules endotheliales) et cellules immunitaires au sein du microenvironnement tumoral (TME). Au cours de la derniere decennie, le stroma tumoral est devenu une cible therapeutique prometteuse dans le cancer, les fibroblastes associes au cancer (CAF) jouant un role cle dans la structuration du TME, la regulation de la croissance tumorale, l'evasion immunitaire et la resistance aux chimiotherapies et immunotherapies. Le nombre d'experts en France travaillant dans ce domaine ne cesse de croitre, et nous ressentons le besoin d'organiser un symposium qui reunisse des chercheurs experimentes et des debutants afin de favoriser la creation d'une communaute. Inspire par les initiatives fructueuses des dernieres decennies autour de la recherche sur les lymphocytes et les cellules myeloides, ce symposium vise a aider un cercle pluridisciplinaire d'experts interesses par les fibroblastes du TME a etablir des consensus sur les pratiques experimentales, proposer des nomenclatures unifiees, partager des resultats et echanger des modeles. L'objectif de ce symposium est de renforcer les collaborations naissantes et d'accroitre la visibilite internationale de l'Institut Curie et de la France dans le domaine de l'etude du stroma dans le cancer. Il s'adresse a des personnes disposant d'au moins des connaissances de base en biologie ou immunologie (niveau recommande : Master). Cet evenement sera egalement une opportunite pour faire progresser la recherche translationnelle et le developpement de traitements anticancereux ciblant specifiquement les composants stromaux. Le symposium se tiendra le mardi 23 juin 2026, de 8h30 a 20h, dans l'Amphitheatre Constant Burg (12 rue Lhomond, 75005 Paris, niveau -1), le plus spacieux et confortable de l'Institut Curie, avec ses 196 places. Nous esperons accueillir entre 120 et 150 participants. Les scientifiques que nous avons invites et qui ont confirme leur participation pour presenter leurs projets et leurs resultats les plus recents dans le domaine du stroma, de l'immunite et du cancer, sont listes ci-dessous par ordre alphabetique : CONFERENCIERS PRINCIPAUX (KEYNOTE SPEAKERS) Alexandra Naba - Etats-Unis Shannon Turley - Etats-Unis INTERVENANTS (SPEAKERS) Corinne Bousquet - France Cedric Gaggioli - France Fatima Mechta-Grigoriou - France Lucie Peduto - France Helene Salmon - France Karine Tarte - France Danijela Vignjevic - France En complement, trois jeunes postdocs/chercheurs (1 venant de l'UE, 1 hors Paris et 1 parisien) seront selectionnes pour des presentations courtes (10 minutes + 5 minutes de questions). La selection se fera sur la base des resumes des posters soumis lors de l'inscription. Nous veillerons autant que possible a respecter la parite hommes-femmes parmi les intervenants. L'inscription au symposium sera gratuite mais obligatoire. Nous diffuserons largement l'annonce afin de maximiser la visibilite et d'attirer des chercheurs, etudiants, medecins et ingenieurs internationaux, qui devront prendre en charge leurs frais de voyage et d'hebergement. Une session de posters accompagnee d'un « vin et fromage » sera organisee en fin de symposium, mais les posters pourront etre affiches des le matin a proximite de l'espace cafe/dejeuner pour favoriser les echanges tout au long des pauses. L'IHU Cancers de femmes de l'Institut Curie sponsorise cet evenement, dont la thematique correspond a l'un de ses axes de recherche.
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Annonce publiée le 08-11-2025
Institut Curie
Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e -
Invite par: Anna-Bella Failloux
Grand challenges in vector-borne diseases Controlling vectors in the context of climate and environmental changes June 5th 2026 ? Institut Pasteur, Paris, France Registration is free but mandatory Registration form As part of the ...
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Tags: Infectious diseases, Epidemiology, Vector calculus, Disease transmission, Disease vector, Parasitology, Vector, Euclidean vector, Climate change and infectious diseases
Annonce publiée le 07-11-2025
Institut Pasteur
Batiment: Duclaux Salle: Amphitheatre Duclaux -
TBA
Plus d'infos...
Tags: Randlett, Draft:Poongodi, Draft:Punitha
Annonce publiée le 06-11-2025
Laboratoire Jean Perrin
Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 -
Ce cours a pour but de rassembler les bases, les connaissances recentes et les perspectives therapeutiques autour de l'utilisation du systeme immunitaire de l'enfant pour cibler les cancers pediatriques, des particularites biologiques chez l'enfant aux innovations les plus poussees d'ingenierie cellulaire. Il se focalisera plus particulierement sur les tumeurs solides pediatriques, en tirant les enseignements des succes recents et defis restants dans les hemopathies malignes de l'enfant. Il rassemblera des acteurs nationaux et internationaux impliques dans ce domaine, dont les avancees precliniques et cliniques recentes permettent d'esperer des progres therapeutiques majeurs dans les annees a venir. Objectifs Exposer aux participants les recentes avancees en immunotherapie des cancers pediatriques. Mettre en valeur les specificites des cancers pediatriques et de l'immunite des enfants a prendre en compte pour les approches d'immunotherapie. Explorer leur developpement en recherche fondamentale, preclinique et clinique.
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Annonce publiée le 23-10-2025
Institut Curie
Centre de recherche - Paris - Amphitheatre Helene Martel-Massignac (BDD) -
Ce cours etudiera le spectre complet de la biologie du genome, de l'organisation et de l'imagerie de la chromatine a l'epigenetique, a l'ADN mobile et a la dynamique evolutive. Au cours de six sessions ciblees, des experts de renommee internationale presenteront leurs dernieres decouvertes liees a l'identification et a la caracterisation fonctionnelle du genome non codant et discuteront de nouveaux concepts de regulation et d'evolution du genome, en mettant l'accent sur les outils experimentaux et informatiques. Les sessions thematiques comprendront des approches unicellulaires et translationnelles de pointe pour demeler la plasticite et l'heterogeneite cellulaires, interroger la regulation des genes et suivre l'evolution du genome dans la physiologie et la maladie. Ce cours offrira aux jeunes etudiants et aux chercheurs l'occasion d'elargir leurs connaissances et de discuter de leurs travaux avec une communaute scientifique internationale dans un environnement chaleureux et stimulant a l'Institut Curie a Paris.
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Annonce publiée le 23-10-2025
Institut Curie
Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e -
Invite par: ESCHBACH Claire
Plus d'infos...
Tags: Nervous system, Neurology, Neurophysiology, Neuroscience, Brain
Annonce publiée le 22-10-2025
NeuroPSI
Salle de conference Albe-Fessard -
TBA
Plus d'infos...
Tags: Recho Omondi, Draft:God Save The Tuches, Draft:Poongodi
Annonce publiée le 18-10-2025
Laboratoire Jean Perrin
Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 -
TBA
Plus d'infos...
Tags: Draft:God Save The Tuches, Draft:Poongodi
Annonce publiée le 18-10-2025
Laboratoire Jean Perrin
Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 -
Invite par: Cirb
Plus d'infos...
Annonce publiée le 15-10-2025
College de France
au College de France - Salle D2 11 place Marcelin Berthelot - 75005 Paris -
Invite par: Cirb
Plus d'infos...
Annonce publiée le 15-10-2025
College de France
au College de France - Salle D2 11 place Marcelin Berthelot - 75005 Paris -
Invite par: CIRB-College de France
Plus d'infos...
Annonce publiée le 15-10-2025
College de France
au College de France - Salle D2 11 place Marcelin Berthelot - 75005 Paris -
Extracellular vesicles (EVs) are increasingly recognized as critical mediators in the pathogenesis of fungal infections, particularly those caused by Cryptococcus species—opportunistic pathogens responsible for life-threatening diseases in immunocompromised individuals. While structural models of fungal EVs have been proposed, they often overlook the natural heterogeneity within EV populations. Although the identification and functional analysis of EV subpopulations have been well explored in mammalian systems—and to a lesser extent in plants—this area remains underexplored in fungi. In this study, we isolated and characterized EVs from Cryptococcus using a combination of size-, weight-, and density-based separation techniques, allowing us to resolve distinct EV subpopulations. Importantly, we identified a previously uncharacterized small EV population, currently undergoing functional investigation. Preliminary data suggest this subpopulation may carry unique molecular signatures, with several candidates showing promise as biomarkers. Given the established roles of Cryptococcus-derived EVs in host–pathogen interactions, immune modulation, and the dissemination of virulence factors, these findings could significantly enhance our understanding of fungal pathogenesis. Ultimately, by revealing new layers of EV diversity, our work aims to facilitate the development of targeted biomarkers for early detection and to support novel therapeutic strategies focused on EV-mediated processes. Paris postdoc seminar series
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Tags: Tremellomycetes, Yeasts, Vesicles, Cell biology, Zoonoses, Extracellular vesicle, Cryptococcus, Vesicle, Pathogenic fungus, EV, Arturo Casadevall, Thomas G. Mitchell
Annonce publiée le 01-10-2025
Institut Cochin
Salle Rosalind Franklin -
Invite par: Francois Bontems
ReCombinaisons se veut un espace de rencontre et de discussion entre chercheuses et chercheurs (biologie-sante, sciences humaines et sociales, philosophie), autrices, auteurs et artistes de science-fiction, et public le plus large possible, pour reflechir ...
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Annonce publiée le 26-09-2025
Institut Pasteur
Batiment: CIS Salle: Auditorium -
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Tags: Bregaglia, ItalySwitzerland border, Pizz Gallagiun
Annonce publiée le 23-09-2025
Inst. Bio. Paris Seine
7-9 quai Saint Bernard, 75005 Paris -
Nous avons le plaisir d’annoncer la prochaine conference internationale : « Forces at Play : Emerging Themes in Mechanobiology - In Memoriam of Professor Michael P. Sheetz » qui se tiendra du 19 au 21 janvier 2026 a l’Institut Jacques Monod, Universite Paris Cite, Paris, France. Cet evenement special rend hommage a l’heritage du professeur Michael P. Sheetz, pionnier dans le domaine de la mecanobiologie, et reunira des chercheurs, des etudiants et des innovateurs de premier plan du monde entier afin d’explorer les dernieres avancees en matiere de mecanique cellulaire, de biophysique et de disciplines connexes. Retrouvez la liste des speakers ainsi que les informations concernant les inscriptions sur le site : https://mikeinmemoriam.sciencesconf.org/?lang=en Les inscriptions sont ouvertes jusqu’a la mi-novembre. Le comite d’organisation : Nicolas Biais, Nils Gauthier, Benoit Ladoux, Olivier Rossier
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Annonce publiée le 20-09-2025
Institut Jacques Monod
Institut Jacques Monod Amphitheatre Buffon, 15 rue Helene Brion, Paris, France -
Plus d'infos...
Annonce publiée le 02-09-2025
Inst. Bio. Paris Seine
7-9 quai Saint Bernard, 75005 Paris -
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Tags: Ens, cole normale suprieure
Annonce publiée le 30-08-2025
Neural Networking Night
pub Le Piano Vache - 8 Rue Laplace, 75005 Paris -
Plus d'infos...
Tags: Fricker, Desdemona
Annonce publiée le 19-08-2025
Neural Networking Night
pub Le Piano Vache - 8 Rue Laplace, 75005 Paris -
Plus d'infos...
Tags: Saclay, Paris-Saclay University
Annonce publiée le 19-08-2025
Neural Networking Night
pub Le Piano Vache - 8 Rue Laplace, 75005 Paris -
Plus d'infos...
Tags: Ranft, Ens
Annonce publiée le 19-08-2025
Neural Networking Night
pub Le Piano Vache - 8 Rue Laplace, 75005 Paris -
Plus d'infos...
Tags: Operas, Ulisse, Flavio Manzoni, Ulisse Cantagalli
Annonce publiée le 19-08-2025
Neural Networking Night
pub Le Piano Vache - 8 Rue Laplace, 75005 Paris -
Plus d'infos...
Tags: Ens, Carlos Costa
Annonce publiée le 19-08-2025
Neural Networking Night
pub Le Piano Vache - 8 Rue Laplace, 75005 Paris