Thursday 25 June 2026 12:00

From Tissues to Trials: Designing and Analyzing Biomarker-Driven Clinical Trials
Susan Halabi | Duke Cancer Institute, Durham, USA


Tags: Biomarkers, Cancer biomarker, Clinical trial, Imaging biomarker Published on 21-06-2026

	Institut Gustave Roussy salle Pierre Denoix, etage 15 - ascenseur C du batiment principal, 114 rue Edouard-Vaillant, 94 800 Villejuif Contact : kristine.schauer at gustaveroussy.fr

Monday 29 June 2026 11:00

Nuclear nutrient sensing signaling of Class 3 PI3K in metabolic homeostasis
Ganna Panasyuk | INEM, equipe Mecanismes de detection des nutriments


Invited by: Jeremie Gautheron Dr Ganna Panasyuk is a principal investigator at the Institute Necker Enfants Malades (INEM, INSERM U1151, Paris), where she leads the Lab of Nutrient Sensing Mechanisms. Her research explores how nutrient and metabolic signaling pathways control cell adaptation, identity, and disease, with a strong focus on liver metabolism and liver pathophysiology. Dr. Panasyuk trained in molecular biology in Kyiv, Ukraine, and later specialized in growth-control signaling, including mTOR/PI3K pathways, during postdoctoral work at University College London and INSERM Paris. Since 2019, she has served as INSERM Research Director at INEM. Her laboratory investigates class 3 PI3K, an evolutionarily conserved lipid kinase and nutrient sensor, using cell systems, patient-derived organoids, multi-omics approaches, subcellular metabolomics, and transgenic in vivo models. Her work is supported by national and European funding, including an ERC Consolidator Grant. In this seminar, Dr. Panasyuk will discuss how class 3 PI3K coordinates liver adaptation to fasting and metabolic stress. While acute nutrient deprivation activates cytosolic catabolic pathways such as autophagy, prolonged fasting requires transcriptional and epigenetic rewiring. Recent work from her team shows that class 3 PI3K not only regulates autophagy and lysosomal activity, but also interacts with RNA polymerase II, associates with active transcription sites, and supports liver metabolic rhythmicity. These findings position nuclear class 3 PI3K signaling as a key regulator of hepatic metabolic homeostasis, with implications for liver disease, metabolic syndrome, and cancer. More details... Tags: Signal transduction, Immunology, Cell biology, Organelles, Vesicles, MTOR, Autophagy, Nutrient sensing, Lysosome, Phosphoinositide 3-kinase, Metabolism Published on 21-06-2026

	CRSA salle des conferences au RDC du batiment Kourilsky, 184 rue du Faubourg Saint-Antoine - 75012

Monday 29 June 2026 12:15

Toxicologie medico-legale : applications historiques
Philippe Charlier and Laurene Dufayet | LAAB/UVSQ - Musee Quai Branly and UMR-S 1144 Optimisation Therapeutique en Neuropharmacologie


Invited by: Seminaires Anim'Pharma Published on 21-06-2026

	Faculte de Pharmacie de Paris salle des Actes de la Faculte de Pharmacie de Paris, 4 avenue de l'Observatoire 75006. Inscription OBLIGATOIRE aupres de luciechevillard at gmail.com

Thursday 02 July 2026 0:00

Driver mutations and immune microenvironment in acute myeloid leukemia
Antonio CURTI


Notice biographique Le Dr Antonio Curti (MD, PhD) est médecin-chercheur et praticien à l'Institut d'hématologie « L. & A. Seràgnoli » de l'Université de Bologne. Il dirige des programmes de recherche portant sur l'immunobiologie des leucémies et sur des études cliniques consacrées aux leucémies aiguës, en se concentrant tout particulièrement sur les interactions entre les cellules tumorales et le microenvironnement immunitaire. Ses travaux couvrent les domaines de l'immunologie fondamentale et translationnelle, incluant l'étude des mécanismes d'échappement immunitaire dans les leucémies et le développement de stratégies d'immunothérapie innovantes, telles que les thérapies fondées sur les cellules NK alloréactives. Auteur de plus de 160 publications, le Dr Curti est un membre actif de réseaux de recherche en hématologie, tant à l'échelle nationale qu'internationale. Invité par Diana Passaro More details... Published on 19-06-2026

	Institut Cochin Salle Rosalind Franklin

Thursday 20 August 2026 11:30

IMAGING ACROSS SCALES ? CATCHING CONCURRENT ORGANELLE DYNAMICS IN LIVING CELLS AND TISSUES


In animal development, timing matters. Phenomena operating within distinct levels-those of molecules, organelles, cells, or tissues, span the extremes of timescales and give rise to the clock work of development. Developmental programs are under genetic controf?however, the physical basis of these processes lie within the components that drive it - molecules, organelles, cells, supracellular assemblies. Capturing these mechanisms requires imaging approaches that can span different scales, molecular to tissue level processes demand both high spatial and temporal resolutions simultaneously. In the first part, I will introduce light-sheet microscopy and exemplify cell biological studies using endosomal timekeeping of biochemical reactions at single cell levels. However, these approaches are limited by the absence of physiological context as cells are investigated in isolation. In the second part, I will describe imaging approaches based on Airy beam-based light sheet microscopy of organelles in tens to hundreds of cells in a few hundred micrometre-wide tissue environments that will enable. This approach achieves a typical resolution of 320 nm over 266 × 266 × 100 ?m3 volumes at a temporal rate of 0.05 Hz that now allows tracking molecules and organelles in large living tissues. I will detail out how such imaging across scales allows discovering new phenomena in tissue morphogenesis using Drosophila as a model system, where we address how during germ band extension, the monolayer of cells from the central side wrap around the high curvature posterior pole onto the dorsal surface. We discover an interplay between curvature, waves of cell divisions within domains and tissue fluidization that work together to preserve segment boundaries. Finally, I will conclude by addressing data challenges, including visualization and analysis, and outlook on the future of biological problems that these approaches unravel. More details... Tags: Cell, In science, Organelle, Tissue, Organelles, Laboratory techniques, Draft:Spatial Proteomics, Live-cell imaging Published on 18-06-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie

Thursday 24 September 2026 12:00

Cryo-EM and cryo-ET of membrane remodeling in autophagy and endolysosomes


James H. Hurleyis a leading structural biologist ( https://vcresearch.berkeley.edu/faculty/james-hurley), whose work has transformed our understanding of the interplay between proteins and membrane lipids. He is especially known for seminal studies to uncover molecular mechanism ofthe ESCRTmachinery, HIVtrafficking, retrograde trafficking by retromer, and the autophagycore complexes, combining crystallography, cryo-EM, and reconstitution on model membranes to explain how cells sort cargo, remodel membranes, and initiate autophagy ( https://scholar.google.com/citations?user=SoNEZA8AAAAJ&hl=en). More details... Tags: Cell biology, Protein structure, Organelles, Autophagy, Cell death, Immunology, Cryogenic electron microscopy, Structural biology, Lysosome Published on 18-06-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie

Monday 28 September 2026 8:00

International symposium of the Leukemia Institute
Chloe Baron, Lina Benajiba, Nicolas Boissel, Marcus Buschbeck, Hugues de The, John Dick, Alexandre Fagnan, Brunangelo Falini, Margaret Goodell, Olivier Hermine, David Michonneau, Diana Passaro, Emmanuelle Passegue, Francoise Porteu, Kevin Rouault-Pierre, Michel Sadelain, Marie Sebert, Jean Soulier, Ulrich Steidl, Alexander Waclawiczek, Eunice Wang, Marcin Wlodarski | plusieurs sites


Invited by: the Leukemia Institute More details... Tags: Leukemia Published on 18-06-2026

	College de France amphitheatre Marguerite de Navarre du College de France

Tuesday 30 June 2026 15:00

CANCELLED : Innovation en imagerie cellulaire et tissulaire
Florence Niedergang, Yannick Allanore, Gilles Renault, Mirko Minini, Edouard Lecarpentier, Pierre Bourdoncle, Alain Schmitt


Invited by: Rencontre Clinico Biologique More details... Tags: Imaging Published on 18-06-2026

	Institut Cochin salle Rosalind Franklin, 22 rue Mechain - 75014

Tuesday 30 June 2026 11:00

Enzymatic Syntheses of Base-Modified and Hypermodified Nucleic Acids for Chemical Biology, Bioanalysis and Aptamer Selection


Invited by: Nazarii Sabat Prof. Michal Hocek, PhD DSc. Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences ABSTRACT The lecture will summarize recent results of the Hocek group in syntheses of base-modified nucleotides, as ... More details... Tags: Nucleic acids, DNA, Biotechnology, Peptides, RNA, Michal Hocek, Aptamer, Nucleotide, Bioanalysis Published on 17-06-2026

	Institut Pasteur Batiment F. Jacob , salle F. Jacob Auidtorium ,

Friday 03 July 2026 12:00

Vagal Signaling in Psychiatric Disorders: Toward a Reverse-Translational Neuroscience of BrainBody Interactions
Prof. Julian Koenig | University of Cologne, Germany


Invited by: Dr F Koukouli The vagus nerve has emerged as central hub of brainbody communication and a promising target for psychiatric research. Across a range of mental disorders, including depression, anxiety, and stress-related conditions, alterations in autonomic regulation and vagal functioning have been linked to symptom expression, disease trajectories, and treatment outcomes. At the same time, vagus nerve stimulation has attracted growing interest as a therapeutic approach capable of modulating neural circuits implicated in affective and cognitive processes. In this talk, I will trace the emergence of the vagus nerve as a focus of psychiatric research, from early theoretical accounts of autonomic regulation and emotion to contemporary investigations of vagal biomarkers and neuromodulation-based interventions. Drawing on evidence accumulated over the past decades, I will examine how findings from human studies have shaped our understanding of vagal functioning across development and psychopathology, and how these observations have informed the development of invasive and non-invasive treatment approaches. Particular attention will be given to the promises, limitations, and evolving mechanistic frameworks that have accompanied this progression. I will argue that future progress requires a stronger reverse-translational framework that moves beyond largely correlational biomarker research in humans. Clinical observations in patients should increasingly guide mechanistic investigations in experimental models, while insights from basic neuroscience can inform hypothesis-driven studies in humans. At the same time, advancing the field will require novel methodological approaches that move beyond the current reliance on proximal and indirect indices of vagal function. Such an iterative exchange between clinical psychiatry and basic neuroscience, may provide a more mechanistic understanding of vagal signaling in mental health and support the development of targeted and personalized interventions. More details... Published on 16-06-2026

	Institut de Psychiatrie et Neurosciences de Paris Room D Levy, Institut de Psychiatrie et Neurosciences de Paris (IPNP) UMR 1266 INSERM - Universite Paris Cite, 102-108 Rue de la Sante - 75014 Paris

Thursday 09 July 2026 0:00

eIF2alpha kinase HRI in innate immunity, proteostasis and mitochondrial stress
Damien ARNOULT


La kinase HRI (eIF2?) dans l'immunité innée, la protéostasie et le stress mitochondrial Damien Arnoult est Directeur de Recherche (DR2) au CNRS. Ses travaux portent sur les mécanismes cellulaires et moléculaires qui contrôlent les réponses au stress, l’immunité innée et la mort cellulaire. Au cours des deux dernières décennies, il a étudié le rôle central des mitochondries comme plateformes de signalisation impliquées dans les réponses antivirales et inflammatoires. Ses recherches ont notamment permis d’éclairer les liens entre dynamique mitochondriale, homéostasie cellulaire, activation des voies de l’immunité innée et pathologies associées à l’inflammation chronique. Ses travaux se situent à l’interface de la biologie cellulaire, de l’immunologie et du métabolisme cellulaire. Il développe actuellement des approches visant à mieux comprendre comment les mitochondries coordonnent les réponses adaptatives des cellules face aux stress environnementaux et aux agressions infectieuses. invité par Véronique WITKO-SARSAT More details... Published on 16-06-2026

	Institut Cochin Salle Rosalind Franklin

Friday 03 July 2026 11:00

DSCB Seminar - Dr. Agnete Kirkeby, University of Copenhagen, Denmark - Modelling and repairing the human brain with pluripotent stem cells


Invited by: Laure Bally-Cuif Dr Kirkeby has many years of expertise in generating accurately regionalised human neural cells from pluripotent stem cells (hPSCs) and has been responsible for the preclinical development of the first European hPSC-derived dopamine cell ... More details... Tags: Stem cells, Biotechnology, Cell biology, Cloning, Developmental biology Published on 15-06-2026

	Institut Pasteur Batiment Monod, salle Amphi Ullmann,

Friday 26 June 2026 11:00

DSCB Seminar - Dr. Steffen Rulands, Ludwig Maximilian University of Munich, Germany - Emergent dynamics in cells and tissues: a statistical physics approach


Invited by: Laure Bally-Cuif Steffen Rulands is a professor in theoretical physics at the LMU Munich. He obtained his PhD in theoretical physics at the LMU in 2013, went on to do a postdoc at the university of ... More details... Tags: LMU Munich, Munich Published on 15-06-2026

	Institut Pasteur Batiment Monod, salle Amphi Ullmann,

Thursday 16 July 2026 14:00

Largescale multiomic modelling of human brain reveals metabolic adaptation that precedes bioenergetic collapse in Alzheimer?s disease
Scott AYTON


Proteopathy and synaptic dysfunction accumulates over decades in Alzheimer's disease (AD), accompanied by marked mitochondrial changes and oxidative stress. Adaptive metabolic programs may oppose degeneration, such as the pentose phosphate pathway (PPP), a major source of NADPH required for antioxidant defence. But the PPP, and upper-glycolytic pathways in general are poorly characterised in extant AD metabolomic workflows, because phosphorylated metabolites (characteristic of upper glycolysis metabolites) have low volatility, hydrophilicity, and ionization efficiency. Phosphate groups also interfere with the protonation or deprotonation of metabolites during the ionisation process in MS, leading to poor sensitivity and resolution, resulting in deficient metabolic profiling of the AD brain. To address this, we performed the largest integrated (phospho)metabolomic and proteomic analyses in human brain tissue spanning the AD clinicopathological spectrum (n = 625) accompanied with proteomics to reconstruct the molecular natural history of AD. We identified the PPP as the metabolomic pathway most strongly associated with AD, alongside enrichment of the Warburg effect and fructose and mannose catabolism. Discriminative Events-Based Modelling revealed that metabolites capable of being diverted into the PPP transitioned to abnormal states at an early event stage in AD, proximal to amyloid accumulation and synaptic dysregulation. Decreased mitochondrial oxidative phosphorylation represented the final event stage, most proximal to iron accumulation glutathione depletion and evidence of oxidative stress. Therefore, the molecular natural history of AD is characterized by early preservation of the PPP that supports redox homeostasis but may occur at the cost of progressive N-glycosylation loss in aggregation-prone synaptic proteins. Prolonged central carbon flux diversion into the PPP later manifests in mitochondrial protein loss and oxidative stress in the degenerative phase of the disease. More details... Tags: Biochemistry, Bioenergetics, Biophysics, Cell biology, Energy, Mitochondrion, Pentose phosphate pathway, MTOR Published on 12-06-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e

Friday 03 July 2026 11:45

How do cells build complicated organelles?
Jordan Raff


Invite par l'Institut Jacques Monod, Prof Jordan Raff, (Sir William Dunn School of Pathology, University of Oxford) presentera une conference de l'Institut Jacques Monod : How do cells build complicated organelles? Resume: A key feature of all living things is their ability to assemble complicated structures using dilute building blocks present in the cell. How cells achieve this remarkable feat of bioengineering is largely unknown. Centrosomes are major microtubule (MT) organising centres and important signalling hubs in many cells. They are an excellent model for studying organelle biogenesis as they comprise 10s-100s of copies of several hundred different types of protein yet, like the DNA, they precisely duplicate once per cell cycle. We have recently reconstituted centrosome duplication on synthetic beads programmed to recruit core centrosome assembly proteins when injected intoDrosophilaembryos. These beads generate structures that appear to be functionally indistinguishable from centrosomes: they recruit centriole/centrosome proteins, organise MTs and proceed through multiple rounds of high-fidelity duplication, all in synchrony with the endogenous centrosomes. The beads function as seeds that recruit biogenesis-promoting proteins to stimulate the assembly of relatively simple scaffolds that direct centrosome self-assembly. This Seed-Scaffold-Self-Assemble? mechanism may represent a general principle of organelle biogenesis, explaining how simple molecular inputs can generate complex structures without the need to copy a pre-existing template. More details... Tags: Centrosome, Cell biology, Organelles, Organelle biogenesis, Microtubule, Centriole, Cell, Organelle, Centrosome cycle, Aster Published on 11-06-2026

	Institut Jacques Monod Institut Jacques Monod Amphitheatre Buffon, 15 rue Helene Brion, Paris, France

Tuesday 22 September 2026 9:00

Postdoc Appreciation Week Symposium


The Postdoc Appreciation Week will be back for its second edition this September: the opportunity to celebrate the unique contribution of the postdoctoral community to science. Postdoc Appreciation Week (PAW) is a global tradition ... More details... Tags: Academic administration, Postdoctoral researcher, National Postdoctoral Association Published on 11-06-2026

	Institut Pasteur Batiment: Center Francois Jacob Salle: CFJ auditorium & Atrium

Tuesday 01 December 2026 11:30

TBA
Dr Bo Gao | School of Biomedical Sciences


Invited by: CIRB-College de France More details... Published on 10-06-2026

	College de France au College de France Salle D2 11 place Marcelin Berthelot - 75005 Paris

Tuesday 29 September 2026 11:30

TBA
Dr Raffaella Tonini | Institut Italien de Tecnologie


Invited by: CIRB-College de France More details... Published on 10-06-2026

	College de France au College de France Salle D2 11 place Marcelin Berthelot - 75005 Paris

Friday 09 October 2026 0:00

3rd symposium: on The Connection between Physics and Metabolism In brain Functions
Barcelona Children's Hospital Sant Joan de Deu | nd the Paris Brain Institute, Drs A. Garcia-Cazorla and Fanny Mochel invite you to Barcelona a city that has, over recent decades, consolidated its position as one of Europe's most dynamic and vibrant hubs for science and health.


Previous editions have explored topics ranging from mechanotransduction the mechanical forces that shape brain development to the physics of neurotransmission, spatial mechanotranscriptomics, and the emerging field of mechanomedicine. Building on these advances, this year&'s symposium will delve deeper into the physical principles that govern brain metabolism and function, continuing to expand the frontiers of neuroscience. More details... Tags: Neurology, Nervous system, Neurophysiology, Neuroscience Published on 09-06-2026

	I. Cerveau et de la Moelle Exciting developments in quantum biology highlighted by an inaugural conference featuring Sonia Contera, Professor of Biological Physics at the University of Oxford.Physical approach to brain metabolism, incorporating thermodynamic principles and the emerging concept of photons as synaptic transmitters.A pioneering discipline at the intersection of biophysics, metabolism and medicine, focusing on mechanodiseases.A thought-provoking closing lecture on the relationship between metabolism and cognition.

Monday 30 November 2026 9:00

International conferences Integrative Microbiome Program at Pasteur


Invited by: Benoit Chassaing To officially launch this major programme, the Pasteur Institute invites you to a two-day series of talks featuring speakers from around the world as well as from the Pasteur Institute. Further details on the ... More details... Tags: Microbiome, Pasteur Institute, Louis Pasteur, Bioinformatics, Human Microbiome Project Published on 09-06-2026

	Institut Pasteur Batiment: CIS Salle: CIS

Monday 19 October 2026 0:00

17e edition - Biologie du Developpement


From Stem Cells to Morphogenesis Ce cours intensif combine une formation theorique et pratique afin d'explorer les concepts fondamentaux, les defis et les technologies de la biologie du developpement moderne. Le programme couvre des sujets allant de la regulation de l'expression genique et des interactions cellulaires a la formation d'un embryon multicellulaire organise. Les participants sont inities a une variete de modeles embryonnaires, incluant des organismes modeles genetiques tels que Drosophila, C. elegans, la souris et le poisson zebre, ainsi que des modeles classiques d'embryologie experimentale tels que le Xenopeet le poulet. Ces modeles sont etudies a l'aide de methodologies et de technologies de pointe. Les etudiants peuvent beneficier a la fois d'un enseignement theorique (10 jours de cours magistraux) et d'une formation experimentale (3 semaines de travaux pratiques) portant sur les aspects normaux et pathologiques du developpement. À noter que le module de cours magistraux de 10 jours peut etre suivi seul ou en combinaison avec le module de travaux pratiques. Les cours magistraux sont dispenses par des chercheurs de renommee internationale et abordent des thematiques telles que la specification et la differenciation cellulaires, la biologie des cellules souches, la morphogenese et l'organogenese, la signalisation intracellulaire, ainsi que la regulation de l'expression genique au cours du developpement. Le cycle de conferences se conclut par un congres scientifique international de 1,5 jour consacre a la morphogenese, offrant a de nombreux participants l'opportunite d'assister a leur premiere conference scientifique. OBJECTIF(S) L'objectif est de familiariser les etudiants avec les concepts recents de la Biologie du developpement en soulignant plus particulierement leur importante contribution aux domaines des cellules souches et des sciences cliniques. Differents champs de la Biologie du developpement sont presentes en relation avec les cellules souches, non seulement a travers la diversite des modeles embryonnaires mais aussi a travers les approches recentes developpees dans ces domaines (approches a grande echelle, modelisation mathematique, approches biophysiques?). Plus d informations More details... Published on 06-06-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Helene Martel-Massignac (BDD)

Monday 05 October 2026 0:00

Neurepiomics 2026


Founded by leading researchers, Professors Stephanie Debette and Sudha Seshadri, this annual event brings together a vibrant global community for an immersive, cross?disciplinary training experience. More details... Tags: Seshadri Published on 05-06-2026

	I. Cerveau et de la Moelle Institut du cerveau

Friday 30 October 2026 11:30

72 female scientists honored on the Eiffel Tower: spotlight on Denise Albe-Fessard
Philippe Vernier | Charge de mission Institut NeuroPSI


More details... Published on 04-06-2026

	NeuroPSI Salle de conference Albe-Fessard

Friday 09 October 2026 11:30

Evolution, Development, and Function of Motor Circuits.
Lora Sweeney | Assistant Professor, Institute of Science and Technology Austria (ISTA)


More details... Tags: Institute of Science and Technology Austria, Ista, Lora, International Seed Testing Association Published on 04-06-2026

	NeuroPSI Salle de conference Albe-Fessard

Thursday 03 September 2026 9:00

Challenges from Longitudinal Data


The first day will be devoted to presentations by international experts on methods, applications and issues related to longitudinal data. The second day will offer practical tutorials around open-source software in R and Python, including Leaspy, JMbayes2, lcmm and saemix. More details... Tags: Social research, Design of experiments, Longitudinal study, Nursing research, Observational study Published on 02-06-2026

	I. Cerveau et de la Moelle Day 1 - Thursday September 3, 2026

Monday 29 June 2026 17:15

Exploration of Aqueous Biomarkers from Retinoblastoma to Uveal Melanoma
Jesse Berry


Over the past decade, aqueous humor liquid biopsy has emerged as a transformative tool in ocular oncology, enabling minimally invasive molecular profiling of intraocular tumors from small-volume aqueous samples. Pioneered in retinoblastoma, this work demonstrated that cell-free DNA and ctDNA correlate with disease activity and prognosis, and that RB1 mutations can be reliably tracked across treatment - findings that established the clinical foundation for the LBSeq4Kids platform. Serial aqueous sampling has since proven valuable for guiding therapy and identifying patients at risk for metastatic progression without systemic biopsy. Now, this liquid biopsy framework is being extended to uveal melanoma, where modeled aqueous humor protein concentrations are opening a new avenue for biomarker discovery and non-invasive disease characterization. More details... Tags: Biomarkers, Rare diseases, Medical signs, Pediatric cancers, Melanoma, Uveal melanoma, Cancer biomarker, Retinoblastoma, Circulating tumor DNA, Liquid biopsy, Uvea, Eye neoplasm Published on 30-05-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Helene Martel-Massignac (BDD)

Friday 26 June 2026 11:45

Biomolecular Condensates at the Nuclear Envelope: From Mechanism to Therapeutic Modulation
Christian Schlieker


Invite par l'equipe Palancade, Christian Schlieker (Department of Molecular Biophysics and Biochemistry, Yale University, USA) presentera un seminaire de l'Institut Jacques Monod sur le theme : Biomolecular Condensates at the Nuclear Envelope: From Mechanism to Therapeutic Modulation Christian started his scientific training as an undergraduate at the University of Bonn in Germany, with a research stay at the University of New South Wales in Sydney, Australia. He then earned his Ph.D. in the laboratory of Dr. Bernd Bukau at the Center for Molecular Biology (ZMBH) of Heidelberg University, where he used biochemical and biophysical approaches to uncover how Clp/HSP100 AAA+ ATPases counteract proteotoxic stress. Christian continued his training as an EMBO postdoctoral fellow with Dr. Hidde Ploegh at Harvard Medical School and the Whitehead Institute/MIT, where he explored the ubiquitin-proteasome system and discovered a novel role for a ubiquitin-like modifier in RNA biology. Christian joined the Department of Molecular Biophysics and Biochemistry at Yale University in 2009, where he is currently Professor and Director of Undergraduate Studies, with a secondary appointment in the Department of Cell Biology. He is a recipient of the NIH Director's New Innovator Award and has served on the scientific advisory board of the Dystonia Medical Research Foundation and reviewed for the NIH, the Department of Defense, the German Excellence Initiative, ANR and the European Research Council, among others. At Yale, he has chaired the Committee on Majors for Yale College and currently serves on the Advisory Board of the Yale Center for Molecular Discovery. Starting in July 2026, he will chair the Department of Molecular Biophysics and Biochemistry. Brief synopsis We explore how cells build and safeguard two the nuclear envelope and the endoplasmic reticulum. Our work focuses on how disruptions in membrane organization and phase separation drive the formation of aberrant condensates that are increasingly implicated in neurological disease. To tackle these questions, we develop and apply new tools that allow us to probe and modulate these processes across scales, from the dynamics of individual proteins and condensates to genome-wide functional screens. By integrating cell biology, biochemistry, and computational approaches with patient-derived and animal model systems, we aim to uncover fundamental principles of cellular organization and translate these discoveries into novel therapeutic strategies for movement disorders and related conditions. We recently developed a high-content platform and computational pipeline to screen modulators of nuclear condensates across chemical and genetic space. This effort identified novel players in nuclear condensates formation, along with small molecules that modualte proteotoxic condensates. Application of the platform in a genome-wide CRISPR knockout screen revealed strong enrichment of candidate genes linked to primary microcephaly and related neurodevelopmental disorders, pointing to condensate dysregulation as a shared molecular axis across disease. A complementary line of work asks how the nuclear pore complex itself contributes to protein quality control. Co-translational folding allows nascent proteins to begin folding as they are synthesized, reducing the risk of aggregation and avoiding energy-intensive unfolding steps. We propose that karyopherins and flexible FG-nucleoporins not only safeguard the nuclear permeability barrier but also generate a supportive environment - a folding phase? - that promotes correct folding of proteins entering the nucleus. This perspective offers new insight into how disruptions in nuclear transport and protein quality control may contribute to neurological disease. Together, these efforts may inform biotechnological advances in protein stability and targeted therapeutics for diseases of disrupted folding. Selected publications Prophet SM, Rampello AJ, Niescier RF, Gentile JE, Mallik S, Koleske AJ, Schlieker C: Atypical nuclear envelope condensates linked to neurological disorders reveal nucleoporin-directed chaperone activities. Nat Cell Biol 2022, 24:1630-1641. Poch D, Mukherjee C, Mallik S, Todorow V, Kuiper EFE, Dhingra N, Surovtseva YV, Schlieker C: Integrative Chemical Genetics Platform Identifies Condensate Modulators Linked to Neurological Disorders. bioRxiv 2025, doi:10.1101/2025.06.07.658469. Rampello AJ, Laudermilch E, Vishnoi N, Prophet SM, Shao L, Zhao C, Lusk CP, Schlieker C: Torsin ATPase deficiency leads to defects in nuclear pore biogenesis and sequestration of MLF2. J Cell Biol 2020, 219:e201910185. Mallik S, Poch D, Burick S, Schlieker C: Protein folding and quality control during nuclear transport. Curr Opin Cell Biol 2024, 90:102407. More details... Tags: Organelles, Proteins, Membrane biology, Cell nucleus, Biomolecular condensate, Cell biology, Proteasome, Ubiquitin, Nuclear envelope, Chaperone, Endoplasmic reticulum, Nuclear pore complex Published on 23-05-2026

	Institut Jacques Monod Institut Jacques Monod Salle Francois Jacob, 15 rue Helene Brion, Paris, France

Friday 26 June 2026 11:00

Titre à venir
Seminaire du comite EGO


More details... Tags: Comite Creek Published on 22-05-2026

	NeuroPSI Salle de conference Albe-Fessard

Friday 30 October 2026 9:00

LabEx Milieu Interieur Annual Meeting 2026


Invited by: Darragh Duffy 30th OCTOBER 2026 \| INSTITUT PASTEUR \| FRANCE We are happy to announce the 2026 yearly meeting of Milieu Interieur LabEx Join un on the morning of the 30th of October at 9am at ... More details... Tags: Corruption in France, Organized crime in France Published on 22-05-2026

	Institut Pasteur Batiment: Duclaux Salle: Amphitheatre Duclaux

Monday 06 July 2026 0:00

DIF Day 2026


Les inscriptions pour le DIF day 2026 sont ouvertes ! Rendez-vous sur le site d'inscriptions pour pouvoir y participer : https://sites.google.com/view/dif2026/accueil_2026?authuser=0 More details... Published on 21-05-2026

	Institut Jacques Monod Institut Jacques Monod Amphitheatre Buffon, 15 rue Helene Brion, Paris, France

Thursday 15 October 2026 0:00

Seminaire Sharon Tooze (titre a venir)
Sharon Tooze


More details... Tags: Tooze, Titre Published on 19-05-2026

	Institut Cochin Salle Rosalind Franklin

Thursday 24 September 2026 12:00

REPORTE - Investigating Plasmodium myosins to identify antimalarial targets
Julien ROBERT-PAGANIN, UMR144, Institut Curie, Paris


More details... Tags: Malaria, Plasmodium, Antimalarial medication Published on 19-05-2026

	Institut Cochin -

Thursday 24 September 2026 12:00

Investigating Plasmodium myosins to identify antimalarial targets
Julien ROBERT-PAGANIN, UMR144, Institut Curie, Paris


More details... Tags: Malaria, Plasmodium, Antimalarial medication Published on 17-05-2026

	Institut Cochin -

Thursday 25 June 2026 15:30

Silencing the Past ? Enabling the Future: HUSH-Mediated Regulation of Retroelements
Paul J Lehner


Abstract Retrotransposition - the reverse flow of genetic information from RNA to DNA provides the major route by which new genetic material enters our genome, with retroelements comprising over 40% of human DNA. This process drives innovation but threatens genome integrity, demanding effective regulation. Our discovery of the Human Silencing Hub (HUSH) revealed a genome-wide transcriptional immunosurveillance system that detects and epigenetically silences invading DNA. How HUSH distinguishes self from invading DNA was unclear. We found that HUSH discriminates ?self' from ?non-self' based on cellular introns: The majority of cellular genes are intron-containing, while RNA-derived retroelements are intronless, marking their cDNA as foreign. This intron-based recognition mechanism uncovers an unexpected innate immune surveillance system that protects the genome from the reverse flow of genetic information. Our ongoing work on HUSH-mediated epigenetic repression will be further discussed. More details... Tags: Molecular biology, Non-coding DNA, RNA splicing, DNA, Mobile genetic elements, Intron, Retrotransposon, RNA, Human genome, Complementary DNA, Transposable element, Epigenetics Published on 14-05-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie

Friday 26 June 2026 10:00

Mechanoregulation of Cytotoxic Lymphocyte Function
Morgan Huse


I trained as a structuralbiologist/peptide chemist, with John Kuriyan and Tom Muir at Rockefeller University, before carrying out postdoctoral research with Mark Davis and Stanford. There, I became interested in the structure and function of immune cell-cell interactions. I joined the Immunology Program at Memorial Sloan Kettering Cancer Center in 2007. My lab has primarily focused on the cytotoxic immune synapse, which is the specialized junction used by cytotoxic lymphocytes to destroy infected or transformed target cells. Over the past decade, we have become particularly interested in the mechanobiology of this interface, in particular how physical forces and mechanical properties shape its potency and specificity. My talk will address the role of lymphocyte mechanosensing in anti-tumor immune responses. More details... Tags: Immune system, Lymphocyte, Immunological synapse, T cell Published on 08-05-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie

Tuesday 30 June 2026 9:30

Single-molecule mechanics of eukaryotic and bacterial SMC complexes
Maxim Molodtsov


Structural Maintenance of Chromosomes (SMC) complexes are conserved molecular machines that help organize genomes in organisms ranging from bacteria to humans. They perform two essential tasks: they establish DNA-DNA interactions and extrude DNA loops, thereby shaping chromosome architecture and supporting faithful chromosome segregation. In this talk, I will discuss recent single-molecule studies from our group that reveal how these machines work under force. Using optical tweezers combined with fluorescence microscopy, we directly measure how strongly individual SMC complexes interact with DNA while visualizing their activity. We find that cohesin and condensin can form highly stable DNA connections capable of resisting the forces generated during cell division. By contrast, cohesin-mediated loop extrusion depends on much weaker and more dynamic DNA interactions, allowing loops to be readily remodelled. Comparisons with bacterial SMC complexes show that these machines can be stronger and more efficient loop extruders than their eukaryotic counterparts. Together, these findings suggest that SMC complexes have evolved different mechanical properties to match their specific roles in chromosome folding, maintenance, and segregation. More details... Tags: Mitosis, Cell cycle, Nuclear organization, Condensin, Cohesin, Loop extrusion, SMC protein, Chromosome, DNA, Chromosome condensation Published on 08-05-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie

Monday 16 November 2026 0:00

8eme edition - Biologie Cellulaire et Cancer


Le 8e cours «?Biologie cellulaire et cancer»?explorera comment les formes biologiques emergent a differentes echelles, de l'organisation intracellulaire jusqu'aux tissus et aux organismes entiers. Il mettra l'accent sur des processus cellulaires cles tels que la dynamique du cytosquelette et le trafic intracellulaire, et sur la maniere dont ces processus faconnent des structures cellulaires complexes. Le cours abordera egalement la formation de patterns, la morphogenese et les comportements collectifs des cellules a l'echelle des tissus, dans le contexte de la mecanobiologie et de la biologie du developpement. More details... Published on 07-05-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Helene Martel-Massignac (BDD)

Tuesday 07 July 2026 11:00

Harnessing Viral Mimicry in Cancer Vaccines
Nicolas VABRET


Despite advances in mRNA-based cancer vaccines, therapeutic responses remain limited by poorly immunogenic tumors that fail to support effective T cell infiltration, expansion, and function. Epigenetic therapies can enhance tumor immunogenicity by reactivating transposable elements (TEs), triggering innate sensing of immunogenic nucleic acids through a process known asviral mimicry.In this seminar, I will discuss how the DNA methyltransferase inhibitors induces viral mimicry in preclinicaltumourmodels, leading to type I interferon responses, enhanced antigen presentation, and remodeling of the immunosuppressive tumor microenvironment. This response depends on cancer-intrinsic nucleic acid sensors and supports the expansion and function of vaccine antigen-specific T cells within tumors.Together, these findings identify viral mimicry as a strategy to license therapeutic cancer vaccination and improve anti-tumor immunity. More details... Tags: Immunology, Oncology, Immune system, Biotechnology, Immunogenicity, Cancer vaccine, Antigen, Tumor microenvironment, Glioma 261, Cancer immunotherapy Published on 06-05-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e

Monday 09 November 2026 13:00

Allostery and brain science, a tribute to Jean-Pierre CHANGEUX


Invited by: Pierre-Jean Corringer More details... Tags: Jean-Pierre Changeux, Neuroscientists, Allosteric regulation, Jean-Pierre, Ruth Nussinov, DehaeneChangeux model Published on 30-04-2026

	Institut Pasteur Batiment Duclaux, salle Amphitheatre,

Monday 06 July 2026 11:30

TBA
Dr Jun Nagai | Riken Center for brain science


Invited by: CIRB-College de France More details... Published on 29-04-2026

	College de France au College de France Salle D2 - 11 place Marcelin Berthelot - 75005 Paris

Tuesday 30 June 2026 11:30

Re-wiring the brain vasculature in health and disease
Dr Nicolas Renier | ICM


Invited by: CIRB-College de France More details... Published on 29-04-2026

	College de France au College de France - Salle D2 -11 place Marcelin Berthelot - 75005 Paris

Thursday 24 September 2026 12:00

EM tomography and membrane remodeling


EM tomography and membrane remodeling More details... Tags: Medical imaging, Tomography, Crista, Volumetric Electron Microscopy Published on 29-04-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie

Thursday 02 July 2026 12:00

Unlocking the BloodBrain Barrier during Glioblastoma progression
Kevin Boye


More details... Tags: Boye, Hans Boye, Come, Thou Fount of Every Blessing Published on 29-04-2026

	Centre de Recherche des Cordeliers Amphi Gustave Roussy

Wednesday 08 July 2026 11:30

Gliding Motion of Diatoms: Motors, Filaments, and Dynamic Trajectory Control
Stefan Diez


Raphid diatoms exhibit rapid gliding motility with remarkable directional flexibility, yet the underlying mechanisms remain poorly understood. Using Craspedostauros australis as a model, we combine phylogenomics, live-cell imaging, and high-resolution microscopy to dissect both force generation and trajectory control. We find that raphe-associated actin bundles do not show directional turnover, arguing against a direct role of actin dynamics in force production. Instead, we identify diatom-specific myosins (CaMyoB-D) that display coordinated movement during gliding, consistent with a motor function. At the cellular level, diatoms dynamically modulate their trajectories by switching between one- and two-raphe contact with the substrate. This switching controls path curvature, with single-raphe gliding producing curved paths and dual-raphe gliding resulting in straighter motion. Together, our results suggest a mechanism in which myosin-driven force generation is coupled to dynamic regulation of cell-substrate contact, enabling flexible navigation in complex environments. More details... Tags: Protein families, Actin, Autoantigens, Myosin, Diatom, Gliding motility Published on 24-04-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie

Thursday 25 June 2026 12:00

The many faces of doxorubicin and how to improve it for new cancer therapies
Sjaak Neefjes


Anthracyclines like doxorubicin are still cornerstones in the treatment of a series of tumors. They should act by poisoning topoisomerase II causing DNA double stranded breaks. However, they also evict histones at defined sites in chromatin. We chemically separated these two activities to show that histone eviction was the most cytotoxic activity. Doxorubicin variants acting through histone eviction are active cancer drugs but have lost various toxic side effects including dose-dependent cardiotoxicity. These variants can still be used in the treatment of relapsed cancer patients and can strongly improve their overall survival. New activities in old cancer drugs can thus be explored to control toxicities, allow chronic treatment and improve the quality of life of cancer survivors. More details... Tags: Anthracyclines, Antineoplastic drugs, Doxorubicin, Teratogens, Anthracycline, Chemotherapy, Cardiotoxicity, Histone, CytRx, Zoptarelin doxorubicin Published on 24-04-2026

	Centre de Recherche des Cordeliers Amphi Gustave Roussy

Monday 21 September 2026 0:00

Biologie des Systemes du Cancer | 9e edition


L heterogeneite observee entre les tumeurs de differents patients, et meme entre les cellules cancereuses d'un meme patient, complique considerablement le developpement de traitements. La medecine « personnalisee » ou « de precision » vise a surmonter ce probleme en proposant un traitement adapte a chaque patient, en fonction de son profil genetique individuel et de la signature moleculaire de sa tumeur. Cet objectif ambitieux necessite une caracterisation moleculaire approfondie du cancer chez le patient, a l'aide de technologies a haut debit et de techniques d'imagerie avancees. Beaucoup de donnees multi-echelles sur le cancer deviennent disponibles, mais elles restent encore largement sous-exploitees pour elucider les mecanismes sous-jacents et ainsi guider la stratification des patients et le choix des traitements. L'analyse integrative multimodale des donnees omiques et cliniques offre un fort potentiel pour elucider les bases moleculaires des differents types de cancer. L'integration multimodale des donnees sur la maladie est particulierement prometteuse pour mettre en evidence les relations complexes entre les mecanismes moleculaires qui contribuent collectivement a la maladie. More details... Published on 18-04-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Helene Martel-Massignac (BDD)

Monday 28 September 2026 0:00

Developpement amp; Cancer - 16e edition


Le cours est dedie aux connaissances les plus actuelles articulant la biologie du developpement et l etude cellulaire et moleculaire des cancers. Les cretes neurales et les melanomes, depuis leur formation jusqu a leur migration (metastases), ainsi que les cancers pediatriques d'origine embryonnaires tels que les medulloblastomes et neuroblastomes sont pris comme exemples. Le cours beneficie d une approche multidisciplinaire a multiples echelles (embryologie sur des modeles varies, biophysique, biologie cellulaire, transcriptomique, imagerie...). Il aborde egalement des approches therapeutiques et ainsi que la prise en compte des 3R en recherche avec l'invitation des chercheurs developpant des organoides et des modeles animaux alternatifs. Le cours est ponctue par des tables rondes sur les carrieres dans le milieu academique ou dans l industrie,sur la publication d articles scientifiques ainsi que sur l ethique en experimentation animale.Des sessions posters de doctorants sont egalement organises et des prix pour les meilleurs posters seront decernes par les participants aux cours. More details... Published on 10-04-2026

	Institut Curie Centre de recherche - Orsay - Amphitheatre du Batiment 111

Thursday 25 June 2026 10:00

Adjusting the timing of mammalian development.
Aydan Karslioglu


Pluripotency provides the foundation of embryonic development and regenerative medicine. Pluripotency is also remarkably dynamic, as it can alternate between different states and can be promptly resolved to allow lineage specification. As such, e mbryonic development relies on stem cell function in balance with differentiation. We investigate how this balance is maintained in coordination with the environment and the protective measures the embryos take at times of scarcity. Our mission is to decode the process of dormancy and identify the genetic, epigenetic, and metabolic mechanisms that govern this fascinating phenomenon. More details... Tags: Developmental biology, Biotechnology, Cell biology, Stem cells, Cloning, Cellular differentiation, Cell potency, Adult stem cell Published on 09-04-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Helene Martel-Massignac (BDD)

Monday 29 June 2026 11:00

"Neuromodulation of Brain States"
Luis DELECEA | Depart of Psychiatry & Behavorial Sciences Stanford University School of Medicine


The arousal construct underlies a spectrum of behaviors that include sleep, exploration, feeding, sexual activity and adaptive stress. Pathological arousal conditions include stress, anxiety disorders, and addiction. In the past few years we have used optogenetics to interrogate neuronal circuits underlying transitions between arousal states. In particular, I will talk about two new circuits identified in our laboratory: one predicts the onset and duration of REM sleep with unprecedented precision; another induces sleep in response to inflammatory cytokines. I will also present a novel method that displays cortex-wide fluctuations in membrane voltage using TEMPO imaging. Finally, I will discuss noninvasive neuromodulation methods for sleep intervention. More details... Tags: Neurophysiology, Neuromodulation, Rapid eye movement sleep, Brain Published on 08-04-2026

	I. Cerveau et de la Moelle Institut du cerveau

Monday 21 September 2026 0:00

Conference Jacques Monod - The mechanistic and evolutionary basis of programmed DNA elimination


The Conference Jacques Monod » The mechanistic and evolutionary basis of programmed DNA elimination» will take place fromMonday, September 21, 2026 toFriday, September 25, 2026 in Roscoff (Bretagne, France). Abstracts submission deadline :Tuesday, May 5, 2026 Deadline for payment of registration fees :July 2, 2026 Deadline for return of completed forms :July 2, 2026 Registration and abstract submission website Beyond mutations, the genetic content of an organism is generally constant across cells throughout development. Programmed DNA elimination (PDE) - a process in which specific cell lineages lose DNA segments or whole chromosomes - represents is a striking deviation to this principle. PDE is widespread in eukaryotes and plays roles in a variety of cellular processes, including gene silencing, germline differentiation, genome defence, and non-Mendelian inheritance. It manifests in diverse biological contexts, including the formation of germline-limited genomes, meiotic elimination of parental chromosomes, and sex determination via X-chromosome loss. In recent years, it has become increasingly clear that PDE occurs across a wide range of phylogenetic groups, and involves diverse mechanisms. These findings underscore the overlooked plasticity of genome integrity, and reveal significant gaps in our understanding of why PDE has evolved repeatedly and is maintained across the Tree of Life. This conference is designed to present the latest research on the mechanisms and evolution of PDE - from the molecular pathways that control genome stability and chromosome segregation, to genomic conflictsand the long-term evolutionary consequences of PDE on population dynamics and species diversification.We also welcome researchers studying related phenomena, such as meiotic drive, B chromosomes, and those that work on the mechanisms and regulation of genome stability, chromosome segregation and germline development. The meeting will address the following key topics: Mechanisms and regulation of genome stability and instability Mechanisms of chromosome segregation and missegregation Genomic conflicts Evolutionary dynamics of programmed DNA elimination More details... Tags: Evolutionary biology, Molecular genetics, Molecular evolution, Cell cycle, Meiosis, Mutation, Intragenomic conflict Published on 28-03-2026

	Institut Jacques Monod Roscoff, Roscoff, France

Monday 16 November 2026 0:00

Ctrl+Epi+Edit, Engineering the Epigenome


Epigenome editing is a rapidly emerging field that has the potential to revolutionise genomic medicine by offering new ways to precisely program gene expression and treat a range of diseases. Precision control of the epigenome and gene activity is further unlocking key mechanistic insights into a wide variety of molecular and cellular processes. The potential of epigenome editing technologies for both research and therapeutic applications has thus led to widespread excitement over the last five years, in areas ranging from neurobiology, to high-throughput (epi)genomics to agriculture. As the technologies continue to emerge and the epigenome editing field begins to coalesce, we feel now is the time to bring interdisciplinary experts and leaders in the field together. This will enable, for the first time, epigenome editors and related disciplines to collectively discuss the technology, its applications and ethics, and the exciting scientific insights being generated. Such a symposium will help to accelerate progress in this field by facilitating collaborations between researchers and providing a platform for the dissemination of new discoveries and techniques. It will also help to raise broader awareness of this exciting emerging science and its potential to transform precision medicine. Time and Place The meeting will take place fromNovember 16-17atInstitut Jacques Monodin the heart of Paris, France We will have two half day sessions, and a poster session over cocktails and light bites Key Dates Abstract Submission:October 1, 2026 Registration:November 9, 2026 Invited Speakers ? Gabriella Ficz (QMUL, UK) ? Charles Gersbach (Duke University, USA) ? Jamie Hackett (EMBL Rome, Italy) ? Jake Harris (Cambridge University, UK) ?Angelo Lombardo (San Raffaele University, Italy) ? Reini Luco (Institut Curie, France) ?Mariane Rots (UMCG, Netherlands) ?Edda Schulz (MPI Berlin, Germany) ?Stefan Stricker (Helmholtz Munich, Germany) More speakers will be selected from abstracts! You can find all the informations regarding the symposium, the registration and abstract submission here Flyer of the event: here More details... Tags: Epigenetics, Epigenome editing, Edit, Epigenome, Genome editing, Omics Published on 10-03-2026

	Institut Jacques Monod Institut Jacques Monod Amphitheatre Buffon, 15 rue Helene Brion, Paris, France

Thursday 15 October 2026 12:00

Title to come
Jeremie Gautheron


More details... Tags: Jeremie, Jeremi Published on 06-03-2026

	Centre de Recherche des Cordeliers

Thursday 02 July 2026 9:00

The 11th edition of Start-me up on July 2 et 3, 2026


Invited by: Jong Eun Ihm Start-meup? is an annual two-day event that explores the latest trends in the life sciencesand health innovation ecosystem while guiding participants through the startup creation journey. This year’s expert talks session focuses on how ... More details... Tags: Entrepreneurship, Business incubators, Private equity, Startup company, Innovation Published on 04-03-2026

	Institut Pasteur Batiment: Centre Francois Jacob Salle: Auditorium

Thursday 08 October 2026 12:00

Title to come
Yasmine Belkaid


More details... Tags: Pasteur Institute, Yasmine Belkaid, Yasmin, Aboubakr Belkaid, Lurie Prize in Biomedical Sciences Published on 04-03-2026

	Centre de Recherche des Cordeliers

Thursday 24 September 2026 9:00

CRC Scientific Day 2026


Every year, the Centre de Recherche des Cordeliers organises a scientific day where its young researchers, students and post-docs present their work.Prestigious speakers are also invited to take part.This year, we will be welcoming:This event is open to the entire scientific community. More details... Tags: Inquiry, Observation, Science, European Research Council Published on 27-02-2026

	Centre de Recherche des Cordeliers

Monday 14 September 2026 14:00

EMBO Workshop The complexity of mycobacterial infections: From research to real-world impact


Invited by: Giulia Manina Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains one of the deadliest infectious diseases worldwide. Meanwhile, non-tuberculous mycobacteria (NTM) are an increasing global health concern. NTM infections often resemble TB clinically, which can lead to ... More details... Tags: Acid-fast bacilli, Bacterial diseases, Tuberculosis, Pathogenic bacteria, Infectious causes of cancer, Nontuberculous mycobacteria, Mycobacterium, Mycobacterium fortuitum, Mycobacterial cervical lymphadenitis Published on 26-02-2026

	Institut Pasteur Batiment CIS, salle ,

Thursday 29 October 2026 9:00

Immune variability across the life course


Invited by: Darragh Duffy Thursday 29th Oct 26 \| Institut Pasteur KEYNOTE SPEAKERS ? Prof. Yasmine Belkaid President of the Institut Pasteur (Paris), Professor Yasmine Belkaid is an internationally recognized immunologist specializing in host-microbiota interactions and tissue immunity. ... More details... Tags: Pasteur Institute, Yasmine Belkaid, Microbiology, Microbiomes, Bacteriology, Louis Pasteur, Variability, Human microbiome Published on 24-02-2026

	Institut Pasteur Batiment: Duclaux

Tuesday 30 June 2026 11:00

TBA
| LJP


TBA More details... Tags: LJP, National Youth Council of Latvia, Liberty and Justice Party Published on 11-12-2023

	Laboratoire Jean Perrin Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407

From Tissues to Trials: Designing and Analyzing Biomarker-Driven Clinical Trials Susan Halabi | Duke Cancer Institute, Durham, USA

Nuclear nutrient sensing signaling of Class 3 PI3K in metabolic homeostasis Ganna Panasyuk | INEM, equipe Mecanismes de detection des nutriments

Toxicologie medico-legale : applications historiques Philippe Charlier and Laurene Dufayet | LAAB/UVSQ - Musee Quai Branly and UMR-S 1144 Optimisation Therapeutique en Neuropharmacologie

Driver mutations and immune microenvironment in acute myeloid leukemia Antonio CURTI

IMAGING ACROSS SCALES ? CATCHING CONCURRENT ORGANELLE DYNAMICS IN LIVING CELLS AND TISSUES

Cryo-EM and cryo-ET of membrane remodeling in autophagy and endolysosomes

CANCELLED : Innovation en imagerie cellulaire et tissulaire Florence Niedergang, Yannick Allanore, Gilles Renault, Mirko Minini, Edouard Lecarpentier, Pierre Bourdoncle, Alain Schmitt

Enzymatic Syntheses of Base-Modified and Hypermodified Nucleic Acids for Chemical Biology, Bioanalysis and Aptamer Selection

Vagal Signaling in Psychiatric Disorders: Toward a Reverse-Translational Neuroscience of BrainBody Interactions Prof. Julian Koenig | University of Cologne, Germany

eIF2alpha kinase HRI in innate immunity, proteostasis and mitochondrial stress Damien ARNOULT

DSCB Seminar - Dr. Agnete Kirkeby, University of Copenhagen, Denmark - Modelling and repairing the human brain with pluripotent stem cells

DSCB Seminar - Dr. Steffen Rulands, Ludwig Maximilian University of Munich, Germany - Emergent dynamics in cells and tissues: a statistical physics approach

Largescale multiomic modelling of human brain reveals metabolic adaptation that precedes bioenergetic collapse in Alzheimer?s disease Scott AYTON

How do cells build complicated organelles? Jordan Raff

Postdoc Appreciation Week Symposium

TBA Dr Bo Gao | School of Biomedical Sciences

TBA Dr Raffaella Tonini | Institut Italien de Tecnologie

International conferences Integrative Microbiome Program at Pasteur

17e edition - Biologie du Developpement

Neurepiomics 2026

72 female scientists honored on the Eiffel Tower: spotlight on Denise Albe-Fessard Philippe Vernier | Charge de mission Institut NeuroPSI

Evolution, Development, and Function of Motor Circuits. Lora Sweeney | Assistant Professor, Institute of Science and Technology Austria (ISTA)

Challenges from Longitudinal Data

Exploration of Aqueous Biomarkers from Retinoblastoma to Uveal Melanoma Jesse Berry

Biomolecular Condensates at the Nuclear Envelope: From Mechanism to Therapeutic Modulation Christian Schlieker

Titre à venir Seminaire du comite EGO

LabEx Milieu Interieur Annual Meeting 2026

DIF Day 2026

Seminaire Sharon Tooze (titre a venir) Sharon Tooze

REPORTE - Investigating Plasmodium myosins to identify antimalarial targets Julien ROBERT-PAGANIN, UMR144, Institut Curie, Paris

Investigating Plasmodium myosins to identify antimalarial targets Julien ROBERT-PAGANIN, UMR144, Institut Curie, Paris

Silencing the Past ? Enabling the Future: HUSH-Mediated Regulation of Retroelements Paul J Lehner

Mechanoregulation of Cytotoxic Lymphocyte Function Morgan Huse

Single-molecule mechanics of eukaryotic and bacterial SMC complexes Maxim Molodtsov

8eme edition - Biologie Cellulaire et Cancer

Harnessing Viral Mimicry in Cancer Vaccines Nicolas VABRET

Allostery and brain science, a tribute to Jean-Pierre CHANGEUX

TBA Dr Jun Nagai | Riken Center for brain science

Re-wiring the brain vasculature in health and disease Dr Nicolas Renier | ICM

EM tomography and membrane remodeling

Unlocking the BloodBrain Barrier during Glioblastoma progression Kevin Boye

Gliding Motion of Diatoms: Motors, Filaments, and Dynamic Trajectory Control Stefan Diez

The many faces of doxorubicin and how to improve it for new cancer therapies Sjaak Neefjes

Biologie des Systemes du Cancer | 9e edition

Developpement amp; Cancer - 16e edition

Adjusting the timing of mammalian development. Aydan Karslioglu

"Neuromodulation of Brain States" Luis DELECEA | Depart of Psychiatry & Behavorial Sciences Stanford University School of Medicine

Conference Jacques Monod - The mechanistic and evolutionary basis of programmed DNA elimination

Ctrl+Epi+Edit, Engineering the Epigenome

Title to come Jeremie Gautheron

The 11th edition of Start-me up on July 2 et 3, 2026

Title to come Yasmine Belkaid

CRC Scientific Day 2026

EMBO Workshop The complexity of mycobacterial infections: From research to real-world impact

Immune variability across the life course

TBA | LJP

From Tissues to Trials: Designing and Analyzing Biomarker-Driven Clinical Trials
Susan Halabi | Duke Cancer Institute, Durham, USA

Nuclear nutrient sensing signaling of Class 3 PI3K in metabolic homeostasis
Ganna Panasyuk | INEM, equipe Mecanismes de detection des nutriments

Toxicologie medico-legale : applications historiques
Philippe Charlier and Laurene Dufayet | LAAB/UVSQ - Musee Quai Branly and UMR-S 1144 Optimisation Therapeutique en Neuropharmacologie

Driver mutations and immune microenvironment in acute myeloid leukemia
Antonio CURTI

CANCELLED : Innovation en imagerie cellulaire et tissulaire
Florence Niedergang, Yannick Allanore, Gilles Renault, Mirko Minini, Edouard Lecarpentier, Pierre Bourdoncle, Alain Schmitt

Vagal Signaling in Psychiatric Disorders: Toward a Reverse-Translational Neuroscience of BrainBody Interactions
Prof. Julian Koenig | University of Cologne, Germany

eIF2alpha kinase HRI in innate immunity, proteostasis and mitochondrial stress
Damien ARNOULT

Largescale multiomic modelling of human brain reveals metabolic adaptation that precedes bioenergetic collapse in Alzheimer?s disease
Scott AYTON

How do cells build complicated organelles?
Jordan Raff

TBA
Dr Bo Gao | School of Biomedical Sciences

TBA
Dr Raffaella Tonini | Institut Italien de Tecnologie

72 female scientists honored on the Eiffel Tower: spotlight on Denise Albe-Fessard
Philippe Vernier | Charge de mission Institut NeuroPSI

Evolution, Development, and Function of Motor Circuits.
Lora Sweeney | Assistant Professor, Institute of Science and Technology Austria (ISTA)

Exploration of Aqueous Biomarkers from Retinoblastoma to Uveal Melanoma
Jesse Berry

Biomolecular Condensates at the Nuclear Envelope: From Mechanism to Therapeutic Modulation
Christian Schlieker

Titre à venir
Seminaire du comite EGO

Seminaire Sharon Tooze (titre a venir)
Sharon Tooze

REPORTE - Investigating Plasmodium myosins to identify antimalarial targets
Julien ROBERT-PAGANIN, UMR144, Institut Curie, Paris

Investigating Plasmodium myosins to identify antimalarial targets
Julien ROBERT-PAGANIN, UMR144, Institut Curie, Paris

Silencing the Past ? Enabling the Future: HUSH-Mediated Regulation of Retroelements
Paul J Lehner

Mechanoregulation of Cytotoxic Lymphocyte Function
Morgan Huse

Single-molecule mechanics of eukaryotic and bacterial SMC complexes
Maxim Molodtsov

Harnessing Viral Mimicry in Cancer Vaccines
Nicolas VABRET

TBA
Dr Jun Nagai | Riken Center for brain science

Re-wiring the brain vasculature in health and disease
Dr Nicolas Renier | ICM

Unlocking the BloodBrain Barrier during Glioblastoma progression
Kevin Boye

Gliding Motion of Diatoms: Motors, Filaments, and Dynamic Trajectory Control
Stefan Diez

The many faces of doxorubicin and how to improve it for new cancer therapies
Sjaak Neefjes

Adjusting the timing of mammalian development.
Aydan Karslioglu

"Neuromodulation of Brain States"
Luis DELECEA | Depart of Psychiatry & Behavorial Sciences Stanford University School of Medicine

Title to come
Jeremie Gautheron

Title to come
Yasmine Belkaid

TBA
| LJP