Lundi 18 Mai 2026 0:00

16th 3R meeting


We are happy to announce theopening of registrations for the 16th edition of the French 3R meetingReplication, Recombination, Repair?! The meeting will take place fromMay 18 to 21, 2026, at the Belambra Club Presqu'ile du Ponant,La Grande Motte near Montpellier, France. Please visit the meeting website:https://www.2026.3r-meeting.fr/ Registrations will be open fromJanuary 12, to March 23, 2026. Deadline for abstract submission: 2nd of March 2026 Early birdregistrations fees are proposed until2nd of March 2026as following (tax-free): PhD students and postdocs (shared accommodation): 400 € Researchers, engineers, permanent staff (shared accommodation): 480 € Researchers, engineers, permanent staff (single accommodation): 550 € Sponsors and non-academic participants (without accommodation): 300 € Single accommodation is available in limited numbers and will be allocated on a first-come, first-served basis. Shared accommodation consists of two separate bedrooms and one bathroom. Full pricesafter the 2nd of March 2026 as following: PhD students and postdocs (shared accommodation): 480 € Researchers, engineers, permanent staff (shared accommodation): 560 € Researchers, engineers, permanent staff (single accommodation): 630 € Sponsors and non-academic participants (without accommodation): 300 € Please share this message with anyone who might be interested. We hope to see you all at the meeting! The organizing committee Flyer Plus d'infos... Tags: Academic administration, Postdoctoral researcher Annonce publiée le 29-01-2026

	Institut Jacques Monod Presqu'ile du Ponant, France, Rue Saint-Louis,, La Grande-Motte, France

Lundi 18 Mai 2026 0:00

Regulations post-transcriptionnelles des genes - 8e cours


L'objectif de ce cours est de fournir un apercu global des regulations post-transcriptionnelles de l'expression des genes a differents niveaux, incluant l'epissage, la polyadenylation, les modifications (epitranscriptome), la localisation, la traduction et la degradation des ARN (pre-)messagers. Outre les cours donnes par des experts internationaux dans le domaine, le cours reposera aussi sur la contribution active des participants et leurs interactions avec les orateurs. Chaque participant presentera son projet scientifique (poster, elevator pitch) et sera co-chairman d'un orateur. En plus des longs temps de discussion apres les seminaires, les participants auront l opportunite de rencontrer les intervenants chaque jour autour de pauses cafes et d un dejeuner. Plus d'infos... Annonce publiée le 18-02-2026

	Institut Curie Centre de recherche - Orsay - Amphitheatre du Batiment 111

Lundi 18 Mai 2026 0:00

Radiomique : theorie et pratique - 5e edition


Programme preliminaire : JOUR 1 Session du matin - cours theoriques (en ligne et presentiel) Breve introduction a la radiomique - I. Buvat Revision des concepts de base Planification de la recherche - I. Buvat Approche etape par etape de la conception d hypotheses, de la preparation et de la conservation des donnees, de l evaluation des modeles, etc. Radiomique : extraction de caracteristiques - F. Orlhac Parametres pour le calcul des caracteristiques (discretisation, reechantillonnage spatial), definitions, IBSI, filtres Questions-reponses interactives Session de l apres-midi - travaux pratiques (en presentiel uniquement) Pratique de LIFEx Lecture et manipulation d images, segmentation, extraction de caracteristiques radiomiques, scripting Presentation des projets des participants (facultatif) - session 1 (5 min. par participant) Diner convivial JOUR 2 Session du matin - cours theoriques (en ligne et presentiel) Reproductibilite des caracteristiques radiomiques : necessite d une harmonisation - F Orlhac Defi de la reproductibilite en radiomique, effet du centre et de la population, solutions pour l harmonisation et ComBat Construction d un modele radiomique - J Mullaert Classification vs prediction, curation des donnees, selection des caracteristiques, modeles Questions-reponses interactives Session de l apres-midi - travaux pratiques (en presentiel uniquement) Pratique de Shiny Harmonisation des caracteristiques avec ComBat Pratique de R (ou d un autre environnement d analyse statistique) Curation des donnees, pretraitement, construction d un modele (partie 1) Presentation des projets des participants (facultatif) - session 2 (5 min par participant) JOUR 3 Session du matin - cours theoriques (en ligne et presentiel) Evaluation des modeles - J Mullaert Metriques, strategies de validation croisee, validation externe Interpretation des modeles et rapport d une etude radiomique - I Buvat Effet Clever Hans, outils pour guider la redaction des rapports (CLEAR, METRICS, RQS?) Questions-reponses interactives Session de l apres-midi - travaux pratiques (en presentiel uniquement) Pratique de R (ou d un autre environnement d analyse statistique) Construction d un modele (partie 2), evaluation des performances Utilisation de metriques pour evaluer la qualite d une etude radiomique Retour d information et discussion generale avec les participants Plus d'infos... Annonce publiée le 21-02-2026

	Institut Curie Centre de recherche - Paris

Lundi 18 Mai 2026 9:00

Euro-African Congress on the Valorisation of Microbial Genetic Resources - RGM EuroAfrica


Invite par: Raquel Hurtado Ortiz The first Euro-African french-speaking Congress on the Valorisation of Microbial Genetic Resources will be held in Rabat, Morocco, bringing together European and African scientific research communities, industry representatives, and public policy representatives. Thanks to ... Plus d'infos... Tags: Genetics, Biodiversity, Genetic resources Annonce publiée le 14-04-2026

	Institut Pasteur Salle ,

Lundi 18 Mai 2026 11:00

"Neurocomputational approaches to goal pursuit, productivity, and self-control in the lab and real life"
Cendri HUTCHERSON | Department of Psychology University of Toronto


People sometimes succeed, and often fail, to accomplish what they set out to do. What underlies successful vs. failed goal pursuit? Here, I discuss a number of lines of work from our lab showing how a neurally-informed computational approach can be used to understand a variety of phenomena related to self-control in both laboratory contexts and in real-world behaviors. First, I discuss how a neurocomputational framework can be used to understand not only why some choices (e.g., eating healthy) can feel so difficult, but also how we might make them easier. Next, I will outline recent work in which we apply neurocomputational approaches toward modeling fluctuations in daily cognitive and motivational states to understand why it can sometimes feel so difficult to accomplish our goals in daily life. In both cases, our results point to a novel understanding of the importance of trait and state factors shaping the computational dynamics of evidence accumulation during decision making. Plus d'infos... Tags: Economic growth, Productivity, Motivation Annonce publiée le 26-03-2026

	I. Cerveau et de la Moelle Institut du cerveau

Mardi 19 Mai 2026 10:00

EVH Annual Meeting 2026


The EVH Annual Meeting 2026 will be held at the Marburg Old University. For more information and registration, please click below: Plus d'infos... Tags: Eddie Van Halen, Indo people, Marburg, Meeting, EVH, Peavey EVH Wolfgang Annonce publiée le 18-04-2026

	Institut Pasteur Salle ,

Mardi 19 Mai 2026 11:00

Mechanism of sRNA recognition and regulation by FinO RNA chaperones


Invite par: Felix A. Rey Mark Glover Department of Biochemistry, University of Alberta Seminar Joint with Microbiology External attendees wishing to participate in the seminar are required to contact the following email address dbsc@pasteur.fr in order to obtain access to the ... Plus d'infos... Tags: Non-coding RNA, Nucleic acids, Srna, RNA Annonce publiée le 28-04-2026

	Institut Pasteur Batiment agnes ullmann, salle agnes ullmann,

Mardi 19 Mai 2026 11:45

Paris Postdoc Seminar - Artur Ruppel


Invite par l'Institut Jacques Monod, Artur Ruppel ( Institut Pasteur) presentera un Paris Postdoc seminar sur le theme : Designing minimalistic tissue models: A reductionist approach to dissect collective cell behavior Resume : Living tissues are active materials whose collective behavior emerges from the mechanical properties and interactions of their cellular constituents. Understanding how cell-scale mechanics give rise to tissue-scale phenomena remains challenging due to the inherent complexity of biological systems. This seminar presents a reductionist strategy using micropatterning to create minimal tissue models that isolate specific cellular processes for quantitative study. The first part addresses the mechanics of T1 transitions in tissues, the neighbor exchange events driving tissue remodeling during morphogenesis. Using cell quadruplets on cross-shaped micropatterns, we experimentally measured the effective energy landscape of T1 transitions and validated vertex model predictions, revealing how geometric constraints set energy barriers that active forces must overcome. The second part turns to mechanical heterogeneity in tissues. While cell-to-cell variability is ubiquitous, whether it functions as a driver of collective behavior or merely represents noise remains unclear. Using controlled mixtures of wild-type and vimentin-knockout glioblastoma cells, we systematically investigate how the degree and spatial organization of mechanical heterogeneity shapes tissue mechanics. Plus d'infos... Tags: Developmental biology, Micropatterning, Microtechnology, Morphogenesis Annonce publiée le 30-04-2026

	Institut Jacques Monod Institut Jacques Monod Salle Francois Jacob, 15 rue Helene Brion, Paris, France

Mercredi 20 Mai 2026 9:30

Cytoskeleton club


La prochaine reunion du cytoskeleton club aura lieu mercredi 15 octobre a l’Institut Jacques Monod : Izeta Kankadze (PhD student, Fassier/Nicol's team, Institut de la Vision) presentera «Compartmentalized Second Messenger Signals Contribute to Cytoskeletal Remodeling in Axon Guidance» Veronique MARTHIENS (Researcher, R. Basto's team, Institut Curie) presentera «Brain biomechanics governs mitotic fidelity of embryonic neural stem cells» Plus d'infos... Tags: Developmental neuroscience, Axon guidance, Cytoskeleton, Axon Annonce publiée le 03-10-2025

	Institut Jacques Monod Institut Jacques Monod Salle Francois Jacob, 15 rue Helene Brion, Paris, France

Mercredi 20 Mai 2026 11:30

Novel insights into tissue mechano-adaptation through extracellular matrix sensing
Gisou VAN DER GOOT


Tissues must continuously adapt to mechanical constraints imposed by their extracellular environment. How cells interpret extracellular architecture and translate this information into coordinated changes in cell behavior and matrix turnover remains incompletely understood. Our recent findings identify Capillary Morphogenesis Gene 2 (CMG2) as a key molecular interpreter of extracellular composition and organization that instructs cells. In lymphatic capillaries, CMG2 regulates VEGFR3 signalling and actin-dependent junctional architecture required for fluid uptake. Loss of CMG2 disrupts button junction organization and impairing interstitial fluid clearance, demonstrating how cytoskeletal state transitions can directly control organ-level function. These in vivo observations provide a unifying mechanistic model for several previously unexplained molecular properties of CMG2: CMG2 is a receptor that reads? extracellular ligands reflecting matrix composition and architecture. Ligand engagement instructs distinct cellular responses - actin cytoskeleton reorganization, receptor trafficking, lysosomal degradation of extracellular components. This determines junction organization, tissue permeability, and mechanical resilience. CMG2 emerges as a key component of tissue mechano-adaptation. This integrated view reconciles observations from genetic models, patient mutations, and biochemical studies, and identifies Hyaline Fibromatosis Syndrome, caused by mutations in cmg2, as a disorder of impaired tissue mechano-adaptation. Plus d'infos... Tags: Extracellular matrix, Actin, Matrix, Biophysics, Cell signaling Annonce publiée le 24-04-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre IPGG - 6 rue Jean Calvin, Paris 5e

Mercredi 20 Mai 2026 14:00

Webinaire de l'enseignement - Comment lancer des recherches lors d'une epidemie ? avec Michael Casera


Comment faire face a l'urgence tout en recueillant des donnees de maniere ethique et coordonnee afin de pouvoir ensuite les publier ? Ce webinaire apportera un eclairage concret sur les enjeux du terrain, les ... Plus d'infos... Annonce publiée le 18-04-2026

	Institut Pasteur

Mercredi 20 Mai 2026 14:00

«Comprendre le vivant a l'echelle des proteines»
Guillaume Chevreux


Guillaume Chevreux (plateforme ProteoSeine) va defendre son Habilitation a Diriger les Recherches: «Comprendre le vivant a l'echelle des proteines» La soutenance se tiendra en francais le mercredi 20 mai 2026 a 14h00 en salle Francois Jacob (IJM) en presence du jury compose de : President Mariano A. Ostuni, Professeur, Universite Paris Cite Rapporteurs Sarah Cianferani, Directrice de Recherche, CNRS/Universite de Strasbourg Guillaume van der Rest, Professeur, Universite Paris-Saclay Jerome Lemoine, Professeur, Universite Claude Bernard Lyon Examinateurs Frederic Halgand, Charge de Recherche, Universite Paris-Saclay Chiara Guerrera, Ingenieur de Recherche, Universite Paris Cite Invite Jean-Michel Camadro, Directeur de Recherche Emerite, Universite Paris Cite Plus d'infos... Annonce publiée le 24-04-2026

	Institut Jacques Monod Institut Jacques Monod Salle Francois Jacob, 15 rue Helene Brion, Paris, France

Mercredi 20 Mai 2026 14:00

Webinaire de l'enseignement - Comment lancer des recherches lors d'une epidemie ? avec Michael Casera
Michael Casera


Invite par: Michael Casera Comment faire face a l'urgence tout en recueillant des donnees de maniere ethique et coordonnee afin de pouvoir ensuite les publier ? Ce webinaire apportera un eclairage concret sur les enjeux du terrain, les ... Plus d'infos... Annonce publiée le 04-05-2026

	Institut Pasteur

Mercredi 20 Mai 2026 14:00

Des graisses qui vous veulent du bien : perceptions du gras, sante et plaisirs culinaires
Martine Glorian, Vincent Moriniaux, Christine Coudray, Esther Katz, Nicolas Cesard, Christophe Lavelle | FSI-UFR de Biologie, FL-UFR de Geographie, INRAE, MNHN


Invite par: Martine Glorian pour l'Initiative Alimentation de Sorbonne Universite Martine Glorian (FSI, UFR de Biologie) : Le gras sans prejuges : quelques cles pour commencer ? Vincent Moriniaux (FL, UFR de Geographie) : Les visions du gras, a travers le temps et l'espace ? Christine Coudray (INRAE) Les acides gras furaniques : un tresor cache dans notre assiette ? Esther Katz et Nicolas Cesard (MNHN) Les insectes comestibles : une source de bons lipides ? ? Christophe Lavelle (MNHN) Le gras en cuisine : 1001 facons de sublimer un ingredient essentiel Plus d'infos... Tags: Fat, Dietetics, Food Annonce publiée le 11-05-2026

	Initiative Alimentation de Sorbonne Universite Amphitheatre Herpin du Batiment Esclangon, Campus Pierre et Marie Curie, 4 place Jussieu - 75005

Mercredi 20 Mai 2026 16:30

Titre à venir
Bregeon/Hamdane's lab and Diu Nguyen - Group Leader at Barts Cancer Institute, Queen Mary University of London


TBC soon - stay tuned! Plus d'infos... Tags: St. Bartholomew's, Barts and The London School of Medicine and Dentistry, Queen Mary University of London Annonce publiée le 16-03-2026

	Paris RNA Club Auditorium Gallois - 45 rue d Ulm, 75005 Paris

Mercredi 20 Mai 2026 16:30

Titre à venir
Bregeon/Hamdane's lab and Diu Nguyen


TBC soon - stay tuned! Plus d'infos... Tags: Bregeon, Surnames, Stay Tuned, Diu Annonce publiée le 09-04-2026

	Paris RNA Club Auditorium Gallois - 45 rue d Ulm, 75005 Paris

Mercredi 20 Mai 2026 16:30

cterial dihydrouridine synthases and Decrypter l'ARN dans sa complexite : l'apport du sequencage Nanopore
Bregeon/Hamdane's lab and Anais Mounier - Oxford Nanopore


TBC soon - stay tuned! Plus d'infos... Tags: Nanotechnology, Oxford Nanopore Technologies, Nanopore, Bregeon, Mounier, Stay Tuned, Anas Annonce publiée le 30-04-2026

	Paris RNA Club Auditorium Gallois - 45 rue d Ulm, 75005 Paris

Jeudi 21 Mai 2026 12:00

Investigating Plasmodium myosins to identify antimalarial targets
Julien ROBERT-PAGANIN, UMR144, Institut Curie, Paris


Plus d'infos... Tags: Malaria, Plasmodium, Antimalarial medication Annonce publiée le 23-04-2026

	Institut Cochin Salle Rosalind Franklin

Jeudi 21 Mai 2026 12:00

From tumor tissues to autoimmunity: discovery of regulatory DN1 B cells reveals shared pathways of immune regulation.
Claudia Mauri


Plus d'infos... Tags: Mauri, Claudia, Barrier to the North, He Was Called Holy Ghost Annonce publiée le 27-01-2026

	Centre de Recherche des Cordeliers

Vendredi 22 Mai 2026 10:30

Playing with FIRE: the role of macrophages in development and disease
Dr Clare Pridans | Univ. of Edinburgh


Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 30-01-2026

	College de France au College de France - Salle 2 - 11 place Marcelin Berthelot - 75005 Paris

Vendredi 22 Mai 2026 11:00

Pizz of Science - Title to come


Plus d'infos... Tags: Bregaglia, ItalySwitzerland border, Pizz Gallagiun Annonce publiée le 23-09-2025

	Inst. Bio. Paris Seine 7-9 quai Saint Bernard, 75005 Paris

Vendredi 22 Mai 2026 11:30

Discovering brain circuits that change seasonally.
Giacomo Maddaloni | Institut de Psychiatrie et Neurosciences de Paris (IPNP)


Plus d'infos... Tags: Cognition, Neural circuit Annonce publiée le 11-04-2026

	NeuroPSI Salle de conference Albe-Fessard

Vendredi 22 Mai 2026 11:45

The emergence of the mouse pluripotent epiblast
Claire Chazaud


Invite par l'equipe Ribes / Nedelec, Claire Chazaud (DR INSERM, Institut GReD (CNRS/INSERM/Universite-Clermont-Auvergne) presentera un seminaire de l'Institut Jacques Monod sur le theme : The emergence of the mouse pluripotent epiblast Resume : Our project is to understand the genetic mechanisms of cell lineage differentiation in the mouse embryo during preimplantation. We are particularly interested in the specification between epiblast cells (Epi) and primitive endoderm cells (PrE) which takes place during the first 3 days in mice, corresponding to the first 6 days in humans.The Epi cells produce all the cells of the future individual and its descendants and are the source of the famouspluripotentES cells.Epi and PrE cells are specified from Inner Cell Mass (ICM) cells, and they express the transcription factors NANOG and GATA6, respectively, according to a salt and pepper pattern. How is this pattern is acquired has been the focus of our research, which highlights a combination of stochastic and deterministic mechanisms. Plus d'infos... Tags: Embryology, Developmental biology, Stem cells, Biotechnology, Inner cell mass, Epiblast, Homeobox protein NANOG, Cellular differentiation, Embryonic stem cell, Hypoblast, Epiblast-derived stem cell Annonce publiée le 23-04-2026

	Institut Jacques Monod Institut Jacques Monod Salle Francois Jacob, 15 rue Helene Brion, Paris, France

Vendredi 22 Mai 2026 14:00

Caracterisation genetique et moleculaire d'un cluster de trois snoRNAs impliques dans le metabolisme, la neurodegenerescence et la longevite chez la drosophile.
Theo Gauvrit | NeuroPSI - Unverite Paris-Saclay


Plus d'infos... Annonce publiée le 08-05-2026

	NeuroPSI Salle de conference Albe-Fessard

Mardi 26 Mai 2026 11:00

TBA
Helene de


TBA Plus d'infos... Tags: Helene, Draft:Toopy and Binoo: The Movie, Draft:Yellamma Annonce publiée le 31-03-2026

	Laboratoire Jean Perrin Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407

Mardi 26 Mai 2026 11:00

Seminar : Human mucosal and lymph nodeimmunobiology guiding development of herpesviral and HIV vaccines
Tony Cunningham


Professor Cunningham is an infectious diseases physician, clinical virologist, and internationally recognised researcher whose work has significantly advanced our understanding of HIV and herpesvirusimmunobiology, as well as contributed to vaccine development and clinical trials. ... Plus d'infos... Tags: Biology of bipolar disorder, Herpes, Lymph, HIV vaccine development Annonce publiée le 12-05-2026

	Institut Pasteur Salle Monod,

Mardi 26 Mai 2026 11:00

Kinetic Solubility as a Principle of Cellular Organization
Simon ALBERTI


Invite par: IBENS Functional Genomics Seminar Plus d'infos... Tags: Solutions, Cellular, Solubility, Kinetic Annonce publiée le 12-05-2026

	IBENS salle Amphithéâtre Galois, 45 rue d'Ulm 75005 Paris

Mardi 26 Mai 2026 11:00

How to build a molecular motor? Elucidating the molecular mechanism of assembly of the bacterial flagellum


Invite par: Nadia Izadi-Pruneyre Julien Bergeron Randall Centre for Cell and Molecular Biophysics, King's College London External attendees wishing to participate in the seminar are required to contact the following email addressdbsc@pasteur.frin order to obtain access to the ... Plus d'infos... Tags: Molecular machines, Biophysics, Molecular motor, Flagellum, Bacteria Annonce publiée le 20-02-2026

	Institut Pasteur Batiment Francois Jacob, salle Auditorium F. Jacob,

Mardi 26 Mai 2026 11:30

Innate control of neuronal activity and neuroinflammation by microglia
Dr Anne Schaefer | Max Planck Institute for Biology of Ageing


Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 23-03-2026

	College de France au College de France - Amphi Delmas-Marty - 11 place Marcelin Berthelot - 75005 Paris

Mercredi 27 Mai 2026 0:00

Thirteenth Symposium on Biology of Decision Making


Given the ongoing climate crisis, for this 2026 edition, we have decided to create a symposium maximising the possibility for invited speakers to travel by train or a short flight. We are nevertheless happy to host attendees from any place in the world. As we are aware of the tension between reducing carbon footprint and maintaining a diversity of countries, our model for SBDM may be reconsidered in next editions. The hope is to strike a right balance between sustainability and inclusivity across the years. Plus d'infos... Tags: Academic conference, Symposium Annonce publiée le 20-03-2026

	I. Cerveau et de la Moelle Mehdi Khamassi (CNRS / ISIR, Sorbonne Universite, Paris, France)

Mercredi 27 Mai 2026 11:30

Physical exclusion of heterochromatin at nuclear pores maintain global chromatin organization
Dr Charlene Boumendil | Igh


Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 15-12-2025

	College de France au College de France - Salle D2 - 11 place Marcelin Berthelot - 75005 Paris

Mercredi 27 Mai 2026 11:30

How do plant cell communicate ?
Emmanuelle BAYER


Our lab investigates how plasmodesmata (PD) regulate cell-to-cell communication in plants. These membrane-lined pores create cytoplasmic, plasma membrane (PM), and endoplasmic reticulum (ER) continuity between neighboring cells, allowing the direct exchange of proteins, RNAs, hormones, and metabolites. PD are central to the organization of plant multicellularity, yet their regulation remains poorly defined. We focus on the molecular mechanisms that shape PD specialization and function, with particular emphasis on their unique membrane architecture and its impact on intercellular trafficking. Using lipidomics, proteomics, super-resolution, electron tomography and expansion microscopy, molecular dynamics, and plant genetics, we address fundamental questions such as: What defines PD membrane domains? What role do lipids play in PD function? How do ER-PM contacts within PD control trafficking? Our work has revealed lipids as functional regulators of PD, uncovered the plasticity of their 3D structure, and demonstrated that PD act as specialized ER-PM membrane contact sites with dedicated tethering proteins. More recently, we showed that PD form through ER-dependent incomplete cytokinesis, redefining the role of the ER in establishing intercellular continuity. Together, these findings reshape our view of how plant cells connect and communicate. Plus d'infos... Tags: Organelles, Membrane biology, Plant anatomy, Cell biology, Cellular processes, Plasmodesma, Cytokinesis, Cell, Endoplasmic reticulum, Biological membrane, Lipidomics, Membrane contact site Annonce publiée le 17-04-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie

Jeudi 28 Mai 2026 9:00

Beckman-Coulter Workshop
Beckman-Coulter


Plus d'infos... Tags: Coulter, Surnames, Beckman, Draft:Beckman Coulter Life Sciences, Blood tests, Wallace H. Coulter Annonce publiée le 27-03-2026

	Centre de Recherche des Cordeliers

Vendredi 29 Mai 2026 11:45

SpatiotemporalEmergence of Somatosensory Neuron Diversity
Navajas Acedo


Invite par l'equipe Greenberg et l'equipe Konstantinides, Joaquin Navajas Acedo (Postdoc, Schier Lab at the University of Basel, Switzerland) presentera un seminaire de l'Institut Jacques Monod sur le theme : SpatiotemporalEmergence of Somatosensory Neuron Diversity Resume : My work uses a population of somatosensory neurons in the zebrafish spinal cord -the Rohon-Beard (RB) neurons- to address a fundamental question in neuroscience: How do cellular factors combine in space and time to generate robustly the diverse neuron types of a functional circuit?Live imaging and deep single-cell transcriptomics across development show that contrary to a ~150-year-old assumption, RB neurons do not disappear by programmed cell death and are heterogeneous at 3 levels: their transcriptome, their axial distribution, and inter-individual pattern. Combining in totocell lineage reconstruction and a custom whole-mount spatial transcriptomics -in the same animal- my work shows RB neurons possess extremely simple cell lineages and link them to dozens of transcription factors and somatosensory genes in space. Spatiotemporal analysis of RB subtype emergence reveals that it follows a staggered-layer logic, with a ?pan-RB program' preceding a stochastic ?hybrid neurotrophin receptor' state that resolves into mutually-exclusive subclasses, followed by specialized functional subtypes. I also define the regulatory mechanism by transcription factors underlying the seemingly stochastic, yet robust emergence of the observed neuronal subtypes across time. I also discuss this mechanism is likely conserved across Anamniotes. This work demonstrates that zebrafish RB neurons are an excellent model to study the precise molecular mechanisms underlying the development of neuron diversity at the single-cell level. Plus d'infos... Tags: Somatosensory system, Neurotrophin, Neuron, Computational neuroscience Annonce publiée le 23-04-2026

	Institut Jacques Monod Institut Jacques Monod Salle Francois Jacob, 15 rue Helene Brion, Paris, France

Lundi 01 Juin 2026 11:00

"Alzheimer'S Disease: Amyloid Biology and Fluid Biomarkers "
Mathias JUCKER | University of Tubingen Department Cell Biology of Neurological Diseases


The commonality of many neurodegenerative disorders is the progressive temporal and spatial aggregation of specific proteins in the brain. The quintessential proteopathy is Alzheimer's disease (AD), in which the aggregation and seeded propagation of amyloid peptide triggers AD pathogenesis, including neuronal Tau inclusions and neurodegeneration. Current therapeutic strategies focus on early disease stages and aim ta inactivate seed propagation before the onset of neurodegeneration. However, ta develop such primary prevention approaches a mechanistic understanding of early disease stages is essential. Plus d'infos... Tags: Alzheimer's disease, Amyloidosis, Biomarkers, Neurological disorders, Histopathology, Neurodegenerative disease, Amyloid beta, Amyloid, Tau protein, Mathias Jucker, Proteinopathy, Biochemistry of Alzheimer's disease Annonce publiée le 10-04-2026

	I. Cerveau et de la Moelle Institut du cerveau

Mardi 02 Juin 2026 0:00

22nd annual meeting of the Neural Network Development club


La journee scientifique annuelle du Club de Developpement des Reseaux Neuronaux a pour objectif de promouvoir les travaux des chercheurs de la communaute. Elle aura lieu le 2 juin 2026. Le programme est construit sur la base des resumes soumis pour communications orales. Les communications, en anglais, seront reparties en troissessions scientifiques , intercalees avec lesseminaires de conferenciers invites experts dans le domaine du neurodeveloppement. Les inscriptions pour la journee du club DRN sont ouvertesjusqu'au 19 mai 2026 via le site de l'evenement. L'inscription est obligatoire pour pouvoir participer aux conferences Le club Developpement des Reseaux Neuronaux a pour vocation de rassembler les chercheurs de differentes disciplines des neurosciences (developpement, physiologie, biochimie, pharmacologie?) interesses dans la construction des reseaux de neurones. Chaque annee, le club Developpement des Reseaux Neuronaux organise une journee scientifique dans le but de rassembler ces chercheurs, pour renforcer leurs interactions et mieux representer ce domaine de recherche au niveau des neurosciences francaises. Plus d'infos... Annonce publiée le 11-05-2026

	Institut Jacques Monod Institut Jacques Monod Amphitheatre Buffon, 15 rue Helene Brion, Paris, France

Mardi 02 Juin 2026 11:00

Chromatin architecture in Archaea - insights from cryo-EM and cryo-ET


Invite par: Ludovic Sauguet Dr. Svetlana Dodonova EMBL, Heidelberg, Germany External attendees wishing to participate in the seminar are required to contact the following email address dbsc@pasteur.fr in order to obtain access to the Institut Pasteur premises at least one week ... Plus d'infos... Tags: Cell biology, Cryogenic electron microscopy, Protein structure, Extremophiles, Archaea, Cryo Annonce publiée le 12-02-2026

	Institut Pasteur Batiment F. Jacob , salle F. Jacob Auditorium,

Mardi 02 Juin 2026 11:30

TBA
Dr Homaira Nawabi | Institut des Neurosciences, Grenoble


Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 23-03-2026

	College de France au College de France - Salle D2-11 place Marcelin Berthelot - 75005 Paris

Mardi 02 Juin 2026 14:00

Optique adaptative en microscopie de fluorescence a 2 photons pour la neuro-imagerie fonctionnelle chez la souris
Alice GUILLAUME-MANCA


Invite par: IBENS - Equipe Laurent BOURDIEU Plus d'infos... Annonce publiée le 05-05-2026

	IBENS salle Favard, IBENS 46 rue d'Ulm 75005 Paris

Mardi 02 Juin 2026 14:00

Advanced technologies for protein biomarker discovery
Aurelie Mouka


Invite par: Slobodan Culina Join us for the 2nd edition of an in-depth look at the newest technologies in the protein biomarker discovery field Plus d'infos... Tags: Biomarkers, Biomarker discovery, Cancer biomarker Annonce publiée le 08-05-2026

	Institut Pasteur Batiment: Metchnikoff building Salle: Salle Jules Bordet

Jeudi 04 Juin 2026 0:00

Air Pollution impact on the Resolution of Inflammation in Mucoviscidosis (cystic fibrosis) airway disease
Maëlys BORN-BONY (Institut Mondor de Recherche Biomédicale, Créteil)


Cystic fibrosis is a genetic disease characterized by a dehydration of airway mucus leading to increased viscosity, significant inflammation, lung infections and tissue damage. Because progression of the disease cannot be solely explained by genetic factors, some studies are now interested in the intrinsic and extrinsic factors that exacerbate CF symptoms. Among those factors, reduced levels of specialized proresolving lipid mediators (SPM) in CF airway and exposure to air pollution have been reported. In addition, some pollutants have been shown to impact SPM biosynthesis. However, the possible role of air pollution on SPM metabolism dysregulation in CF and the role of SPM in protecting CF airways from air pollution induced damages have not been explored. In our project, we use Scnn1b transgenic mice as a model for CF airway disease. In collaboration with the LISA (Interuniversity Laboratory of Atmospheric Systems / Laboratoire Interuniversitaire des Systèmes Atmosphériques), we study how exposure to a polluted atmosphere can impact the SPM and, more generally, the resolution of inflammation in the airway. Paris postdoc seminar series Plus d'infos... Tags: Lung disorders, Channelopathies, Cystic fibrosis, Fibrosis Annonce publiée le 18-12-2025

	Institut Cochin Salle Rosalind Franklin

Jeudi 04 Juin 2026 0:00

Imaging the Brain: New Probes & Approaches


On the occasion of the inauguration of the Paris Brain Institute as a new ZEISS Labs@location, we are pleased to invite you to a mini-symposium on the theme "Imaging the Brain: New Probes and Approaches". Plus d'infos... Tags: Neural engineering, Neuroimaging, Cognitive neuroscience Annonce publiée le 16-04-2026

	I. Cerveau et de la Moelle 09:00 - 09:15

Jeudi 04 Juin 2026 10:00

Revealing the Secrets of Ovulation
Christopher Thomas


Ovulation is essential for reproduction. During ovulation, an egg is released from an ovarian follicle into the oviduct. Once released, the egg can be fertilised by the sperm and give rise to a new embryo. Ovulation takes place inside the body, impeding studies of its progression. The exact mechanisms that control ovulation have therefore remained unclear. In this work, we devised methods to study the entire process of ovulation live in isolated ovarian follicles from mice using a long-term culture and imaging system. A combined approach of confocal and two-photon microscopy allowed for the study of ovarian processes at both the cellular and whole follicle scale. We show that ovulation proceeds through three distinct phases, follicle expansion (I), contraction (II), and rupture (III), culminating in the release of the egg. Follicle expansion is driven by the secretion of hyaluronic acid, and an osmotic gradient-directed influx of fluid into the follicle. Subsequently, smooth muscle cells in the outer follicle drive follicle contraction. Follicle rupture is initiated by the formation of a stigma in the thinnest region of the follicle wall, followed by the exit of follicular fluid and cumulus cells, and finally, the rapid release of the egg. Taken together, these results establish a mechanistic framework for ovulation, a process of fundamental importance to reproduction Plus d'infos... Tags: Menstrual cycle, Mammal female reproductive system, Midwifery, Human female reproductive system, Women's health, Ovulation, Ovarian follicle, Ovary, Stigma, Follicle, Cumulus oophorus, Ovarian follicle dominance Annonce publiée le 05-05-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e

Jeudi 04 Juin 2026 12:00

EXPANDing Immune Cells and their Tumor Antigens during Checkpoint Immunotherapy
Diether Lambrechts


Plus d'infos... Tags: Lambrechts, Diether, Charles Joseph Mathieu Lambrechts, Diether of Nassau Annonce publiée le 06-02-2026

	Centre de Recherche des Cordeliers

Jeudi 04 Juin 2026 14:30

How Geometry Drives Collective Cell Migration
Teck Lim


Invite par l'equipe Ladoux/Mege, Prof. Chwee Teck Lim ( Mechanobiology Institute, National University of Singapore ) presentera un seminaire de l'Institut Jacques Monod sur le theme : How Geometry Drives Collective Cell Migration Resume : Cells that migrate as sheets or large cohorts exhibit behaviors that differ markedly from those of individually migrating cells, particularly when subjected to geometric constraints, physical confinement, or out-of-plane topography. Collective cell migration underlies many essential biological processes, including wound healing, maintenance of the intestinal epithelium, embryonic development, and cancer invasion and metastasis. Understanding these collective behaviors therefore offers valuable insights into tissue repair mechanisms and the design of regenerative medicine strategies. Here, we investigate the kinematic properties of collectively migrating cell cohorts under a range of well-defined geometric and physical constraints, including migration along narrow strips and across out-of-plane curved surfaces, to elucidate how confinement and surface geometry shape collective cell dynamics. Bio : Professor Lim is the NUS Society Chair Professor and Director of the Institute for Health Innovation and Technology at NUS. He is also the Founding Director of the Singapore Health Technologies Consortium. His research interests include human disease mechanobiology and the development of microfluidic and wearable technologies for healthcare applications. He is a prolific researcher having co-authored over 500 journal publications and delivered more than 550 plenary/keynote/invited lectures. He is also a serial entrepreneur having started six companies with one public listed in 2018. Professor Lim is an Elected Fellow of the Royal Society (UK), Royal Academy of Engineering (UK), National Academy of Inventors (US), IUPESM, AIMBE, IAMBE, ASEAN Academy of Engineering and Technology, Academy of Engineering, Singapore, Singapore National Academy of Science and the Institution of Engineers. He and his team have garnered over 100 research awards and honours including the President's Science Award, Otto Schmitt Award, Nature Lifetime Achievement Award for Mentoring in Science, Asia's Most Influential Scientist, Highly Cited Researcher, IES Prestigious Engineering Achievement Award, ASEAN Outstanding Engineering Achievement Award, Asian Scientists 100, Credit Suisse Technopreneur of the Year Award, Wall Street Journal Asian Innovation Award (Gold), President's Technology Award, and the Distinguished Alumni Award among others. Plus d'infos... Tags: Education in Singapore, Cells, Collective cell migration, Oncology, National University of Singapore, Asian Scientist 100, Lim Chwee Teck Annonce publiée le 13-05-2026

	Institut Jacques Monod Institut Jacques Monod Salle Francois Jacob, 15 rue Helene Brion, Paris, France

Vendredi 05 Juin 2026 9:30

Grand challenges in vector-borne diseases


Invite par: Anna-Bella Failloux Grand challenges in vector-borne diseases Controlling vectors in the context of climate and environmental changes June 5th 2026 ? Institut Pasteur, Paris, France Registration is free but mandatory Registration form As part of the ... Plus d'infos... Tags: Infectious diseases, Epidemiology, Vector calculus, Disease transmission, Disease vector, Parasitology, Vector, Euclidean vector, Climate change and infectious diseases Annonce publiée le 07-11-2025

	Institut Pasteur Batiment: Duclaux Salle: Amphitheatre Duclaux

Vendredi 05 Juin 2026 11:45

Epigenetic regulation in development and disease
Alexander Meissner


Invite par l'Institut Jacques Monod et l'Unite Epigenetique et Destins Cellulaire, Alexander Meissner (Directeur, Max Planck Institute for Molecular Genetics) presentera une conference de l'Institut Jacques Monod sur le theme : Epigenetic regulation in development and disease Resume : In vertebrates, somatic cells stably maintain globally high DNA methylation levels and protect CpG island promoters, features that are extensively altered within mammalian extraembryonic tissues and the majority of human cancers.I will present recent insights from various models to explore the non-canonical regulation of DNA methylation Publications Ming-Kang Lee, Sebastian D. Mackowiak, Daniel Felismino, Jeron Venhuizen, Maria Walther, Alexander Meissner. Temporal degradation of PRC2 uncovers specific developmental dependencies. bioRxiv 2026.04.18.719361 Taguchi A, Magalhaes AP, Bolondi A, Lee MK, Kretzmer H, Wittler L, Hnisz D, Meissner A. Single-cell activation screen identifies hepatic maturation regulators with zonal resolution. Dev Cell. 2026 Mar 11;61(3):553-570.e9. Hetzel S, Hodis E, Torlai Triglia E, Kovacsovics A, Steinmann K, Gnirke A, Cui M, McQuaid D, Weigert R, Pohl G, Muzumdar MD, Leyvraz S, Keilholz U, Yaspo ML, Regev A, Kretzmer H, Smith ZD, Meissner A. Direct genetic transformation bypasses tumor-associated DNA methylation alterations. Genome Biol. 2025 Jul 17;26(1):212. Guckelberger P, Haut L, Tornisiello R, Kretzmer H, Meissner A. HELLS is required for maintaining proper DNA modification at human satellite repeats. Genome Biol. 2025 Jul 17;26(1):211. Batki J, Hetzel S, Schifferl D, Bolondi A, Walther M, Wittler L, Grosswendt S, Herrmann BG, Meissner A. Extraembryonic gut endoderm cells undergo programmed cell death during development. Nat Cell Biol. 2024 Jun;26(6):868-877. Sampath Kumar A, Tian L, Bolondi A, Hernandez AA, Stickels R, Kretzmer H, Murray E, Wittler L, Walther M, Barakat G, Haut L, Elkabetz Y, Macosko EZ, Guignard L, Chen F, Meissner A. Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis. Nat Genet. 2023 Juf?5(7):1176-1185. Weigert R, Hetzel S, Bailly N, Haggerty C, Ilik IA, Yung PYK, Navarro C, Bolondi A, Kumar AS, Anania C, Brandl B, Meierhofer D, Lupianez DG, Muller FJ, Aktas T, Elsasser SJ, Kretzmer H, Smith ZD, Meissner A. Dynamic antagonism between key repressive pathways maintains the placental epigenome. Nat Cell Biol. 2023 Apr;25(4):579-591. Hetzel S, Mattei AL, Kretzmer H, Qu C, Chen X, Fan Y, Wu G, Roberts KG, Luger S, Litzow M, Rowe J, Paietta E, Stock W, Mardis ER, Wilson RK, Downing JR, Mullighan CG, Meissner A. Acute lymphoblastic leukemia displays a distinct highly methylated genome. Nat Cancer. 2022 Jun;3(6):768-782. doi: 10.1038/s43018-022-00370-5. Plus d'infos... Tags: Epigenetics, Post-translational modification, DNA, Gene expression, Methylation, DNA methylation, Regulation of gene expression, Epigenome, Transcription, Alexander Meissner, Max Planck Institute for Molecular Genetics Annonce publiée le 14-05-2026

	Institut Jacques Monod Institut Jacques Monod Amphitheatre Buffon, 15 rue Helene Brion, Paris, France

Vendredi 05 Juin 2026 17:00

Why neuroscientists love the Head Direction system
Desdemona Fricker | SPPIN, Universite Paris Cite


Plus d'infos... Tags: Fricker, Desdemona Annonce publiée le 19-08-2025

	Neural Networking Night pub Le Piano Vache - 8 Rue Laplace, 75005 Paris

Lundi 08 Juin 2026 0:00

Cancers gynecologiques : de la pratique clinique a la biologie


Ce cours avance de trois jours offre un apercu complet des derniers developpements en matiere de pratique clinique, de recherche et d innovation therapeutique. Les participants exploreront les donnees scientifiques de pointe, les technologies emergentes, et les defis lies aux soins gynecologiques. Concu pour les professionnels experimentes, le programme met l accent sur des connaissances approfondies et des perspectives d avenir dans les cancers gynecologiques. Plus d'infos... Annonce publiée le 04-03-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e

Lundi 08 Juin 2026 9:00

From AMR to Emerging Threats: Understanding Pathogens for Effective Control


Invite par: Aude Bernheim A Joint Symposium by Labex IBEID et Pasteur 2030 Priority 1 The program will be uploaded soon. Plus d'infos... Tags: Infectious diseases, Microbiology, Pathogen, Zoonoses, Evolutionary biology Annonce publiée le 20-02-2026

	Institut Pasteur Batiment: Amphitheatre Duclaux

Lundi 08 Juin 2026 11:00

Scientific lectures: May The Force Be With You! Piezo Channels in Mechanosensory Biology
Ardem Patapoutian | Department of Neuroscience, Scripps Research - Presidential Endowed Chair


Mechanotransduction was perhaps the last major sensory modality not understood at the molecular level. Proteins/ion channels that sense mechanical force are postulated to play critical roles in sensing touch/pain (somatosensation), sound (hearing), shear stress (cardiovascular function), etc.; however, the identity of ion channels involved in sensing mechanical force had remained elusive. The Patapoutian lab identified PIEZO1 and PIEZO2, mechanically activated cation channels that are expressed in many mechanosensitive cell types. Genetic studies established that PIEZO2 is the principal mechanical transducer for touch, proprioception, baroreception, bladder, and lung stretch, and that PIEZO1 mediates blood-flow sensing, which impacts vascular development and iron homeostasis. Clinical investigations have confirmed the importance of these channels in human physiology. Current work in Patapoutian continues to explore the role of mechanosensation and interoception in physiology and disease. Plus d'infos... Tags: Transmembrane proteins, Sensory systems, PIEZO2, Ardem Patapoutian, PIEZO1, Piezo, Mechanosensation, Mechanotransduction, Proprioception, Sense, Somatosensory system, Ion channel Annonce publiée le 07-04-2026

	I. Cerveau et de la Moelle Institut du cerveau

Mardi 09 Juin 2026 11:30

"CANCELLED"
Dr Laurent Seugnet


Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 06-01-2026

	College de France au College de France - Salle D2 - 11 place Marcelin Berthelot - 75005 Paris

Mardi 09 Juin 2026 11:30

TBA
Dr Annika Keller | University Hospital Zurich


Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 29-04-2026

	College de France au College de France - Salle a venir -11 place Marcelin Berthelot - 75005 Paris

Jeudi 11 Juin 2026 11:00

Staphylococcus epidermidis DnaK alters biofilm formation and proteome in S. aureus CIP 107093
Yoan Konto-Ghiorghi


Invite par: Philippe Gaudu Staphylococcusaureus and Staphylococcusepidermidis, two Gram-positive members of the skin microbiota, form biofilms involved in dysbiosis and inflammatory skin diseases. We investigated the role of the molecular chaperone DnaK from S.epidermidis in biofilm formation. Recombinant DnaK modulates biofilm formation in a strain-dependent manner: it increases biofilm biomass in commensal strains but significantly reduces it in the clinical S.aureus strain CIP107093. Using point mutants of DnaK, we show that the substrate-binding domain is required for this inhibitory effect. Proteomic analysis indicates that recombinant DnaK, added extracellularly, alters the biofilm proteome of S.aureus, affecting protein degradation systems and biofilm regulators, thus revealing a cross-species regulatory role within the skin microbiota. Plus d'infos... Tags: Gram-positive bacteria, Pathogenic bacteria, Bacteriology, Environmental microbiology, Human microbiome, Staphylococcus epidermidis, Staphylococcus aureus, Biofilm, Hsp70, Skin flora, Staphylococcus Annonce publiée le 18-03-2026

	Institut Micalis Auditorium 442 - Institut Micalis

Vendredi 12 Juin 2026 11:30

Neurobiological mechanisms of social behaviour.
Camilla Bellone


Invite par: BOUVIER Guy Plus d'infos... Annonce publiée le 21-04-2026

	NeuroPSI Salle de conference Albe-Fessard

Lundi 15 Juin 2026 11:00

"Equivalent learning emerges from distinct population dynamics across brain networks"
Flavio DONATO | University of Basel - Biozentrum the center for molecular life sciences


Learning requires identifying population activity patterns associated with desired outcomes and acquiring the ability to volitionally recruit them. Whether such processes rely on shared or circuit-specific population dynamics across the brain remains unresolved. A fundamental challenge is that different brain regions typically underpin distinct behaviors, making it difficult to disentangle circuit-specific learning mechanisms from region-specific behavioral demands. Here, we overcome this limitation using a brain-computer interface (BCI) to impose an identical, population-defined learning problem across brain networks. By making reward contingent directly on neuronal population activity, we apply the same associative learning paradigm under identical conditions to two regions with prominent recurrent connectivity but fundamentally distinct dynamical regimes: primary motor cortex (M1) and hippocampal area CA3. Mice acquired robust volitional control in both regions, demonstrating that distinct circuits can support equivalent goal-directed learning. In both M1 and CA3, learning drove progressive sparsification of population activity and greater population-level representation of the reward state. The underlying population dynamics, however, diverged. M1 showed sustained pre-reward excitation and population trajectories that flowed continuously through the reward state, with manifold geometry separating behavioral states. CA3 exhibited a learning-dependent temporal reversal, shifting from pre-reward excitation to post-reward inhibition, with population trajectories converging onto the reward state before rapidly resetting to baseline, and distinct behavioral states collapsing onto a shared manifold subspace. Recurrent network models with distinct connectivity architectures and dynamical constraints, matched to each region, recapitulated these population-level dynamics, linking intrinsic circuit structure to the geometry of learned activity. These findings demonstrate that equivalent learning outcomes can arise from fundamentally different population-level implementations, reflecting intrinsic circuit constraints rather than conserved population-level strategies. This principled degeneracy indicates that learning emerges not from a single canonical solution, but from multiple circuit-specific implementations shaped by local dynamics. Plus d'infos... Tags: Hippocampus, Limbic system, Reward system, Brain, Network neuroscience Annonce publiée le 10-04-2026

	I. Cerveau et de la Moelle Institut du cerveau

Mardi 16 Juin 2026 9:00

4th nICE Day symposium of Cryo-EM users


Invite par: Francesca Gubellini The Structural Biology and Chemistry Department together with the Center for Technological Resources and Research C2RT will run the nICE-Day? event on June 16th from 9am to 6pm in the Duclaux lecture hall. This ... Plus d'infos... Tags: Protein structure, Cell biology, Cryogenic electron microscopy, Structural biology, Fellows of the Royal Society Annonce publiée le 07-05-2026

	Institut Pasteur Salle Amphi Duclaux,

Mardi 16 Juin 2026 11:00

TBA
| LJP


TBA Plus d'infos... Tags: LJP, National Youth Council of Latvia, Liberty and Justice Party Annonce publiée le 11-12-2023

	Laboratoire Jean Perrin Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407

Mardi 16 Juin 2026 11:30

TBA
Dr Guy Bouvier | NeuroPSI


Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 29-04-2026

	College de France au College de France - Salle a venir -11 place Marcelin Berthelot - 75005 Paris

Mercredi 17 Juin 2026 14:00

Integration somatosensori-motrice corticale lors de l'apprentissage moteur, etudiee a l'aide d'une interface cerveau-machine en boucle fermee.
Alexandre Tolboom | NeuroPSI - Unverite Paris-Saclay


Plus d'infos... Annonce publiée le 14-05-2026

	NeuroPSI Salle de conference Albe-Fessard

Jeudi 18 Juin 2026 9:00

Artificial Intelligence in Biology et Health


Invite par: Laurent Essioux The Institut Pasteur is organizing its 3rd edition of its SymposiumArtificial Intelligence in Biology and Health. It will be held on 4thOctober 2024 in the Emile Duclaux lecture hall at the Institut Pasteur campus. ... Plus d'infos... Tags: COVID-19 pandemic in France, Pasteur Institute, mile Duclaux, Louis Pasteur Annonce publiée le 14-02-2026

	Institut Pasteur Batiment: Duclaux Salle: Duclaux lecture hall

Jeudi 18 Juin 2026 11:00

Surface-based cell-free platform to characterize host-pathogen interactions
Aurore Dupin


Invite par: Joshua Ricouvier The immune system is one of the most complex systems of the human body. At its core, it uses protein-protein interactions to achieve the emergent property of differentiating self from other. Synthetic biology aims to implement biological functions of natural living systems, to test hypothesis and to expand them beyond their current limits. Here, we mimic key protein-protein interactions and functions of the immune system using a cell-free surface-based approach. We use innovative silicon chips to parallelize antigen display and antibody epitope screening. Linear DNA sequences are immobilized in micrometer-sized carved compartments. Phenotype and genotype are linked in every compartment by localized on-chip expression and capture of antigens. Binding to a panel of viral antigens is assessed with high specificity for monoclonal antibodies and for polyclonal antibodies in human serum, revealing a rich picture of epitopes and individual immune profiles. This platform mimics and extends the function of antigen-presenting cells, allowing us to interrogate protein-protein interaction between host receptor, pathogenic antigen and immune system. Plus d'infos... Tags: Immune system, Immunology, Epitope, Polyclonal antibodies, Antigen, Antibody, Monoclonal antibody, Immune receptor, Polyclonal B cell response, Immunomics Annonce publiée le 07-04-2026

	Institut Micalis Auditorium 442 - Institut Micalis

Jeudi 18 Juin 2026 12:30

From the M1/M2 paradigm, to spatial determinism of tumor-associated macrophageheterogeneity
Alexandre Boissonnas


This presentation proposes that TAM heterogeneity and functions are determined by their origin and localization in distinct tumor sub-anatomic niches and challenges the association with the M1/M2 binary model.BOISSONNAS Alexandre, Principal Investigator- (Directeur de recherche Inserm) Team leader Spatio-temporal organization and regulation of myeloid cells STORM. Institut Mondor de Recherche Biomedicale IMRB U955, Universite Paris-Est Creteil.Alexandre Boissonnas is an immunologist and Research Director at the French National Institute of Health and Medical Research (Inserm). He obtained his PhD in 2004, during which he investigated the role of antigen in the homeostasis of peripheral T lymphocytes. He then joined Sebastien Amigorena In 2009, he was recruited by Inserm at CIMI-Paris where he established and has since led his own research team focusing on monocyte and macrophage biology. He recently moved to IMRB in Creteil, continuing his investigations on the dynamics of the mononuclear phagocyte system in inflammatory diseases and cancer. His laboratory combines high-dimensional immunomonitoring with advanced imaging technologies to unravel the spatio-temporal organization and regulation of the macrophage compartment, as well as its responses to tissue injury and neoplastic transformation. Plus d'infos... Tags: Macrophages, Immune system, Oncology, Tumor-associated macrophage, Macrophage Annonce publiée le 09-04-2026

	Centre de Recherche des Cordeliers

Vendredi 19 Juin 2026 11:00

Adaptive immunity to the commensal microbiota
Ivanov Ivaylo


1. Gelsinger DR ... Ivanov II#, Sternberg SH#, Wang HH#. Metagenomic editing of commensal bacteria in vivo using CRISPR-associated transposases. Science 2025. #co-corresponding author 2. Araujo LP ... Ivanov II. Context-dependent role of group 3 innate lymphoid cells in mucosal protection. Science Immunology 2024. 3. Brockmann L ... Ivanov II. Intestinal microbiota-specific Th17 cells possess regulatory properties and suppress effector T cells via c-MAF and IL-10. Immunity 2023. 4. Kawano Y ... Ivanov II. Dietary sugar-induced microbiota imbalance disrupts immune-mediated protection from metabolic syndrome. Cell 2022. 5. Ladinsky MS ... Bjorkman PJ#, Ivanov II#. Endocytosis of commensal antigens by intestinal epithelial cells regulates mucosal T cell homeostasis. Science 2019. #co-corresponding author 1. Gelsinger DR ... Ivanov II#, Sternberg SH#, Wang HH#. Metagenomic editing of commensal bacteria in vivo using CRISPR-associated transposases. Science 2025. #co-corresponding author 2. Araujo LP ... Ivanov II. Context-dependent role of group 3 innate lymphoid cells in mucosal protection. Science Immunology 2024. 3. Brockmann L ... Ivanov II. Intestinal microbiota-specific Th17 cells possess regulatory properties and suppress effector T cells via c-MAF and IL-10. Immunity 2023. 4. Kawano Y ... Ivanov II. Dietary sugar-induced microbiota imbalance disrupts immune-mediated protection from metabolic syndrome. Cell 2022. 5. Ladinsky MS ... Bjorkman PJ#, Ivanov II#. Endocytosis of commensal antigens by intestinal epithelial cells regulates mucosal T cell homeostasis. Science 2019. #co-corresponding author Plus d'infos... Tags: Immune system, Bacteriology, Microbiomes, T cells, Microbiology, Intestinal epithelium, T helper 17 cell, Microbiota, Human microbiome, Gut microbiota, Innate lymphoid cell, Gut-associated lymphoid tissue Annonce publiée le 06-05-2026

	Institut Curie Centre de recherche - Orsay - Amphitheatre du Batiment 111

Lundi 22 Juin 2026 11:00

"The hippocampal latent diffusion engine: a computational framework for memory, perception, and cognitive dysfunction"
Michael BREAKSPEAR | University of New Castle school of Science.


The hippocampus is a cognitive hub whose functions are disrupted in most major neurodegenerative dementias. Drawing on recent advances in generative artificial intelligence and systems neuroscience, we conceptualize the hippocampus as a latent diffusion engine that compresses sensory, internal, and cognitive inputs into low-dimensional representations and then regenerates percepts, episodic memories, and imagined scenes for cortical integration. Travelling waves of cortico-hippocampal oscillations, aligned with large-scale functional gradients, schedule and structure this generative process, organizing distributed neural activity into coherent, semantically grounded constructs. We also demonstrate how major neurodegenerative dementias - including the Alzheimer&'s disease spectrum - can be interpreted as selective breakdowns of the anatomical and computational components of this proposed architecture. Plus d'infos... Tags: Cognitive disorders, Aging-associated diseases, Learning disabilities, Limbic system, Dementia, Hippocampus, Alzheimer's disease Annonce publiée le 07-04-2026

	I. Cerveau et de la Moelle Institut du cerveau

Mardi 23 Juin 2026 9:00

Stroma immunite et cancer


Cette journee sera consacree aux recherches fondamentales et appliquees dans le domaine en pleine expansion des interactions entre cellules stromales (en particulier les fibroblastes et les cellules endotheliales) et cellules immunitaires au sein du microenvironnement tumoral (TME). Au cours de la derniere decennie, le stroma tumoral est devenu une cible therapeutique prometteuse dans le cancer, les fibroblastes associes au cancer (CAF) jouant un role cle dans la structuration du TME, la regulation de la croissance tumorale, l'evasion immunitaire et la resistance aux chimiotherapies et immunotherapies. Le nombre d'experts en France travaillant dans ce domaine ne cesse de croitre, et nous ressentons le besoin d'organiser un symposium qui reunisse des chercheurs experimentes et des debutants afin de favoriser la creation d'une communaute. Inspire par les initiatives fructueuses des dernieres decennies autour de la recherche sur les lymphocytes et les cellules myeloides, ce symposium vise a aider un cercle pluridisciplinaire d'experts interesses par les fibroblastes du TME a etablir des consensus sur les pratiques experimentales, proposer des nomenclatures unifiees, partager des resultats et echanger des modeles. L'objectif de ce symposium est de renforcer les collaborations naissantes et d'accroitre la visibilite internationale de l'Institut Curie et de la France dans le domaine de l'etude du stroma dans le cancer. Il s'adresse a des personnes disposant d'au moins des connaissances de base en biologie ou immunologie (niveau recommande : Master). Cet evenement sera egalement une opportunite pour faire progresser la recherche translationnelle et le developpement de traitements anticancereux ciblant specifiquement les composants stromaux. Le symposium se tiendra le mardi 23 juin 2026, de 8h30 a 20h, dans l'Amphitheatre Constant Burg (12 rue Lhomond, 75005 Paris, niveau -1), le plus spacieux et confortable de l'Institut Curie, avec ses 196 places. Nous esperons accueillir entre 120 et 150 participants. Les scientifiques que nous avons invites et qui ont confirme leur participation pour presenter leurs projets et leurs resultats les plus recents dans le domaine du stroma, de l'immunite et du cancer, sont listes ci-dessous par ordre alphabetique : CONFERENCIERS PRINCIPAUX (KEYNOTE SPEAKERS) Alexandra Naba - Etats-Unis Shannon Turley - Etats-Unis INTERVENANTS (SPEAKERS) Corinne Bousquet - France Cedric Gaggioli - France Fatima Mechta-Grigoriou - France Lucie Peduto - France Helene Salmon - France Karine Tarte - France Danijela Vignjevic - France En complement, trois jeunes postdocs/chercheurs (1 venant de l'UE, 1 hors Paris et 1 parisien) seront selectionnes pour des presentations courtes (10 minutes + 5 minutes de questions). La selection se fera sur la base des resumes des posters soumis lors de l'inscription. Nous veillerons autant que possible a respecter la parite hommes-femmes parmi les intervenants. L'inscription au symposium sera gratuite mais obligatoire. Nous diffuserons largement l'annonce afin de maximiser la visibilite et d'attirer des chercheurs, etudiants, medecins et ingenieurs internationaux, qui devront prendre en charge leurs frais de voyage et d'hebergement. Une session de posters accompagnee d'un « vin et fromage » sera organisee en fin de symposium, mais les posters pourront etre affiches des le matin a proximite de l'espace cafe/dejeuner pour favoriser les echanges tout au long des pauses. L'IHU Cancers de femmes de l'Institut Curie sponsorise cet evenement, dont la thematique correspond a l'un de ses axes de recherche. Plus d'infos... Annonce publiée le 08-11-2025

	Institut Curie Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e

Mardi 23 Juin 2026 9:00

Colloque : Stroma immunite et cancer


Cet evenement d'une journee sera consacre a la recherche fondamentale et appliquee dans le domaine en pleine expansion des interactions entre cellules stromales (notamment fibroblastes et cellules endotheliales) et cellules immunitaires au sein du microenvironnement tumoral (TME). Au cours de la derniere decennie, le stroma tumoral est apparu comme une cible therapeutique prometteuse dans le cancer, les fibroblastes associes au cancer (CAF) jouant un role cle dans la structuration du TME, la regulation de la croissance tumorale, la promotion de l'evasion immunitaire et la contribution a la resistance auxchimiotherapie et auximmunotherapies. Les scientifiques que nous avons invites et qui ont confirme leur participation pour presenter leurs projets et leurs resultats les plus recents dans le domaine du stroma, de l'immunite et du cancer sont listes ci-dessous par ordre alphabetique : CONFERENCIERS INVITES (KEYNOTE) Alexandra Naba - USA Shannon Turley - USA INTERVENANTS Corinne Bousquet - France Cedric Gaggioli - France Fatima Mechta-Grigoriou - France Lucie Peduto - France Helene Salmon - France Karine Tarte - France Danijela Vignjevic - France En plus de ces intervenants, trois jeunes post-doctorants/chercheurs (1 de l'UE, 1 hors Paris et 1 de Paris) seront selectionnes pour des presentations courtes (10 minutes + 5 minutes de questions). La selection se fera sur la base des resumes de posters soumis lors de l'inscription. Nous veillerons a assurer un equilibre hommes-femmes parmi les intervenants. L'inscription au symposium sera gratuite mais obligatoire. Nous diffuserons largement l'annonce du symposium afin de maximiser sa visibilite et d'attirer des chercheurs, etudiants, medecins et ingenieurs internationaux, qui prendront en charge leurs frais de deplacement et d'hebergement. Une session poster accompagnee de vin et fromage se tiendra a la fin du symposium, mais les posters seront affiches des le matin pres de la zone cafe/dejeuner pour encourager les echanges tout au long des pauses. L'IHU Cancers des Femmes de l'Institut Curie sponsorise l'evenement, car le theme s'inscrit dans l'une de ses priorites de recherche. Inscription gratuite mais obligatoire avant le 10 juin 2026:https://forms.office.com/e/pMdqmCLZcP Plus d'infos... Annonce publiée le 14-11-2025

	Institut Curie Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e

Mardi 23 Juin 2026 11:30

Immunity in context: how tissues instruct immune responses


Invite par: Pierre Guermonprez Laura Mackay Peter Doherty Institute for Infection and Immunity, Australia ABSTRACT Immune responses are often inferred from blood, yet many T cells reside long-term within tissues, where local context shapes their behaviour. Tissue-resident memory ... Plus d'infos... Tags: Immune system, Immunology, Laura Mackay, T cell, Nonspecific immune cell, Mucosal immunology Annonce publiée le 23-04-2026

	Institut Pasteur Salle AGNES ULLMAN AUDITORIUM ,

Mardi 23 Juin 2026 12:30

Title to come
Miriam Merad


Plus d'infos... Tags: Merad, Miriam, The President Annonce publiée le 10-04-2026

	Centre de Recherche des Cordeliers

Mercredi 24 Juin 2026 16:30

Titre à venir
Clement Carre/Laure Teysset's Lab and Reini Luco


TBC soon - stay tuned! Plus d'infos... Tags: Reini, Luco, Stay Tuned, Laure Annonce publiée le 16-03-2026

	Paris RNA Club Auditorium Gallois - 45 rue d Ulm, 75005 Paris

Jeudi 25 Juin 2026 10:00

Adjusting the timing of mammalian development.
Aydan Karslioglu


Pluripotency provides the foundation of embryonic development and regenerative medicine. Pluripotency is also remarkably dynamic, as it can alternate between different states and can be promptly resolved to allow lineage specification. As such, e mbryonic development relies on stem cell function in balance with differentiation. We investigate how this balance is maintained in coordination with the environment and the protective measures the embryos take at times of scarcity. Our mission is to decode the process of dormancy and identify the genetic, epigenetic, and metabolic mechanisms that govern this fascinating phenomenon. Plus d'infos... Tags: Developmental biology, Biotechnology, Cell biology, Stem cells, Cloning, Cellular differentiation, Cell potency, Adult stem cell Annonce publiée le 09-04-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e

Jeudi 25 Juin 2026 12:00

The many faces of doxorubicin and how to improve it for new cancer therapies
Sjaak Neefjes


Anthracyclines like doxorubicin are still cornerstones in the treatment of a series of tumors. They should act by poisoning topoisomerase II causing DNA double stranded breaks. However, they also evict histones at defined sites in chromatin. We chemically separated these two activities to show that histone eviction was the most cytotoxic activity. Doxorubicin variants acting through histone eviction are active cancer drugs but have lost various toxic side effects including dose-dependent cardiotoxicity. These variants can still be used in the treatment of relapsed cancer patients and can strongly improve their overall survival. New activities in old cancer drugs can thus be explored to control toxicities, allow chronic treatment and improve the quality of life of cancer survivors. Plus d'infos... Tags: Anthracyclines, Antineoplastic drugs, Doxorubicin, Teratogens, Anthracycline, Chemotherapy, Cardiotoxicity, Histone, CytRx, Zoptarelin doxorubicin Annonce publiée le 24-04-2026

	Centre de Recherche des Cordeliers

Vendredi 26 Juin 2026 10:00

Mechanoregulation of Cytotoxic Lymphocyte Function
Morgan Huse


I trained as a structuralbiologist/peptide chemist, with John Kuriyan and Tom Muir at Rockefeller University, before carrying out postdoctoral research with Mark Davis and Stanford. There, I became interested in the structure and function of immune cell-cell interactions. I joined the Immunology Program at Memorial Sloan Kettering Cancer Center in 2007. My lab has primarily focused on the cytotoxic immune synapse, which is the specialized junction used by cytotoxic lymphocytes to destroy infected or transformed target cells. Over the past decade, we have become particularly interested in the mechanobiology of this interface, in particular how physical forces and mechanical properties shape its potency and specificity. My talk will address the role of lymphocyte mechanosensing in anti-tumor immune responses. Plus d'infos... Tags: Immune system, Lymphocyte, Immunological synapse, T cell Annonce publiée le 08-05-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e

Lundi 29 Juin 2026 11:00

"Neuromodulation of Brain States"
Luis DELECEA | Depart of Psychiatry & Behavorial Sciences Stanford University School of Medicine


The arousal construct underlies a spectrum of behaviors that include sleep, exploration, feeding, sexual activity and adaptive stress. Pathological arousal conditions include stress, anxiety disorders, and addiction. In the past few years we have used optogenetics to interrogate neuronal circuits underlying transitions between arousal states. In particular, I will talk about two new circuits identified in our laboratory: one predicts the onset and duration of REM sleep with unprecedented precision; another induces sleep in response to inflammatory cytokines. I will also present a novel method that displays cortex-wide fluctuations in membrane voltage using TEMPO imaging. Finally, I will discuss noninvasive neuromodulation methods for sleep intervention. Plus d'infos... Tags: Neurophysiology, Neuromodulation, Rapid eye movement sleep, Brain Annonce publiée le 08-04-2026

	I. Cerveau et de la Moelle Institut du cerveau

Mardi 30 Juin 2026 9:30

Single-molecule mechanics of eukaryotic and bacterial SMC complexes
Maxim Molodtsov


Structural Maintenance of Chromosomes (SMC) complexes are conserved molecular machines that help organize genomes in organisms ranging from bacteria to humans. They perform two essential tasks: they establish DNA-DNA interactions and extrude DNA loops, thereby shaping chromosome architecture and supporting faithful chromosome segregation. In this talk, I will discuss recent single-molecule studies from our group that reveal how these machines work under force. Using optical tweezers combined with fluorescence microscopy, we directly measure how strongly individual SMC complexes interact with DNA while visualizing their activity. We find that cohesin and condensin can form highly stable DNA connections capable of resisting the forces generated during cell division. By contrast, cohesin-mediated loop extrusion depends on much weaker and more dynamic DNA interactions, allowing loops to be readily remodelled. Comparisons with bacterial SMC complexes show that these machines can be stronger and more efficient loop extruders than their eukaryotic counterparts. Together, these findings suggest that SMC complexes have evolved different mechanical properties to match their specific roles in chromosome folding, maintenance, and segregation. Plus d'infos... Tags: Mitosis, Cell cycle, Nuclear organization, Condensin, Cohesin, Loop extrusion, SMC protein, Chromosome, DNA, Chromosome condensation Annonce publiée le 08-05-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie

Mardi 30 Juin 2026 11:30

TBA
Dr Nicolas Renier | ICM


Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 29-04-2026

	College de France au College de France - Salle a venir -11 place Marcelin Berthelot - 75005 Paris

Jeudi 02 Juillet 2026 9:00

The 11th edition of Start-me up on July 2 et 3, 2026


Invite par: Jong Eun Ihm Start-meup? is an annual two-day event that explores the latest trends in the life sciencesand health innovation ecosystem while guiding participants through the startup creation journey. This year’s expert talks session focuses on how ... Plus d'infos... Tags: Entrepreneurship, Business incubators, Private equity, Startup company, Innovation Annonce publiée le 04-03-2026

	Institut Pasteur Batiment: Centre Francois Jacob Salle: Auditorium

Jeudi 02 Juillet 2026 12:00

Title to come
Kevin Boye


Plus d'infos... Tags: Boye, Hans Boye, Come, Thou Fount of Every Blessing Annonce publiée le 29-04-2026

	Centre de Recherche des Cordeliers

Lundi 06 Juillet 2026 11:30

TBA
Dr Jun Nagai | Riken Center for brain science


Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 29-04-2026

	College de France au College de France Salle D2 - 11 place Marcelin Berthelot - 75005 Paris

Mardi 07 Juillet 2026 11:00

Harnessing Viral Mimicry in Cancer Vaccines
Nicolas VABRET


Despite advances in mRNA-based cancer vaccines, therapeutic responses remain limited by poorly immunogenic tumors that fail to support effective T cell infiltration, expansion, and function. Epigenetic therapies can enhance tumor immunogenicity by reactivating transposable elements (TEs), triggering innate sensing of immunogenic nucleic acids through a process known asviral mimicry.In this seminar, I will discuss how the DNA methyltransferase inhibitors induces viral mimicry in preclinicaltumourmodels, leading to type I interferon responses, enhanced antigen presentation, and remodeling of the immunosuppressive tumor microenvironment. This response depends on cancer-intrinsic nucleic acid sensors and supports the expansion and function of vaccine antigen-specific T cells within tumors.Together, these findings identify viral mimicry as a strategy to license therapeutic cancer vaccination and improve anti-tumor immunity. Plus d'infos... Tags: Immunology, Oncology, Immune system, Biotechnology, Immunogenicity, Cancer vaccine, Antigen, Tumor microenvironment, Glioma 261, Cancer immunotherapy Annonce publiée le 06-05-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e

Mercredi 08 Juillet 2026 11:30

Gliding Motion of Diatoms: Motors, Filaments, and Dynamic Trajectory Control
Stefan Diez


Raphid diatoms exhibit rapid gliding motility with remarkable directional flexibility, yet the underlying mechanisms remain poorly understood. Using Craspedostauros australis as a model, we combine phylogenomics, live-cell imaging, and high-resolution microscopy to dissect both force generation and trajectory control. We find that raphe-associated actin bundles do not show directional turnover, arguing against a direct role of actin dynamics in force production. Instead, we identify diatom-specific myosins (CaMyoB-D) that display coordinated movement during gliding, consistent with a motor function. At the cellular level, diatoms dynamically modulate their trajectories by switching between one- and two-raphe contact with the substrate. This switching controls path curvature, with single-raphe gliding producing curved paths and dual-raphe gliding resulting in straighter motion. Together, our results suggest a mechanism in which myosin-driven force generation is coupled to dynamic regulation of cell-substrate contact, enabling flexible navigation in complex environments. Plus d'infos... Tags: Protein families, Actin, Autoantigens, Myosin, Diatom, Gliding motility Annonce publiée le 24-04-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie

Lundi 14 Septembre 2026 14:00

EMBO Workshop The complexity of mycobacterial infections: From research to real-world impact


Invite par: Giulia Manina Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains one of the deadliest infectious diseases worldwide. Meanwhile, non-tuberculous mycobacteria (NTM) are an increasing global health concern. NTM infections often resemble TB clinically, which can lead to ... Plus d'infos... Tags: Acid-fast bacilli, Bacterial diseases, Tuberculosis, Pathogenic bacteria, Infectious causes of cancer, Nontuberculous mycobacteria, Mycobacterium, Mycobacterium fortuitum, Mycobacterial cervical lymphadenitis Annonce publiée le 26-02-2026

	Institut Pasteur Batiment CIS, salle ,

Lundi 21 Septembre 2026 0:00

Conference Jacques Monod - The mechanistic and evolutionary basis of programmed DNA elimination


The Conference Jacques Monod » The mechanistic and evolutionary basis of programmed DNA elimination» will take place fromMonday, September 21, 2026 toFriday, September 25, 2026 in Roscoff (Bretagne, France). Abstracts submission deadline :Tuesday, May 5, 2026 Deadline for payment of registration fees :July 2, 2026 Deadline for return of completed forms :July 2, 2026 Registration and abstract submission website Beyond mutations, the genetic content of an organism is generally constant across cells throughout development. Programmed DNA elimination (PDE) - a process in which specific cell lineages lose DNA segments or whole chromosomes - represents is a striking deviation to this principle. PDE is widespread in eukaryotes and plays roles in a variety of cellular processes, including gene silencing, germline differentiation, genome defence, and non-Mendelian inheritance. It manifests in diverse biological contexts, including the formation of germline-limited genomes, meiotic elimination of parental chromosomes, and sex determination via X-chromosome loss. In recent years, it has become increasingly clear that PDE occurs across a wide range of phylogenetic groups, and involves diverse mechanisms. These findings underscore the overlooked plasticity of genome integrity, and reveal significant gaps in our understanding of why PDE has evolved repeatedly and is maintained across the Tree of Life. This conference is designed to present the latest research on the mechanisms and evolution of PDE - from the molecular pathways that control genome stability and chromosome segregation, to genomic conflictsand the long-term evolutionary consequences of PDE on population dynamics and species diversification.We also welcome researchers studying related phenomena, such as meiotic drive, B chromosomes, and those that work on the mechanisms and regulation of genome stability, chromosome segregation and germline development. The meeting will address the following key topics: Mechanisms and regulation of genome stability and instability Mechanisms of chromosome segregation and missegregation Genomic conflicts Evolutionary dynamics of programmed DNA elimination Plus d'infos... Tags: Evolutionary biology, Molecular genetics, Molecular evolution, Cell cycle, Meiosis, Mutation, Intragenomic conflict Annonce publiée le 28-03-2026

	Institut Jacques Monod Roscoff, Roscoff, France

Lundi 21 Septembre 2026 0:00

Biologie des Systemes du Cancer | 9e edition


L heterogeneite observee entre les tumeurs de differents patients, et meme entre les cellules cancereuses d'un meme patient, complique considerablement le developpement de traitements. La medecine « personnalisee » ou « de precision » vise a surmonter ce probleme en proposant un traitement adapte a chaque patient, en fonction de son profil genetique individuel et de la signature moleculaire de sa tumeur. Cet objectif ambitieux necessite une caracterisation moleculaire approfondie du cancer chez le patient, a l'aide de technologies a haut debit et de techniques d'imagerie avancees. Beaucoup de donnees multi-echelles sur le cancer deviennent disponibles, mais elles restent encore largement sous-exploitees pour elucider les mecanismes sous-jacents et ainsi guider la stratification des patients et le choix des traitements. L'analyse integrative multimodale des donnees omiques et cliniques offre un fort potentiel pour elucider les bases moleculaires des differents types de cancer. L'integration multimodale des donnees sur la maladie est particulierement prometteuse pour mettre en evidence les relations complexes entre les mecanismes moleculaires qui contribuent collectivement a la maladie. Plus d'infos... Annonce publiée le 18-04-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Helene Martel-Massignac (BDD)

Jeudi 24 Septembre 2026 9:00

CRC Scientific Day 2026


Every year, the Centre de Recherche des Cordeliers organises a scientific day where its young researchers, students and post-docs present their work.Prestigious speakers are also invited to take part.This year, we will be welcoming:This event is open to the entire scientific community. Plus d'infos... Tags: Inquiry, Observation, Science, European Research Council Annonce publiée le 27-02-2026

	Centre de Recherche des Cordeliers

Lundi 28 Septembre 2026 0:00

Developpement amp; Cancer - 16e edition


Le cours est dedie aux connaissances les plus actuelles articulant la biologie du developpement et l etude cellulaire et moleculaire des cancers. Les cretes neurales et les melanomes, depuis leur formation jusqu a leur migration (metastases), ainsi que les cancers pediatriques d'origine embryonnaires tels que les medulloblastomes et neuroblastomes sont pris comme exemples. Le cours beneficie d une approche multidisciplinaire a multiples echelles (embryologie sur des modeles varies, biophysique, biologie cellulaire, transcriptomique, imagerie...). Il aborde egalement des approches therapeutiques et ainsi que la prise en compte des 3R en recherche avec l'invitation des chercheurs developpant des organoides et des modeles animaux alternatifs. Le cours est ponctue par des tables rondes sur les carrieres dans le milieu academique ou dans l industrie,sur la publication d articles scientifiques ainsi que sur l ethique en experimentation animale.Des sessions posters de doctorants sont egalement organises et des prix pour les meilleurs posters seront decernes par les participants aux cours. Plus d'infos... Annonce publiée le 10-04-2026

	Institut Curie Centre de recherche - Orsay - Amphitheatre du Batiment 111

Jeudi 08 Octobre 2026 12:00

Title to come
Yasmine Belkaid


Plus d'infos... Tags: Pasteur Institute, Yasmine Belkaid, Yasmin, Aboubakr Belkaid, Lurie Prize in Biomedical Sciences Annonce publiée le 04-03-2026

	Centre de Recherche des Cordeliers

Mardi 13 Octobre 2026 11:30

EM tomography and membrane remodeling


EM tomography and membrane remodeling Plus d'infos... Tags: Medical imaging, Tomography, Crista, Volumetric Electron Microscopy Annonce publiée le 29-04-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie

Jeudi 15 Octobre 2026 12:00

Title to come
Jeremie Gautheron


Plus d'infos... Tags: Jeremie, Jeremi Annonce publiée le 06-03-2026

	Centre de Recherche des Cordeliers

Jeudi 29 Octobre 2026 9:00

Immune variability across the life course


Invite par: Darragh Duffy Thursday 29th Oct 26 \| Institut Pasteur KEYNOTE SPEAKERS ? Prof. Yasmine Belkaid President of the Institut Pasteur (Paris), Professor Yasmine Belkaid is an internationally recognized immunologist specializing in host-microbiota interactions and tissue immunity. ... Plus d'infos... Tags: Pasteur Institute, Yasmine Belkaid, Microbiology, Microbiomes, Bacteriology, Louis Pasteur, Variability, Human microbiome Annonce publiée le 24-02-2026

	Institut Pasteur Batiment: Duclaux

Lundi 09 Novembre 2026 13:00

Allostery and brain science, a tribute to Jean-Pierre CHANGEUX


Invite par: Pierre-Jean Corringer Plus d'infos... Tags: Jean-Pierre Changeux, Neuroscientists, Allosteric regulation, Jean-Pierre, Ruth Nussinov, DehaeneChangeux model Annonce publiée le 30-04-2026

	Institut Pasteur Batiment Duclaux, salle Amphitheatre,

Lundi 16 Novembre 2026 0:00

8eme edition - Biologie Cellulaire et Cancer


Le 8e cours «?Biologie cellulaire et cancer»?explorera comment les formes biologiques emergent a differentes echelles, de l'organisation intracellulaire jusqu'aux tissus et aux organismes entiers. Il mettra l'accent sur des processus cellulaires cles tels que la dynamique du cytosquelette et le trafic intracellulaire, et sur la maniere dont ces processus faconnent des structures cellulaires complexes. Le cours abordera egalement la formation de patterns, la morphogenese et les comportements collectifs des cellules a l'echelle des tissus, dans le contexte de la mecanobiologie et de la biologie du developpement. Plus d'infos... Annonce publiée le 07-05-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Helene Martel-Massignac (BDD)

Lundi 16 Novembre 2026 0:00

Ctrl+Epi+Edit, Engineering the Epigenome


Epigenome editing is a rapidly emerging field that has the potential to revolutionise genomic medicine by offering new ways to precisely program gene expression and treat a range of diseases. Precision control of the epigenome and gene activity is further unlocking key mechanistic insights into a wide variety of molecular and cellular processes. The potential of epigenome editing technologies for both research and therapeutic applications has thus led to widespread excitement over the last five years, in areas ranging from neurobiology, to high-throughput (epi)genomics to agriculture. As the technologies continue to emerge and the epigenome editing field begins to coalesce, we feel now is the time to bring interdisciplinary experts and leaders in the field together. This will enable, for the first time, epigenome editors and related disciplines to collectively discuss the technology, its applications and ethics, and the exciting scientific insights being generated. Such a symposium will help to accelerate progress in this field by facilitating collaborations between researchers and providing a platform for the dissemination of new discoveries and techniques. It will also help to raise broader awareness of this exciting emerging science and its potential to transform precision medicine. Time and Place The meeting will take place fromNovember 16-17atInstitut Jacques Monodin the heart of Paris, France We will have two half day sessions, and a poster session over cocktails and light bites Key Dates Abstract Submission:October 1, 2026 Registration:November 9, 2026 Invited Speakers ? Gabriella Ficz (QMUL, UK) ? Charles Gersbach (Duke University, USA) ? Jamie Hackett (EMBL Rome, Italy) ? Jake Harris (Cambridge University, UK) ?Angelo Lombardo (San Raffaele University, Italy) ? Reini Luco (Institut Curie, France) ?Mariane Rots (UMCG, Netherlands) ?Edda Schulz (MPI Berlin, Germany) ?Stefan Stricker (Helmholtz Munich, Germany) More speakers will be selected from abstracts! You can find all the informations regarding the symposium, the registration and abstract submission here Flyer of the event: here Plus d'infos... Tags: Epigenetics, Epigenome editing, Edit, Epigenome, Genome editing, Omics Annonce publiée le 10-03-2026

	Institut Jacques Monod Institut Jacques Monod Amphitheatre Buffon, 15 rue Helene Brion, Paris, France

16th 3R meeting

Regulations post-transcriptionnelles des genes - 8e cours

Radiomique : theorie et pratique - 5e edition

Euro-African Congress on the Valorisation of Microbial Genetic Resources - RGM EuroAfrica

"Neurocomputational approaches to goal pursuit, productivity, and self-control in the lab and real life" Cendri HUTCHERSON | Department of Psychology University of Toronto

EVH Annual Meeting 2026

Mechanism of sRNA recognition and regulation by FinO RNA chaperones

Paris Postdoc Seminar - Artur Ruppel

Cytoskeleton club

Novel insights into tissue mechano-adaptation through extracellular matrix sensing Gisou VAN DER GOOT

Webinaire de l'enseignement - Comment lancer des recherches lors d'une epidemie ? avec Michael Casera

«Comprendre le vivant a l'echelle des proteines» Guillaume Chevreux

Webinaire de l'enseignement - Comment lancer des recherches lors d'une epidemie ? avec Michael Casera Michael Casera

Des graisses qui vous veulent du bien : perceptions du gras, sante et plaisirs culinaires Martine Glorian, Vincent Moriniaux, Christine Coudray, Esther Katz, Nicolas Cesard, Christophe Lavelle | FSI-UFR de Biologie, FL-UFR de Geographie, INRAE, MNHN

Titre à venir Bregeon/Hamdane's lab and Diu Nguyen - Group Leader at Barts Cancer Institute, Queen Mary University of London

Titre à venir Bregeon/Hamdane's lab and Diu Nguyen

cterial dihydrouridine synthases and Decrypter l'ARN dans sa complexite : l'apport du sequencage Nanopore Bregeon/Hamdane's lab and Anais Mounier - Oxford Nanopore

Investigating Plasmodium myosins to identify antimalarial targets Julien ROBERT-PAGANIN, UMR144, Institut Curie, Paris

From tumor tissues to autoimmunity: discovery of regulatory DN1 B cells reveals shared pathways of immune regulation. Claudia Mauri

Playing with FIRE: the role of macrophages in development and disease Dr Clare Pridans | Univ. of Edinburgh

Pizz of Science - Title to come

Discovering brain circuits that change seasonally. Giacomo Maddaloni | Institut de Psychiatrie et Neurosciences de Paris (IPNP)

The emergence of the mouse pluripotent epiblast Claire Chazaud

Caracterisation genetique et moleculaire d'un cluster de trois snoRNAs impliques dans le metabolisme, la neurodegenerescence et la longevite chez la drosophile. Theo Gauvrit | NeuroPSI - Unverite Paris-Saclay

TBA Helene de

Seminar : Human mucosal and lymph nodeimmunobiology guiding development of herpesviral and HIV vaccines Tony Cunningham

Kinetic Solubility as a Principle of Cellular Organization Simon ALBERTI

How to build a molecular motor? Elucidating the molecular mechanism of assembly of the bacterial flagellum

Innate control of neuronal activity and neuroinflammation by microglia Dr Anne Schaefer | Max Planck Institute for Biology of Ageing

Thirteenth Symposium on Biology of Decision Making

Physical exclusion of heterochromatin at nuclear pores maintain global chromatin organization Dr Charlene Boumendil | Igh

How do plant cell communicate ? Emmanuelle BAYER

Beckman-Coulter Workshop Beckman-Coulter

SpatiotemporalEmergence of Somatosensory Neuron Diversity Navajas Acedo

"Alzheimer'S Disease: Amyloid Biology and Fluid Biomarkers " Mathias JUCKER | University of Tubingen Department Cell Biology of Neurological Diseases

22nd annual meeting of the Neural Network Development club

Chromatin architecture in Archaea - insights from cryo-EM and cryo-ET

TBA Dr Homaira Nawabi | Institut des Neurosciences, Grenoble

Optique adaptative en microscopie de fluorescence a 2 photons pour la neuro-imagerie fonctionnelle chez la souris Alice GUILLAUME-MANCA

Advanced technologies for protein biomarker discovery Aurelie Mouka

Air Pollution impact on the Resolution of Inflammation in Mucoviscidosis (cystic fibrosis) airway disease Maëlys BORN-BONY (Institut Mondor de Recherche Biomédicale, Créteil)

Imaging the Brain: New Probes & Approaches

Revealing the Secrets of Ovulation Christopher Thomas

EXPANDing Immune Cells and their Tumor Antigens during Checkpoint Immunotherapy Diether Lambrechts

How Geometry Drives Collective Cell Migration Teck Lim

Grand challenges in vector-borne diseases

Epigenetic regulation in development and disease Alexander Meissner

Why neuroscientists love the Head Direction system Desdemona Fricker | SPPIN, Universite Paris Cite

Cancers gynecologiques : de la pratique clinique a la biologie

From AMR to Emerging Threats: Understanding Pathogens for Effective Control

Scientific lectures: May The Force Be With You! Piezo Channels in Mechanosensory Biology Ardem Patapoutian | Department of Neuroscience, Scripps Research - Presidential Endowed Chair

"CANCELLED" Dr Laurent Seugnet

TBA Dr Annika Keller | University Hospital Zurich

Staphylococcus epidermidis DnaK alters biofilm formation and proteome in S. aureus CIP 107093 Yoan Konto-Ghiorghi

Neurobiological mechanisms of social behaviour. Camilla Bellone

"Equivalent learning emerges from distinct population dynamics across brain networks" Flavio DONATO | University of Basel - Biozentrum the center for molecular life sciences

4th nICE Day symposium of Cryo-EM users

TBA | LJP

TBA Dr Guy Bouvier | NeuroPSI

Integration somatosensori-motrice corticale lors de l'apprentissage moteur, etudiee a l'aide d'une interface cerveau-machine en boucle fermee. Alexandre Tolboom | NeuroPSI - Unverite Paris-Saclay

Artificial Intelligence in Biology et Health

Surface-based cell-free platform to characterize host-pathogen interactions Aurore Dupin

From the M1/M2 paradigm, to spatial determinism of tumor-associated macrophageheterogeneity Alexandre Boissonnas

Adaptive immunity to the commensal microbiota Ivanov Ivaylo

"The hippocampal latent diffusion engine: a computational framework for memory, perception, and cognitive dysfunction" Michael BREAKSPEAR | University of New Castle school of Science.

Stroma immunite et cancer

Colloque : Stroma immunite et cancer

Immunity in context: how tissues instruct immune responses

Title to come Miriam Merad

Titre à venir Clement Carre/Laure Teysset's Lab and Reini Luco

Adjusting the timing of mammalian development. Aydan Karslioglu

The many faces of doxorubicin and how to improve it for new cancer therapies Sjaak Neefjes

Mechanoregulation of Cytotoxic Lymphocyte Function Morgan Huse

"Neuromodulation of Brain States" Luis DELECEA | Depart of Psychiatry & Behavorial Sciences Stanford University School of Medicine

Single-molecule mechanics of eukaryotic and bacterial SMC complexes Maxim Molodtsov

TBA Dr Nicolas Renier | ICM

The 11th edition of Start-me up on July 2 et 3, 2026

Title to come Kevin Boye

TBA Dr Jun Nagai | Riken Center for brain science

Harnessing Viral Mimicry in Cancer Vaccines Nicolas VABRET

"Neurocomputational approaches to goal pursuit, productivity, and self-control in the lab and real life"
Cendri HUTCHERSON | Department of Psychology University of Toronto

Novel insights into tissue mechano-adaptation through extracellular matrix sensing
Gisou VAN DER GOOT

«Comprendre le vivant a l'echelle des proteines»
Guillaume Chevreux

Webinaire de l'enseignement - Comment lancer des recherches lors d'une epidemie ? avec Michael Casera
Michael Casera

Des graisses qui vous veulent du bien : perceptions du gras, sante et plaisirs culinaires
Martine Glorian, Vincent Moriniaux, Christine Coudray, Esther Katz, Nicolas Cesard, Christophe Lavelle | FSI-UFR de Biologie, FL-UFR de Geographie, INRAE, MNHN

Titre à venir
Bregeon/Hamdane's lab and Diu Nguyen - Group Leader at Barts Cancer Institute, Queen Mary University of London

Titre à venir
Bregeon/Hamdane's lab and Diu Nguyen

cterial dihydrouridine synthases and Decrypter l'ARN dans sa complexite : l'apport du sequencage Nanopore
Bregeon/Hamdane's lab and Anais Mounier - Oxford Nanopore

Investigating Plasmodium myosins to identify antimalarial targets
Julien ROBERT-PAGANIN, UMR144, Institut Curie, Paris

From tumor tissues to autoimmunity: discovery of regulatory DN1 B cells reveals shared pathways of immune regulation.
Claudia Mauri

Playing with FIRE: the role of macrophages in development and disease
Dr Clare Pridans | Univ. of Edinburgh

Discovering brain circuits that change seasonally.
Giacomo Maddaloni | Institut de Psychiatrie et Neurosciences de Paris (IPNP)

The emergence of the mouse pluripotent epiblast
Claire Chazaud

Caracterisation genetique et moleculaire d'un cluster de trois snoRNAs impliques dans le metabolisme, la neurodegenerescence et la longevite chez la drosophile.
Theo Gauvrit | NeuroPSI - Unverite Paris-Saclay

TBA
Helene de

Seminar : Human mucosal and lymph nodeimmunobiology guiding development of herpesviral and HIV vaccines
Tony Cunningham

Kinetic Solubility as a Principle of Cellular Organization
Simon ALBERTI

Innate control of neuronal activity and neuroinflammation by microglia
Dr Anne Schaefer | Max Planck Institute for Biology of Ageing

Physical exclusion of heterochromatin at nuclear pores maintain global chromatin organization
Dr Charlene Boumendil | Igh

How do plant cell communicate ?
Emmanuelle BAYER

Beckman-Coulter Workshop
Beckman-Coulter

SpatiotemporalEmergence of Somatosensory Neuron Diversity
Navajas Acedo

"Alzheimer'S Disease: Amyloid Biology and Fluid Biomarkers "
Mathias JUCKER | University of Tubingen Department Cell Biology of Neurological Diseases

TBA
Dr Homaira Nawabi | Institut des Neurosciences, Grenoble

Optique adaptative en microscopie de fluorescence a 2 photons pour la neuro-imagerie fonctionnelle chez la souris
Alice GUILLAUME-MANCA

Advanced technologies for protein biomarker discovery
Aurelie Mouka

Air Pollution impact on the Resolution of Inflammation in Mucoviscidosis (cystic fibrosis) airway disease
Maëlys BORN-BONY (Institut Mondor de Recherche Biomédicale, Créteil)

Revealing the Secrets of Ovulation
Christopher Thomas

EXPANDing Immune Cells and their Tumor Antigens during Checkpoint Immunotherapy
Diether Lambrechts

How Geometry Drives Collective Cell Migration
Teck Lim

Epigenetic regulation in development and disease
Alexander Meissner

Why neuroscientists love the Head Direction system
Desdemona Fricker | SPPIN, Universite Paris Cite

Scientific lectures: May The Force Be With You! Piezo Channels in Mechanosensory Biology
Ardem Patapoutian | Department of Neuroscience, Scripps Research - Presidential Endowed Chair

"CANCELLED"
Dr Laurent Seugnet

TBA
Dr Annika Keller | University Hospital Zurich

Staphylococcus epidermidis DnaK alters biofilm formation and proteome in S. aureus CIP 107093
Yoan Konto-Ghiorghi

Neurobiological mechanisms of social behaviour.
Camilla Bellone

"Equivalent learning emerges from distinct population dynamics across brain networks"
Flavio DONATO | University of Basel - Biozentrum the center for molecular life sciences

TBA
| LJP

TBA
Dr Guy Bouvier | NeuroPSI

Integration somatosensori-motrice corticale lors de l'apprentissage moteur, etudiee a l'aide d'une interface cerveau-machine en boucle fermee.
Alexandre Tolboom | NeuroPSI - Unverite Paris-Saclay

Surface-based cell-free platform to characterize host-pathogen interactions
Aurore Dupin

From the M1/M2 paradigm, to spatial determinism of tumor-associated macrophageheterogeneity
Alexandre Boissonnas

Adaptive immunity to the commensal microbiota
Ivanov Ivaylo

"The hippocampal latent diffusion engine: a computational framework for memory, perception, and cognitive dysfunction"
Michael BREAKSPEAR | University of New Castle school of Science.

Title to come
Miriam Merad

Titre à venir
Clement Carre/Laure Teysset's Lab and Reini Luco

Adjusting the timing of mammalian development.
Aydan Karslioglu

The many faces of doxorubicin and how to improve it for new cancer therapies
Sjaak Neefjes

Mechanoregulation of Cytotoxic Lymphocyte Function
Morgan Huse

"Neuromodulation of Brain States"
Luis DELECEA | Depart of Psychiatry & Behavorial Sciences Stanford University School of Medicine

Single-molecule mechanics of eukaryotic and bacterial SMC complexes
Maxim Molodtsov

TBA
Dr Nicolas Renier | ICM

Title to come
Kevin Boye

TBA
Dr Jun Nagai | Riken Center for brain science

Harnessing Viral Mimicry in Cancer Vaccines
Nicolas VABRET

Gliding Motion of Diatoms: Motors, Filaments, and Dynamic Trajectory Control
Stefan Diez

Title to come
Yasmine Belkaid

Title to come
Jeremie Gautheron