Vendredi 25 Septembre 2026 10:00

Genomes and genetics department seminar Marnix H. Medema Deciphering the Chemical Language of Microbiome Interactionsusing Computational Omics


Invite par: Ernest Mordret Plus d'infos... Tags: Genomics, Omics, Medema, Genome, Academic disciplines, Michael Fischbach Annonce publiée le 22-09-2026

	Institut Pasteur Batiment Lwoff, salle Retrovirus,

Vendredi 25 Septembre 2026 11:00

Regulation of replication timing and chromatin architecture by nuclear membrane tethering of Rif
Hisao Masai


Rif1 was originally discovered as a telomere binding factor in yeasts. In mammalian cells, Rif1 was shown not to play major roles in telomere regulation, but to regulate DSB repair and replication stress response. Rif1 was shown to facilitate NHEJ during G1 phase and to play roles in protection of stalled replication fork and in elimination of chromosome entanglements during mitosis. Now it is well established that Rif1 plays a major role in regulation of replication timing (RT). In this seminar, I would like first to describe how we identified Rif1 as a key regulator of RT in fission yeast, which led to recognition of a conserved role of Rif1 as a RT regulator in wide varieties of species. We also showed that Rif1 is a G4 (G-quadruplex) binding protein, and that G4 recognition plays a crucial role in RT regulation at least in fission yeast. A portion of mammalian Rif1 is localized near nuclear periphery and is biochemically fractionated into detergent-resistant membrane fractions. Tagging of endogenous Rif1 with mSG (monomeric StayGold) fluorescent protein revealed that Rif1 associates with nuclear membrane during early/ mid S phase, and dissociates at mid/ late S phase to G2. I would like to discuss our recent findings on how mammalian Rif1 is tethered to nuclear membrane, its role in RT regulation and compartment regulation. We particularly focus on the functions associated with the C-terminal segment (CTD) and a long IDP (intrinsically disordered polypeptides) connecting the N-terminal HEAT/Armadillo repeat sequences and CTD. Plus d'infos... Tags: Branches of biology, Biology, Telomeres, RIF1, Cell cycle, Molecular genetics, Chromosomes, Molecular biology Annonce publiée le 11-09-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie

Vendredi 25 Septembre 2026 11:00

DSCB Seminar - Dr. Fiona Watt, EMBL Heidleberg, Germany - Exploring the epidermal stem cell niche at single cell resolution


Invite par: Laure Bally-Cuif Abstract: In this seminar, I will discuss our current understanding of the stem cell compartment in adult human epidermis, based on lab-based studies and single-cell sequencing of cells isolated directly from the skin. I ... Plus d'infos... Tags: Branches of biology, Biology, Life sciences, Stem cells, Biotechnology, Fiona Watt, Wellcome Trust, Cloning, Epidermis, Stem-cell niche, European Molecular Biology Laboratory Annonce publiée le 19-09-2026

	Institut Pasteur Batiment Monod, salle Amphi Ullmann,

Vendredi 25 Septembre 2026 11:45

Building to understand: Enhancer-Promoter Communication in the Context of Regulatory Landscapes
Christa Buecker


Invitee par l'equipe Greenberg, Christa Buecker (Associate Professor at Max Perutz Labs, University Vienna presentera un seminaire de l'Institut Jacques Monod sur le theme : Building to understand: Enhancer-Promoter Communication in the Context of Regulatory Landscapes Resume : Enhancers can regulate promoters from a distance, but it is still unclear how they establish this communication. Furthermore, multiple enhancers often control the activity of the same gene, yet their interactions remain elusive. We have established a synthetic framework to build regulatory landscapes within the genome of mouse embryonic stem cells to dissect enhancer promoter communication. We have now expanded our toolbox to test enhancer libraries, alone or in combination with other elements, to identify principles of distal gene regulation. Plus d'infos... Tags: Gene expression, Enhancer, Promoter, Eileen Furlong, Enhancer RNA Annonce publiée le 17-08-2026

	Institut Jacques Monod Institut Jacques Monod Salle Francois Jacob, 15 rue Helene Brion, Paris, France

Vendredi 25 Septembre 2026 12:00

Inversions and the Hunt for the Genomic Targets of Selection
Prof. Thomas FLATT


Invite par: EEB External Seminar Series Plus d'infos... Tags: Chromosomes, Chromosomal inversion Annonce publiée le 19-09-2026

	IBENS salle Favard, IBENS 46 rue d'Ulm 75005 Paris

Vendredi 25 Septembre 2026 14:00

L'activite neuronale prenatale est requise pour la formation des compartiments du striatum
Hugues CARTONNET


Invite par: IBENS - Equipe Sonia GAREL Plus d'infos... Annonce publiée le 12-09-2026

	IBENS salle Favard, IBENS 46 rue d'Ulm 75005 Paris

Lundi 28 Septembre 2026 0:00

Developpement amp; Cancer - 16e edition


Le cours est dedie aux connaissances les plus actuelles articulant la biologie du developpement et l etude cellulaire et moleculaire des cancers. Les cretes neurales et les melanomes, depuis leur formation jusqu a leur migration (metastases), ainsi que les cancers pediatriques d'origine embryonnaires tels que les medulloblastomes et neuroblastomes sont pris comme exemples. Le cours beneficie d une approche multidisciplinaire a multiples echelles (embryologie sur des modeles varies, biophysique, biologie cellulaire, transcriptomique, imagerie...). Il aborde egalement des approches therapeutiques et ainsi que la prise en compte des 3R en recherche avec l'invitation des chercheurs developpant des organoides et des modeles animaux alternatifs. Le cours est ponctue par des tables rondes sur les carrieres dans le milieu academique ou dans l industrie,sur la publication d articles scientifiques ainsi que sur l ethique en experimentation animale.Des sessions posters de doctorants sont egalement organises et des prix pour les meilleurs posters seront decernes par les participants aux cours. Plus d'infos... Annonce publiée le 10-04-2026

	Institut Curie Centre de recherche - Orsay - Amphitheatre du Batiment 111

Lundi 28 Septembre 2026 8:00

International symposium of the Leukemia Institute
Chloe Baron, Lina Benajiba, Nicolas Boissel, Marcus Buschbeck, Hugues de The, John Dick, Alexandre Fagnan, Brunangelo Falini, Margaret Goodell, Olivier Hermine, David Michonneau, Diana Passaro, Emmanuelle Passegue, Francoise Porteu, Kevin Rouault-Pierre, Michel Sadelain, Marie Sebert, Jean Soulier, Ulrich Steidl, Alexander Waclawiczek, Eunice Wang, Marcin Wlodarski | plusieurs sites


Invite par: the Leukemia Institute Plus d'infos... Tags: Leukemia Annonce publiée le 18-06-2026

	College de France amphitheatre Marguerite de Navarre du College de France

Lundi 28 Septembre 2026 11:00

Immune cell compartmentalization and interactions in lymph nodes and spleen, with a focus on stromal fibroblasts
Sanjiv A. Luther


The architecture of secondary lymphoid organs is key to mount effective adaptive immunity and it depends on fibroblastic reticular cells (FRCs), which form niches guiding immune cell positioning. Yet, the molecular cues driving FRC subset differentiation remain unclear. Upon identification of a Notch signaling signature within various FRC subsets we combined mouse genetics, transcriptomic profiling, flow cytometric analysis and microscopic imaging to dissect the importance of this pathway in lymph node (LN) FRCs. Notch2, targeted via CCL19-Cre, proved essential for postnatal development of CCL19hi T zone FRCs (TRCs) and their identity maintenance. These cells form a CCL19 gradient that organizes a central T zone enriched in CCR7? CD8? T cells and Xcr1? cDC1s. This spatial organization and Notch activity in TRCs were found to be conserved in human LNs. Mechanistically, homeostatic mature DCs, expressing high Jagged-1, activate Notch2 signaling in TRCs and drive their differentiation and CCL19 expression. Disruption of this loop impairs T zone structure and CD8? T cell responses. CCL19 has a non-redundant role in establishing this niche (Alouche et al., Immunity 2026). Unpublished data will also be presented on the role of Notch2 signaling in splenic fibroblast development and their role in B cell follicle versus T zone compartmentalization, along with its implication for adaptive immunity Plus d'infos... Tags: Branches of biology, Medical specialties, Immune system, Cell biology, Cytokines, Lymphatic system, Chemokine receptors, C-C chemokine receptor type 7, Lymph node, XCR1, Lymphocyte, CCL19 Annonce publiée le 09-09-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e

Lundi 28 Septembre 2026 11:00

"From Cell To Systems: Navigating The Complex Landscape Of Autism Spectrum Disorders"
Gaia Novarino | Institute Of Science And Technology Austria


Autism spectrum disorders (ASD) are a heterogeneous group of disorders rooted in genetic bases. Although genetic studies have identified many ASD-risk genes over the past few years, it remains essentially unknown whether mutations in different genes result in similar molecular and cellular states within the brain. Over the past years, we have generated a large cohort of ASD mouse models carrying mutations in top, high-risk ASD genes. The cohort includes 11 mouse lines and span chromatin remodelers, ubiquitin-related genes, metabolically relevant genes, and synaptic proteins. Employing these validated mouse models, we performed simultaneous single nucleus RNA and ATAC sequencing across brain regions, developmental stages, and sexes, totaling over 300 samples. We achieved this by pioneering an approach that allowed us to sequence RNA and DNA from the same nucleus on a large scale. With this unique dataset, we could address precise questions regarding convergence and divergences across different ASD models, time windows affected, and sex differences. Plus d'infos... Tags: Branches of biology, Psychiatry, Psychiatric diagnosis, Abnormal psychology, Autism, Pervasive developmental disorders, Developmental neuroscience, Developmental psychology, Epigenetics of autism, Heritability of autism Annonce publiée le 10-09-2026

	I. Cerveau et de la Moelle Please join the conference in Paris Brain Institute auditorium.

Lundi 28 Septembre 2026 14:00

Modulation of socio-sexual behavior by astrocytic ?7nAChR-JAK2-STAT3 signaling in the ventral hippocampus of male mice.
Tom Lakomy | NeuroPSI - Unverite Paris-Saclay


Plus d'infos... Tags: Branches of biology, Biology, Signal transduction, Tyrosine kinases, Gene expression, Transcription factors, Janus kinase 2, Astrocyte, Hippocampus, STAT3, Seahorse Annonce publiée le 12-09-2026

	NeuroPSI

Mardi 29 Septembre 2026 0:00

Seminaire interne: TBA


- Plus d'infos... Annonce publiée le 08-06-2026

	Laboratoire Jean Perrin Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e, salle 407

Mardi 29 Septembre 2026 9:30

Beyond Epigenetics: Chromatin as a Metabolic Organelle
Siavash Kurdistani


Ancestral histones originated before many of the structural and regulatory functions now associated with chromatin, as well as before much of the machinery that writes, removes, and interprets histone modifications. We therefore reasoned that histones might possess an older biochemical activity that provided a selective advantage early in their evolution. We discovered that histone H3 functions as a copper reductase enzyme, converting Cu2+to bioavailable Cu1+. I will discuss how this enzymatic activity provides a new framework for understanding the evolution and function of the nucleosome, the potential role of histones in eukaryogenesis, and how histone mutations may contribute to human disease. Plus d'infos... Tags: Branches of biology, Biology, Genetics, Epigenetics, Proteins, Molecular genetics, Histone, Chromatin, Chromatin remodeling, Histone methylation Annonce publiée le 09-09-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie

Mardi 29 Septembre 2026 10:00

A TREEtise on ionotropic glutamate receptors
Dr. Timothy LYNAGH


Invite par: IBENS Neuroscience Seminar Abstract: We tend to divide ionotropic glutamate receptors into fast synaptic detectors (AMPA receptors), multimodal modifiers (NMDA receptors), or strange cousins (delta receptors). But this view belies substantial variation in their functional repertoires, is difficult to project onto various animal models that have vastly different genes, and leaves several biophysical and physiological mysteries unsolved. We explored the evolution of ionotropic glutamate receptors using phylogenetics and functional characterization of receptors from diverse animals. We find that AMPA receptors repeatedly evolve complexity and diversity in different types of animals yet converge on remarkably similar biophysical function. We find that NMDA receptors have vastly different functional properties in certain invertebrates, which in turn uncovers mechanisms behind mammalian NMDA receptors' requirement for multiple transmitters. And compared to vertebrates, it turns out that delta receptors in most animals are more normal than expected in terms of channel gating, but even weirder in terms of ligand preferences. Plus d'infos... Tags: Branches of biology, Ionotropic glutamate receptors, Glutamate, Protein families, Cell signaling, Membrane proteins, Glutamate receptor, NMDA receptor, Ligand-gated ion channel, Receptor, AMPA receptor, Neurotransmitter receptor Annonce publiée le 19-09-2026

	IBENS salle Favard, IBENS 46 rue d'Ulm 75005 Paris

Mardi 29 Septembre 2026 11:00

Thermodynamics of collective behavior
Nikta Fakhri


Invitee par l'equipe Ladoux/Mege, Nikta Fakhri (Massachusetts Institute of Technology (MIT) ) presentera un seminaire de l'Institut Jacques Monod sur le theme : Thermodynamics of collective behavior Resume : Living systems are active matter: assemblies of molecules, cells, and organisms that continuously consume energy to generate motion, forces, and collective organization. This persistent dissipation breaks time-reversal symmetry, giving rise to a physical arrow of time that shapes the behavior of living matter. In this talk, I will explore irreversibility not merely as a signature of biological activity, but as a resource for collective organization and reliable decision-making. Drawing on experiments and theory, I will show how nonequilibrium interactions and probability flows shape collective response and direct transitions between states, revealing thermodynamic constraints linking accuracy, speed, and energetic cost. From living chiral crystals and odd elasticity to biological decision-making and multicellular organization, this work advances a thermodynamic understanding of how living systems organize and navigate possible futures. Plus d'infos... Tags: Physical sciences, Natural sciences, Physics, Thermodynamics, Non-equilibrium thermodynamics, Irreversible process, Active matter, Thermodynamic system, Thermodynamic state, Thermodynamic equilibrium Annonce publiée le 17-09-2026

	Institut Jacques Monod Batiment Condorcet Amphitheatre Pierre Gilles de Gennes, 4 rue Elsa Morante, Paris, France

Mardi 29 Septembre 2026 11:00

Seminaire interne: Exploring the head direction system in Danionella Cerebrum / TBA
Par Manon


Manon Carriegrave;re : Exploring the head direction system in Danionella Cerebrum Head direction (HD) cells are neurons that activate maximally when an animal faces a specific, cell-dependent direction. Together, they operate as a ldquo;neuronal compassrdquo; for spatial representation. HD circuits are thought to possess the architecture of ring attractors, networks with local excitation and global inhibition that generate a stable bump of activity encoding head orientation. What plasticity rules orchestrate the maturation of such subtle circuits during development remains an open question. As a first step, we aim to identify and characterize HD circuits in Danionella cerebrum (DC), a small, quasi-transparent freshwater fish that enables whole-brain calci um imaging across development. Talk 2: TBA Plus d'infos... Tags: Danionella, Cerebrum, Brain Annonce publiée le 23-09-2026

	Laboratoire Jean Perrin Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e, salle 407

Mardi 29 Septembre 2026 11:30

Noradrenergic modulation of dopaminergic neurons in the dorsal raphe nucleus contributes to stress-induced reward insensitivity
Dr Raffaella Tonini | Institut Italien de Tecnologie


Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 10-06-2026

	College de France au College de France Salle D2 11 place Marcelin Berthelot - 75005 Paris

Mardi 29 Septembre 2026 14:00

Mecanismes moleculaires et pharmacologie des recepteurs GluD, une famille atypique de recepteurs ionotropiques au glutamate.
Julia DORIA


Invite par: IBENS - Equipe Pierre PAOLETTI Plus d'infos... Annonce publiée le 18-09-2026

	IBENS salle Favard, IBENS 46 rue d'Ulm 75005 Paris

Mercredi 30 Septembre 2026 9:00

Amplifying Funds in Infection Biology - 2nd International Symposium


Invite par: Mallory Perrin-Wolff Stengthening Institut Pasteur's european partnerships, which can be a source of multiple scientific opportunities as well as new funding, is one of the key priorities of the Pasteur 2030 strategic plan.In this spirit, Institut ... Plus d'infos... Tags: Epidemiology, COVID-19 pandemic in France, Pasteur Institute, Louis Pasteur, Infection Annonce publiée le 08-07-2026

	Institut Pasteur Batiment: Duclaux Salle: Duclaux Lecture Hall

Mercredi 30 Septembre 2026 11:30

A mathematical framework for understanding the timing of cell decisions: from developmental tempo to molecular mechanisms of gene regulation
Ruben Perez-Carrasco


Cells make decisions across developmental biology, immunology, and synthetic biology. Yet, while the timing of these decisions can be as important as their outcome, mathematical models often focus primarily on stable cell states. In this talk, I will present a mathematical framework based on orbital equivalence to identify molecular mechanisms that can control the speed of cellular decisions while preserving their underlying dynamics. I will first address developmental tempo, where embryos from different species execute remarkably similar genetic programmes at different speeds. I will then turn to gene regulatory networks, showing how critical slowing down and transient dynamics can regulate decision times, and how analysing different network topologies can reveal design principles for controlling dynamical speed in synthetic and natural systems. Plus d'infos... Tags: Systems biology, Evolutionary developmental biology, Gene expression, Gene regulatory network, Networks, Biology, Eileen Furlong Annonce publiée le 02-09-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie

Mercredi 30 Septembre 2026 12:00

Department of Parasites and Insect Vectors Seminar : Joana Faria The architecture of disguise: how Trypanosoma brucei expresses a single variant surface antigen


Invite par: Jessica Bryant Trypanosoma brucei survives in the mammalian hosts by continuously altering its dense Variant Surface Glycoprotein (VSG) coat. Central to this antigenic variation is monogenic expression: the exclusive transcription of a single VSG allele from a vast ... Plus d'infos... Tags: Trypanosomatida, Parasitology, African trypanosomiasis, Trypanosoma brucei, Variant surface glycoprotein, Antigenic variation, Trypanosoma, VSG, Disease vector, Parasitism Annonce publiée le 31-07-2026

	Institut Pasteur Batiment Lwoff, salle Retrovirus,

Jeudi 01 Octobre 2026 9:30

Redundant microtubule abscission mechanisms buffer mechanical heterogeneities
Agathe CHAIGNE


In the final step of cell division, cytokinesis, the cytoplasm is partitioned in two, forming a cytoplasmic bridge between the daughter cells. Typically, cytokinesis is followed by abscission, the physical severing of the bridge. The severing of the membrane during abscission is mediated by the ESCRT-III machinery, which also recruits microtubule severing proteins to remove the microtubules of the bridge. Pulling forces on the bridge have been proposed to act as regulators of abscission by influencing the localization of the ESCRT-III complex. However, how forces are integrated by cells during abscission in a developmental context remains elusive. Here, we use pluripotent stem cells, where abscission is slow keeping the two daughter cells connected for hours, to show that the cytoskeleton buffers mechanical heterogeneities to ensure abscission. We show that cells can cut their microtubules in two distinct ways. Slow abscission is associated with an asymmetric cut in the microtubule lattice, while during fast abscission, the microtubules are gradually removed on both sides of the bridge. We show that the contractility of the actin cortex mediates this choice between the two abscission modes through modulation of the master kinase Aurora B. Finally, the choice between the abscission mode depends on and impacts fate choice dynamics. Plus d'infos... Tags: Cell biology, Proteins, Cell cycle, Mitosis, Cytoskeleton, Cytokinesis, ESCRT, Microtubule, Abscission, Aster, Cell cortex, Formins Annonce publiée le 08-08-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie

Jeudi 01 Octobre 2026 14:00

Des sifflements a la communication: vers une comprehension computationnelle des signaux acoustiques des dauphins
Faadil MUSTUN


Invite par: IBENS - Equipe SUMBRE Plus d'infos... Annonce publiée le 09-09-2026

	IBENS salle Favard, IBENS 46 rue d'Ulm 75005 Paris

Vendredi 02 Octobre 2026 0:00

? Quand la science rencontre le patrimoine a l#039;Institut Cochin venez voir le style Pint of Science
Thalie Law


Pour démarrer la semaine fête de la Science et dans le cadre de ses actions de médiation scientifique, nous avons le plaisir d’accueillir Thalie Law pour un séminaire intitulé : ? « Et si Law pouvait sauver le verre ? » Comment étudier l’altération des verres anciens ? Et comment les sciences physico-chimiques peuvent-elles contribuer à mieux comprendre et préserver notre patrimoine ? ? ? ?? Docteure en physico-chimie, Thalie Law a réalisé entre 2022 et 2025 une thèse consacrée à l’altération des verres anciens, au sein de l’IRCP et du C2RMF. En parallèle de son doctorat, elle a été médiatrice scientifique aux Étincelles du Palais de la découverte, associant ainsi recherche et transmission des sciences auprès du public. Elle poursuit aujourd’hui ses recherches en postdoctorat au C2RMF et à l’ Institut national d'histoire de l'art, où elle travaille sur un projet consacré à l’archivage numérique des œuvres des Della Robbia. Un séminaire à la croisée de la recherche, de la médiation scientifique et de la conservation du patrimoine, pour découvrir la science sous un angle différent ! Plus d'infos... Annonce publiée le 23-09-2026

	Institut Cochin Salle Rosalind Franklin

Vendredi 02 Octobre 2026 11:30

Complex Networks.
Thiago de Lima Prado | Department of Physics, Federal University of Parana, Curitiba, Parana, Brazil


Plus d'infos... Annonce publiée le 28-07-2026

	NeuroPSI Salle de conference Albe-Fessard

Vendredi 02 Octobre 2026 17:00

Inferring collective dynamics from social animals to neuronal networks
Xiaowen Chen | LPENS, ENS


The title and abstract of this talk will be announced soon. Plus d'infos... Tags: Xiaowen, Chen, 499 deaths, Yuan Xie, Chinese drama television series, Chinese television series, Emperor Xiaowen of Northern Wei Annonce publiée le 26-08-2026

	Neural Networking Night pub Le Piano Vache - 8 Rue Laplace, 75005 Paris

Lundi 05 Octobre 2026 0:00

?Les Kraneuses qui Tetonnent? 5 femmes, 5 portraits pour sensibiliser au cancer du sein chez les femmes jeunes


Transformer l'alopecie en œuvre d'art Certains traitements par chimiotherapie peuvent entrainer une perte des poils de tout le corps et du visage, en particulier des cheveux : c'est ce qu'on appelle une alopecie. Effet indesirable des traitements souvent mal vecu, la chute des cheveux peut representer une atteinte a l'image de soi. Face a ce constat, l'association Jeune&Rose et Maquille mon Krane ont imagine « Les Kraneuses qui Tetonnent » : une initiative artistique qui vise a transformer les cranes et bustes de patientes en situation d'alopecie en œuvres d'art, pour sensibiliser le plus grand nombre a un sujet encore trop souvent tabou. Depuis 2024, maquillees puis photographiees, ces femmes volontaires s'exposent ainsi pour mettre en lumiere leur parcours face au cancer. Cinq nouveaux portraits, portes par l'Institut Curie et l'Institut des Cancers des Femmes En 2026, pour cette troisieme saison, les deux associations s'associent a l'Institut des Cancers des Femmes pour mettre en lumiere 5 nouveaux portraits de femmes atteintes d'un cancer du sein et soignees a l'Institut Curie. Elles s'exposeront tout au long du mois d'octobre dans plusieurs lieux parisiens « Le cancer du sein reste rare chez les femmes jeunes, mais son incidence augmente. Plus de 3 000 femmes de moins de 40 ans sont diagnostiquees chaque annee en France. Parce qu'elles restent minoritaires parmi les patientes atteintes d'un cancer du sein, cette realite est encore trop peu connue. Cette exposition contribue justement a la rendre visible.» explique la Dre Florence Coussy, gynecologue et oncologue medicale a l'Institut Curie « Nous avons a cœur d'accompagner les patientes sur le chemin de l'acceptation en leur permettant de se reapproprier, via l'art du maquillage, une image de soi stigmatisante. Notre volonte est de mettre en valeur une forme de beaute atypique encore trop souvent consideree comme tabou, de questionner la feminite et le rapport a la maladie et de changer le regard du grand public en l'incitant a aller au-dela des apparences.» indique Caroline Pescher, co-fondatrice Maquille Mon Krane et Ambassadrice Jeune&Rose « Avec Jeune&Rose, nous proposons un accompagnement des femmes jeunes touchees par un cancer du sein en prenant en compte leurs problematiques propres : grossesse, vie de famille, feminite et retour a la vie sociale et professionnelle. Le projet des Kraneuses qui Tetonnent s'inscrit pleinement dans cette demarche et est au cœur de notre programme Teleteton. Ces portraits contribuent a changer le regard sur le cancer du sein. Au travers de l'exposition, elles transmettent aussi un message de prevention : connaitre ses seins est essentiel en complement du suivi gynecologique et medical.» affirme Melanie Courtier, co-fondatrice et Directrice generale Jeune&Rose Village associatif Un village associatif se tiendra le 7 octobre 2026, de 13h a 17h30, reunissant aux cotes de l'Institut des Cancers des Femmes plusieurs associations engagees dans l'accompagnement des patientes (Jeune&Rose, Aida, Patients en Reseau, la Ligue contre le cancer, Imagyn, Geneticancer, les Seintinelles, GPS Cancer), ainsi que des professionnels de la CPAM, du CRCDC et le Centre de Sante du Square de la Mutualite pour sensibiliser les femmes a la prevention et au depistage. Agenda : une exposition itinerante dans tout Paris L'exposition suivra un parcours dans plusieurs lieux parisiens tout au long du mois de l'automne : ? Inauguration le 5 octobre, salle Pierrotet, 18h30, a la Mairie du Ve arrondissement, avec le soutien de Madame la Maire, Florence Berthout, exposition visible jusqu'au 17 octobre. ? Du 5 au 18 octobre sur le parvis du Pantheon, avec le soutien de JCDecaux. ? Du 5 au 30 octobre sur les grilles du Musee Curie, rue Pierre & Marie Curie et rue d'Ulm. ? Du 5 au 30 octobre dans l'espace de consultation de l'hopital de l'Institut Curie a Saint Cloud. ? Du 3 novembre au 27 novembre sur les grilles du jardin de Reuilly (Paris 12e), avec le soutien de la Mairie du XIIe arrondissement. ? Du 12 octobre au 17 decembre sur les grilles du jardin de l'Agora de la Sante, rue Boucry (Paris 18e). ? Du 16 au 27 novembre a la Cite Audacieuse (Paris 6e), de la Fondation des Femmes, avec le soutien de la senatrice Dominique Verien, presidente de la Delegation aux droits des femmes. Cette exposition est soutenue par JCDecaux et la Mairie du 5e arrondissement. Plus d'infos... Annonce publiée le 15-09-2026

	Institut Curie

Lundi 05 Octobre 2026 0:00

Neurepiomics 2026


Founded by leading researchers, Professors Stephanie Debette and Sudha Seshadri, this annual event brings together a vibrant global community for an immersive, cross?disciplinary training experience. Plus d'infos... Tags: Seshadri Annonce publiée le 05-06-2026

	I. Cerveau et de la Moelle Institut du cerveau

Lundi 05 Octobre 2026 12:00

Strategies for enhancing toxic protein clearance in neurodegenerative diseases
Dr. David Rubinsztein | Cambridge Institute for Medical Research and UK Dementia Research Institute, University of Cambridge


Invite par: Dr T Galli Intracellular protein aggregation is a feature of many late-onset neurodegenerative diseases, including Parkinson&'s disease, tauopathies (including Alzheimer&'s disease and frontotemporal dementia), and polyglutamine expansion diseases (like Huntington&'s disease). Many of these mutant proteins cause disease via toxic gain-of-function mechanisms. Therefore, the factors regulating their clearance are crucial for understanding disease pathogenesis and for developing rational therapeutic strategies. We showed that autophagy induction reduces the levels of proteins causing Huntington&'s disease, Parkinson&'s disease and forms of dementia and attenuates their toxicity in cellular/neuronal, Drosophila, zebrafish and mouse models. In this talk, I will discuss how understanding the processes regulating autophagosome formation have helped us delineate the functions of BIN1, a major Alzheimer&'s disease risk gene. I will describe how our work on cellular nutrient sensing has helped us understand how autophagy is compromised by alpha-synuclein, a major toxic protein causing Parkinson&'s disease. Finally, I will describe recent work suggesting that one may also be able to lower the levels of such intracellular proteins by stimulating lysosomal secretion and that there may be FDAapproved drugs that can be used to ameliorate tauopathies via this mechanism. Plus d'infos... Annonce publiée le 22-09-2026

	Institut de Psychiatrie et Neurosciences de Paris Room D Levy, Institut de Psychiatrie et Neurosciences de Paris (IPNP) UMR 1266 INSERM - Universite Paris Cite, 102-108 Rue de la Sante - 75014 Paris

Mardi 06 Octobre 2026 0:00

Effects of Calreticulin mutations on HLA Class I expression and function in Myeloproliferative Neoplasms
Pr Malini Raghavan


Abstract: Myeloproliferative neoplasms (MPN) can result from mutations in the calreticulin (CRT) gene (CALR), which encodes a chaperone important for human leukocyte antigen (HLA) class I assembly. CRISPR knock-in cell lines expressing mutant and endogenous CALR preserve or induce surface HLA class I levels in an allele-dependent manner. In contrast, cell lines lacking wild-type CRT display allele-dependent reductions in HLA class I expression, which mutant CRTs fail to rescue. Correspondingly, HLA class I expression is generally in the normal range in platelets and monocytes from myeloproliferative neoplasm (MPN) patients with heterozygous CALR mutations, whereas rare cases with homozygous CALR mutations show lower expression. Wild type CRT deficiency with or without MPN mutant expression induces NK cell activation. These studies demonstrate varying CRT dependencies of HLA class I expression, identify specific HLA class I alleles and homozygous CALR mutations as prerequisites for low HLA class I expression in MPN and illustrate the potential for inducing NK cell-mediated immunity in some patients. Furthermore, the maintenance/induction of surface HLA class I levels in cells with heterozygous CALR mutations highlights the prospect for harnessing CD8+ T cell-driven immune responses against MPN. Plus d'infos... Tags: Immune system, Branches of biology, Medical specialties, Organ systems, Calreticulin, Myeloproliferative neoplasm, Human leukocyte antigen, Natural killer cell, HLA-A, HLA-G Annonce publiée le 24-09-2026

	Institut Cochin Salle Schapira

Mardi 06 Octobre 2026 0:00

TBA
Anke Lindner


TBA Plus d'infos... Tags: Stratiomyidae, Lindner, Anke, Draft:Valley Vista Elementary School, Carl Lindner Annonce publiée le 07-09-2026

	Laboratoire Jean Perrin Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407

Mardi 06 Octobre 2026 11:45

Paris Postdoc Seminar - Sophie Peron


Invitee par l'Institut Jacques Monod, Sophie Peron ( Institut Imagine, Team somatic mosaicism in neurodevelopment and disease, Paris) presentera un Paris Postdoc seminar sur le theme : Coordination between cell cycle and differentiation in planarian stem cells Resume : Planarians have extensive regenerative abilities fuelled by a population of adult stem cells. Those cells also constantly proliferate and differentiate into dozens of different cell types to maintain tissue homeostasis. However, how cell fate acquisition is coordinated with cell cycle progression remains poorly understood. We choose to address this question in Schmidtea mediterranea using single cell transcriptomics. We generated scRNA-seq datasets from cells enriched for 2C or 4C DNA content and from animals subjected to RNAi against the cell cycle regulators cdh1 and h2b. Our analyses show that progenitor populations across multiple lineages contain actively cycling cells and that lineage commitment occurs at different stages depending on the cell type. Comparative analyses reveal that Schmidtea possesses a simplified repertoire of canonical cell cycle regulators, consistent with a central role for cdh1 in controlling cell cycle exit. Functional perturbation of cdh1 demonstrates that cell cycle exit is needed for differentiation but not for lineage specification. Together, these findings provide new insights into how cell cycle regulation is coordinated with lineage commitment and differentiation in planarian stem cells. Plus d'infos... Tags: Branches of biology, Biology, Life sciences, Biotechnology, Induced stem cells, Animal models, Developmental biology, Stem cells, Planarian, Cell cycle, Adult stem cell, Schmidtea mediterranea Annonce publiée le 21-09-2026

	Institut Jacques Monod Institut Jacques Monod Salle Francois Jacob, 15 rue Helene Brion, Paris, France

Mardi 06 Octobre 2026 13:00

Looking Back, Looking Forward: Reflections on a Career in Neuroscience.
Daniel Shulz | A career retrospective lecture: Daniel SHULZ Directeur de Recherche Emerite


Plus d'infos... Tags: Albums, Reflections Annonce publiée le 17-09-2026

	NeuroPSI Salle de conference Albe-Fessard

Mercredi 07 Octobre 2026 0:00

Noninvasive Brain Stimulation Intensive Hands-On Training for Scientists and Clinician Scientists


Participants will explore established techniques such as TMS and tES (tDCS, tACS and tRNS), as well as emerging approaches including tTIS and tFUS. The course aims to provide a solid understanding of the physical, physiological and neurobiological principles underlying NIBS, together with their safety, strengths and limitations. Through intensive small-group hands-on interactive sessions, participants will learn to operate NIBS technologies, address practical challenges of stimulation targeting and dosing, and implement reproducible protocols. Students will be familiarised on how to combine NIBS with EEG, MRI/fMRI, PET and robotic neuronavigation to monitor and validate target and network engagement and investigate causal mechanisms of brain function. Finally, the course will provide participants with the methodological foundations needed to design rigorous experimental, preclinical and clinical NIBS studies addressing cognition, brain disorders and rehabilitation, while considering essential ethical and safety requirements. Morning lectures will provide the theoretical foundations, while afternoon small-group sessions will offer intensive hands-on experience with NIBS technologies and equipment. The programme covers fundamental, cognitive, translational and clinical applications, from causal brain mapping and network modulation to rehabilitation in neurological disorders. Plus d'infos... Tags: Branches of biology, Neurophysiology, Neuroscience, Medicine, Neurostimulation, Neurotechnology, Braincomputer interfacing, NIBS, Transcranial random noise stimulation, Neuronavigation, Electroencephalography, Tacs Annonce publiée le 24-09-2026

	I. Cerveau et de la Moelle The Noninvasive Brain Stimulation Intensive Hands-On Training will take place on 7, 8 and 9 October 2026 at the Paris Brain Institute (ICM), Paris, France.The course is designed for a selected cohort of 20 participants, ranging from Master's students and PhD candidates to postdoctoral researchers, clinician-scientists and young PIs. All teaching will be conducted in English. The three-day programme combines morning lectures, afternoon hands-on laboratory sessions in small groups, keynote lectures, participant presentations and scientific discussions. The practical sessions will be organised in groups of approximately 10 participants to maximise interaction with instructors and access to the equipment. A course dinner will also provide an opportunity for informal scientific exchange and networking.

Mercredi 07 Octobre 2026 11:30

Investigating biomolecular condensates using molecular simulations at multiple resolutions
Alessandro Barducci


Biomolecular condensates have emerged as an important principle of cellular organization, providing dynamic compartments whose composition and properties arise from a complex interplay of molecular interactions. Their intrinsically heterogeneous and dynamic nature, however, makes it difficult to connect microscopic mechanisms to their collective behavior and biological function. In this talk, I will discuss how molecular simulations at different resolutions can help bridge these scales. I will present recent work from our group illustrating how atomistic and coarse-grained approaches can be combined to investigate the assembly, internal organization, and regulation of protein and protein-RNA condensates. Beyond providing structural and dynamical information that is difficult to access experimentally, these models can help identify the molecular determinants of phase behavior and clarify how condensate properties emerge from interactions among their components. Plus d'infos... Tags: Computational chemistry, Branches of biology, Biomolecular condensate, Organelles, Molecular modelling, Protein complex, Natural sciences, Biology Annonce publiée le 08-09-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie

Jeudi 08 Octobre 2026 9:00

Tiny Vectors, Major Threats: A Deep Dive into Tick-Borne Infections


Invite par: Sarah Bonnet October 8 - Room Jules Bordet Program will be annouced soon. Labex IBEID Plus d'infos... Tags: Disease transmission, Disease vector, Epidemiology, Parasitology, Tick Annonce publiée le 10-07-2026

	Institut Pasteur Batiment: Metchnikoff Salle: Jules Bordet

Jeudi 08 Octobre 2026 12:00

Title to come
Yasmine Belkaid


Plus d'infos... Tags: Pasteur Institute, Yasmine Belkaid, Yasmin, Aboubakr Belkaid, Lurie Prize in Biomedical Sciences Annonce publiée le 04-03-2026

	Centre de Recherche des Cordeliers

Jeudi 08 Octobre 2026 14:00

Focusing on retinal regeneration.
Jingxian Lun | NeuroPSI - Unverite Paris-Saclay


Plus d'infos... Tags: Vision, Senses, Perception, Light, Blindness, Retinal regeneration, Retina, Thomas Reh Annonce publiée le 12-09-2026

	NeuroPSI Salle de conference Albe-Fessard

Vendredi 09 Octobre 2026 0:00

3rd symposium: on The Connection between Physics and Metabolism In brain Functions
Barcelona Children's Hospital Sant Joan de Deu | nd the Paris Brain Institute, Drs A. Garcia-Cazorla and Fanny Mochel invite you to Barcelona a city that has, over recent decades, consolidated its position as one of Europe's most dynamic and vibrant hubs for science and health.


Previous editions have explored topics ranging from mechanotransduction the mechanical forces that shape brain development to the physics of neurotransmission, spatial mechanotranscriptomics, and the emerging field of mechanomedicine. Building on these advances, this year&'s symposium will delve deeper into the physical principles that govern brain metabolism and function, continuing to expand the frontiers of neuroscience. Plus d'infos... Tags: Neurology, Nervous system, Neurophysiology, Neuroscience Annonce publiée le 09-06-2026

	I. Cerveau et de la Moelle Exciting developments in quantum biology highlighted by an inaugural conference featuring Sonia Contera, Professor of Biological Physics at the University of Oxford.Physical approach to brain metabolism, incorporating thermodynamic principles and the emerging concept of photons as synaptic transmitters.A pioneering discipline at the intersection of biophysics, metabolism and medicine, focusing on mechanodiseases.A thought-provoking closing lecture on the relationship between metabolism and cognition.

Vendredi 09 Octobre 2026 11:30

Evolution, Development, and Function of Motor Circuits.
Lora Sweeney | Assistant Professor, Institute of Science and Technology Austria (ISTA)


Plus d'infos... Tags: Institute of Science and Technology Austria, Ista, Lora, International Seed Testing Association Annonce publiée le 04-06-2026

	NeuroPSI Salle de conference Albe-Fessard

Vendredi 09 Octobre 2026 12:00

Using frogs to uncover the evolution, development and function of motor circuits
Lora Sweeney | Assistant Professor, Institute of Science and Technology Austria (ISTA)


Plus d'infos... Tags: Frog, Ista, Organisms Annonce publiée le 15-09-2026

	NeuroPSI Salle de conference Albe-Fessard

Lundi 12 Octobre 2026 11:00

"Trnas: Architects Of Brain Development "
Juliette GODIN | Team Leader At Igbmc Institute Of Genetics And Molecular And Cellular Biology


How does a seemingly uniform pool of neural progenitors generate the extraordinary diversity of cortical neurons? Beyond transcriptional programs, our work highlights translational controland particularly tRNAsas a key regulator of corticogenesis. Using in vivo models and tRNA profiling across development, we uncover how tRNA abundance and modification shape neuronal migration, fate acquisition, and cortical maturation. These findings position tRNAs as active players in brain development and provide new insight into the molecular basis of neurodevelopmental disorders. Plus d'infos... Tags: Branches of biology, Protein biosynthesis, Biochemistry, Biology, Developmental neuroscience, RNA, Development of the cerebral cortex, Molecular biology, Development of the nervous system, Cerebral cortex, Transfer RNA, Translation Annonce publiée le 17-09-2026

	I. Cerveau et de la Moelle Please join the conference in Paris Brain Institute auditorium.

Mardi 13 Octobre 2026 0:00

Programme a venir
Journee nouveaux


Journeacute;e nouveaux entrants - Contact Nicolas Lobato-Dauzier Programme agrave; venir Plus d'infos... Annonce publiée le 07-09-2026

	Laboratoire Jean Perrin Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407

Mercredi 14 Octobre 2026 9:30

Cytoskeleton club


La prochaine reunion du cytoskeleton club aura lieu mercredi 15 octobre a l’Institut Jacques Monod : Izeta Kankadze (PhD student, Fassier/Nicol's team, Institut de la Vision) presentera «Compartmentalized Second Messenger Signals Contribute to Cytoskeletal Remodeling in Axon Guidance» Veronique MARTHIENS (Researcher, R. Basto's team, Institut Curie) presentera «Brain biomechanics governs mitotic fidelity of embryonic neural stem cells» Plus d'infos... Tags: Developmental neuroscience, Axon guidance, Cytoskeleton, Axon Annonce publiée le 03-10-2025

	Institut Jacques Monod Institut Jacques Monod Salle Francois Jacob, 15 rue Helene Brion, Paris, France

Mercredi 14 Octobre 2026 11:30

Decoding the regulation of a state of #39;suspended animation#39; in killifish
Param Priya Singh


The evolutionary success of life on Earth has been fundamentally shaped by the ability of organisms to adapt to extreme environmental conditions encountered during their lives. Understanding the regulation of these extreme adaptations can reveal conserved resilience pathways with important ramifications for survival across organisms. The African killifish provides a unique vertebrate model to study this question because its embryos naturally enter diapause-a state of suspended animation-that enables survival for years under extreme environmental stress. However, we still lack a fundamental understanding of how this protective state is coordinated across diverse organs and cell types and maintained over prolonged periods. To uncover the molecular basis of this protective state, we generated a high-resolution, temporally resolved single-cell multi-omic atlas of killifish diapause. We found that despite broad suppression of transcription, cell identity is preserved through stable cell-type-specific chromatin landscapes. Integrating single-cell chromatin accessibility with transcriptional dynamics revealed regulatory networks controlling diapause, with multiple stress-responsive AP-1 family transcription factors emerging as key regulators of the diapause gene regulatory network involved in cellular stress responses and adaptation. These findings establish diapause as a powerful vertebrate model for uncovering mechanisms of cellular resilience and long-term tissue preservation. Plus d'infos... Tags: Evolutionary developmental biology, Gene expression, Developmental biology, Physiology, Systems biology, Diapause, Chromatin, Killifish, Transcription factor, Gene regulatory network, Embryonic diapause Annonce publiée le 03-09-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie

Jeudi 15 Octobre 2026 0:00

Unraveling the molecular details of autophagy initiation
Sharon Tooze


Plus d'infos... Tags: Tooze, Titre Annonce publiée le 19-05-2026

	Institut Cochin Salle Rosalind Franklin

Jeudi 15 Octobre 2026 12:00

Title to come
Jeremie Gautheron


Plus d'infos... Tags: Jeremie, Jeremi Annonce publiée le 06-03-2026

	Centre de Recherche des Cordeliers

Vendredi 16 Octobre 2026 11:00

Seminar: mOdyssey: Revival of murine monocyte-derived dendritic cells
Marc DALOD


Invite par: Lisa Chakrabarti Marc DALOD, CIML (Centre d’Immunologie de Marseille-Luminy), Turing Center for Living Systems, CNRS, INSERM, Aix-Marseille University. A long-standing debate questions whether monocyte-derived dendritic cells (moDCs)-historically generated in vitro from monocytes using GM-CSF ± IL-4-exist ... Plus d'infos... Tags: Branches of biology, Medical specialties, Cell biology, Cytokines, Immune system, Monocyte, Dendritic cell, Centre d'immunologie de Marseille-Luminy, Granulocyte-macrophage colony-stimulating factor Annonce publiée le 12-09-2026

	Institut Pasteur Batiment Lwoff, salle Salle Retrovirus, 22-RdC-14,

Vendredi 16 Octobre 2026 11:30

Micro circuitry of the amygdala and its encoding of fear memory.
Luke R. Johnson


Plus d'infos... Tags: Amygdala, Encode, Fear, Intercalated cells of the amygdala, Fear processing in the brain Annonce publiée le 28-07-2026

	NeuroPSI Salle de conference Albe-Fessard

Lundi 19 Octobre 2026 0:00

17e edition - Biologie du Developpement


From Stem Cells to Morphogenesis Ce cours intensif combine une formation theorique et pratique afin d'explorer les concepts fondamentaux, les defis et les technologies de la biologie du developpement moderne. Le programme couvre des sujets allant de la regulation de l'expression genique et des interactions cellulaires a la formation d'un embryon multicellulaire organise. Les participants sont inities a une variete de modeles embryonnaires, incluant des organismes modeles genetiques tels que Drosophila, C. elegans, la souris et le poisson zebre, ainsi que des modeles classiques d'embryologie experimentale tels que le Xenopeet le poulet. Ces modeles sont etudies a l'aide de methodologies et de technologies de pointe. Les etudiants peuvent beneficier a la fois d'un enseignement theorique (10 jours de cours magistraux) et d'une formation experimentale (3 semaines de travaux pratiques) portant sur les aspects normaux et pathologiques du developpement. À noter que le module de cours magistraux de 10 jours peut etre suivi seul ou en combinaison avec le module de travaux pratiques. Les cours magistraux sont dispenses par des chercheurs de renommee internationale et abordent des thematiques telles que la specification et la differenciation cellulaires, la biologie des cellules souches, la morphogenese et l'organogenese, la signalisation intracellulaire, ainsi que la regulation de l'expression genique au cours du developpement. Le cycle de conferences se conclut par un congres scientifique international de 1,5 jour consacre a la morphogenese, offrant a de nombreux participants l'opportunite d'assister a leur premiere conference scientifique. OBJECTIF(S) L'objectif est de familiariser les etudiants avec les concepts recents de la Biologie du developpement en soulignant plus particulierement leur importante contribution aux domaines des cellules souches et des sciences cliniques. Differents champs de la Biologie du developpement sont presentes en relation avec les cellules souches, non seulement a travers la diversite des modeles embryonnaires mais aussi a travers les approches recentes developpees dans ces domaines (approches a grande echelle, modelisation mathematique, approches biophysiques?). Plus d informations Plus d'infos... Annonce publiée le 06-06-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Helene Martel-Massignac (BDD)

Lundi 19 Octobre 2026 11:00

Understanding complex cardiac disorders by modeling cellular crosstalk with human organoids
Prof. Hananeh FONOUDI


Invite par: Susan LIAO - Section Genomique Fonctionnelle Plus d'infos... Tags: Stem cells, Organoid, Tissue engineering, Cerebral organoid Annonce publiée le 16-09-2026

	IBENS salle Favard, IBENS 46 rue d'Ulm 75005 Paris

Mercredi 21 Octobre 2026 16:30

TBC Abstract: TBC
Laure Teysset and open slot


Laure Teysset Transgenerational Epigenetics and small RNA Biology (TErBio) Institut de Biologie Paris-Seine (IBPS), Development Adaptation and Aging (Dev2A) Sorbonne Universite, CNRS UMR8263 and INSERM U1345 Title: TBC Abstract: TBC open slot Plus d'infos... Tags: Sorbonne University, French National Centre for Scientific Research, Transgenerational Annonce publiée le 28-08-2026

	Paris RNA Club Auditorium Gallois - 45 rue d Ulm, 75005 Paris

Mercredi 21 Octobre 2026 16:30

TBC Abstract: TBC and The lncRNA BAMBOO decoys NF-YA2 transcription factor from the promoter of its root-specific targets in Arabidopsis Abstract: Plant developmental plasticity emerges from transcriptional reprogramming in response to environmental shifts, which largely depends on the activity of transcription factors (TFs). In Arabidopsis thaliana, CCAAT-binding TFs NF-YA2 and NF-YA10 (Nuclear Factor-Y A2 and A10) are post-transcriptionally regulated by microRNAs, participating in a regulatory hub controlling root architecture. Here, RNA-seq and ChIP-seq approaches served to identify NF-YA2 direct target genes involved in lateral root (LR) development, water deprivation and hormone pathways. Furthermore, we searched for NF-YA2 potential RNA partners by using RIP-seq and identified a long noncoding RNA (lncRNA) named BAMBOO after its counterpart PANDA, which interacts with mammalian NF-YA. BAMBOO is dynamically regulated during LR development and bamboomutant plants exhibit a NF-YA2-related root developmental phenotype. bamboo plants share half of its deregulated genes with the NF-YA2 regulome. In vivo, in vitro and in silico assays indicated that NF-YA2 - BAMBOO interaction depends on the DNA-binding domain and RNA sequence. When overexpressed, the lncRNA BAMBOO disturbed NF-YA2 binding to its target promoters suggesting an RNA-based competition of target recognition by NF-YA2 in chromatin. Hence, the study of lncRNAs at the organism level underscores their capacity to intricately modulate TF activity throughout targeted developmental processes, thereby fine-tuning regulatory networks.
Laure Teysset and Andana Barrios


Laure Teysset Transgenerational Epigenetics and small RNA Biology (TErBio) Institut de Biologie Paris-Seine (IBPS), Development Adaptation and Aging (Dev2A) Sorbonne Universite, CNRS UMR8263 and INSERM U1345 Title: TBC Abstract: TBC Andana Barios Postdoctoral Researcher in Herve Vaucheret's team (Epigenetique et petits ARNs) Universite Paris-Saclay, INRAE, AgroParisTech, Institut Jean-Pierre Bourgin for Plant Sciences Title: The lncRNA BAMBOO decoys NF-YA2 transcription factor from the promoter of its root-specific targets in Arabidopsis Abstract: Plant developmental plasticity emerges from transcriptional reprogramming in response to environmental shifts, which largely depends on the activity of transcription factors (TFs). In Arabidopsis thaliana, CCAAT-binding TFs NF-YA2 and NF-YA10 (Nuclear Factor-Y A2 and A10) are post-transcriptionally regulated by microRNAs, participating in a regulatory hub controlling root architecture. Here, RNA-seq and ChIP-seq approaches served to identify NF-YA2 direct target genes involved in lateral root (LR) development, water deprivation and hormone pathways. Furthermore, we searched for NF-YA2 potential RNA partners by using RIP-seq and identified a long noncoding RNA (lncRNA) named BAMBOO after its counterpart PANDA, which interacts with mammalian NF-YA. BAMBOO is dynamically regulated during LR development and bamboomutant plants exhibit a NF-YA2-related root developmental phenotype. bamboo plants share half of its deregulated genes with the NF-YA2 regulome. In vivo, in vitro and in silico assays indicated that NF-YA2 - BAMBOO interaction depends on the DNA-binding domain and RNA sequence. When overexpressed, the lncRNA BAMBOO disturbed NF-YA2 binding to its target promoters suggesting an RNA-based competition of target recognition by NF-YA2 in chromatin. Hence, the study of lncRNAs at the organism level underscores their capacity to intricately modulate TF activity throughout targeted developmental processes, thereby fine-tuning regulatory networks. Plus d'infos... Tags: Molecular biology, Gene expression, RNA, Biotechnology, Long non-coding RNA, Transcription factor, MicroRNA, Transcription, Epigenetics Annonce publiée le 29-08-2026

	Paris RNA Club Auditorium Gallois - 45 rue d Ulm, 75005 Paris

Vendredi 23 Octobre 2026 11:30

Olfaction
Claire A. de March | Institut de Chimie des Substances Naturelles ICSN, Gif-Sur-Yvette


Plus d'infos... Annonce publiée le 28-07-2026

	NeuroPSI Salle de conference Albe-Fessard

Mercredi 28 Octobre 2026 9:00

STAPA International Network Congress (SINC)


Invite par: Camille Dos Santos-Toinet The STAPA International Network Congress (SINC) is an international scientific congress dedicated to host-pathogen interactions.Organized by the Young Researcher Association of Institut Pasteur of Paris (STAPA) and in collaboration with Institut Pasteur and the ... Plus d'infos... Tags: Grand Cross of the Legion of Honour, COVID-19 pandemic in France, Pasteur Institute, Louis Pasteur, Sinc function Annonce publiée le 17-07-2026

	Institut Pasteur Batiment CIS, salle ,

Mercredi 28 Octobre 2026 9:00

STAPA International Network Congress (SINC)
Melanie Hamon


Invite par: Camille Dos Santos-Toinet The STAPA International Network Congress (SINC) is an international scientific congress dedicated to host-pathogen interactions. Organized by the Young Researcher Association of Institut Pasteur of Paris (STAPA) and in collaboration with Institut Pasteur and the ... Plus d'infos... Tags: COVID-19 pandemic in France, Pasteur Institute, Louis Pasteur, Sinc function Annonce publiée le 02-08-2026

	Institut Pasteur Batiment CIS, salle ,

Jeudi 29 Octobre 2026 9:00

Immune variability across the life course


Invite par: Darragh Duffy Thursday 29th Oct 26 \| Institut Pasteur KEYNOTE SPEAKERS ? Prof. Yasmine Belkaid President of the Institut Pasteur (Paris), Professor Yasmine Belkaid is an internationally recognized immunologist specializing in host-microbiota interactions and tissue immunity. ... Plus d'infos... Tags: Pasteur Institute, Yasmine Belkaid, Microbiology, Microbiomes, Bacteriology, Louis Pasteur, Variability, Human microbiome Annonce publiée le 24-02-2026

	Institut Pasteur Batiment: Duclaux

Vendredi 30 Octobre 2026 9:00

LabEx Milieu Interieur Annual Meeting 2026


Invite par: Darragh Duffy 30th OCTOBER 2026 \| INSTITUT PASTEUR \| FRANCE We are happy to announce the 2026 yearly meeting of Milieu Interieur LabEx Join un on the morning of the 30th of October at 9am at ... Plus d'infos... Tags: Corruption in France, Organized crime in France Annonce publiée le 22-05-2026

	Institut Pasteur Batiment: Duclaux Salle: Amphitheatre Duclaux

Vendredi 30 Octobre 2026 11:30

72 female scientists honored on the Eiffel Tower: spotlight on Denise Albe-Fessard
Philippe Vernier | Charge de mission Institut NeuroPSI


Plus d'infos... Annonce publiée le 04-06-2026

	NeuroPSI Salle de conference Albe-Fessard

Mardi 03 Novembre 2026 0:00

TBA
Olivier Cochet-Escartin


TBA Plus d'infos... Tags: Cochet, Draft:Valley Vista Elementary School Annonce publiée le 12-09-2026

	Laboratoire Jean Perrin Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407

Mardi 03 Novembre 2026 0:00

TBA
Olivier Cochet


TBA Plus d'infos... Tags: Cochet, Draft:Valley Vista Elementary School, Arthrographis kalrae Annonce publiée le 07-09-2026

	Laboratoire Jean Perrin Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407

Mardi 03 Novembre 2026 9:00

ShareFAIR days


Invite par: Frederic LEMOINE The ShareFAIR days are a two-day gathering uniting our project partners and the broader scientific community to advancing the reproducibility of neuro-vascular research. As we navigate the complexities of massive, multi-scale health data, we ... Plus d'infos... Tags: Metascience, Scientific method, Statistical reliability, Measurement, Reproducibility, Tests Annonce publiée le 17-07-2026

	Institut Pasteur Batiment Batiment Duclaux, salle Amphitheatre Duclaux,

Mardi 03 Novembre 2026 9:00

ShareFAIR and Neurovasc days


Invite par: Frederic LEMOINE The ShareFAIR days are a two-day gathering uniting our project partners and the broader scientific community to advancing the reproducibility of neuro-vascular research. As we navigate the complexities of massive, multi-scale health data, we ... Plus d'infos... Tags: Metascience, Scientific method, Statistical reliability, Measurement, Reproducibility, Tests Annonce publiée le 20-07-2026

	Institut Pasteur Batiment Batiment Duclaux, salle Amphitheatre Duclaux,

Mardi 03 Novembre 2026 9:30

Single-molecule mechanics of eukaryotic and bacterial SMC complexes
Michele Gabriele


Gene expression is tuned by enhancer-promoter interactions (EPIs) within a three-dimensional genome that is constantly in motion. Neurons take this problem to its limit: they are post-mitotic and long-lived, and they depend on regulatory elements acting across megabase distances. Consequently, mutations in chromatin regulators and alterations in genome topology cause neurodevelopmental disorders, and in other contexts as cancer. However, the principles governing how EPIs are established, maintained, and lost during differentiation remain poorly understood, largely because most measurements are static snapshots of fixed cell populations. This seminar follows a single question from disease genetics to biophysics to engineering: which chromatin-regulator genes are responsible for neurodevelopmental disorders and what the downstream phenotypic consequences of their mutations are; how those regulators physically act in single living cells, where chromatin contacts prove to be dynamic, rare, and short-lived rather than stable structures; and whether that mechanistic picture can be inverted into design, engineering EPIs and 3D genome architecture in neurons. Together, these lines of inquiry chart a multidisciplinary path from disease-gene discovery, through single-molecule biophysics, to chromatin engineering in the cells where it matters most. Plus d'infos... Tags: Branches of biology, Biology, Molecular biology, Genomics, Genetic mapping, Genome, Gene, Gene expression Annonce publiée le 09-09-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie

Jeudi 05 Novembre 2026 12:00

Title to come
Christophe Paget - Marion Salou


Plus d'infos... Tags: Salou, Paget, Salou Ibrahim Annonce publiée le 15-09-2026

	Centre de Recherche des Cordeliers

Vendredi 06 Novembre 2026 11:30

Evolution of stem cells and regeneration in animals.
Eve Gazave | Institut Jacques Monod, Paris


Plus d'infos... Tags: Senescence, Stem cells, Developmental biology, Healing, Regeneration, Institut Jacques Monod, Helen Blau, Blastema Annonce publiée le 29-07-2026

	NeuroPSI Salle de conference Albe-Fessard

Lundi 09 Novembre 2026 13:00

Allostery and brain science, a tribute to Jean-Pierre CHANGEUX


Invite par: Pierre-Jean Corringer Plus d'infos... Tags: Jean-Pierre Changeux, Neuroscientists, Allosteric regulation, Jean-Pierre, Ruth Nussinov, DehaeneChangeux model Annonce publiée le 30-04-2026

	Institut Pasteur Batiment Duclaux, salle Amphitheatre,

Mardi 10 Novembre 2026 11:00

How some bacteria swim in higher viscosities than others


Invite par: Ariane Briegel Morgan Beeby Imperial College, London, UK Abstract Many bacteria swim using helical propellers called flagella. Although most work to understand flagella have focused onEscherichia coliand closely-relatedSalmonella entericasv. Typhimurium, some bacteria are capable of swimming ... Plus d'infos... Tags: Bacteriology, Bacteria, Organelles, Domains, Gram-negative bacteria, Flagellum, Salmonella Annonce publiée le 17-08-2026

	Institut Pasteur Batiment F. Jacob, salle F. Jacob Auditorium,

Jeudi 12 Novembre 2026 11:00

Engineering synthetic gene circuits in light of host constraints: integrating stresses, controlling metabolism and creating evolutionary robustness
Alexander Darlington


Invite par: Manish Kushwaha Engineered microbial systems have a range of potential applications in healthcare, the chemicals industry and environmental science. However, host microbe constraints often lead to degraded functionality or even complete failure of genetic devices. Here we developed a unified dynamic mathematical framework of E. coli which integrates including metabolic constraints, stress-responses, ribosomal limitations and growth mediated feedback. We use this framework to design new control strategies which act to enhance both yield and growth of microbial cell factories and show that at by accounting for host constraints we can actually simplify the genetic controller designs by taking advantage of the cell's natural feedback mechanisms. We couple our host design framework with evolutionary simulations to investigate how to enhance long term performance of gene circuits. We will discuss our recent work developing similar frameworks for S. cerevisiae and P. putida. Plus d'infos... Tags: Biotechnology, Molecular genetics, Molecular biology, Pseudomonadales, Pseudomonas putida, Evolution, Genetic engineering, Microorganism, Synthetic biology Annonce publiée le 05-09-2026

	Institut Micalis Auditorium 442 - Institut Micalis

Vendredi 13 Novembre 2026 0:00

CLARA Symposium 2026 on AI for Brain Health
CLARA Days 2026.


The CLARA Symposium on AI for Brain Health brings together leading researchers and experts from neuroscience, artificial intelligence, molecular biology, clinical research, and high-performance computing to explore how AI can transform brain research and improve brain health. Hosted by the Paris Brain Institute, the symposium reflects the interdisciplinary vision of CLARA, connecting AI, data science, computational methods, and biomedical research. The programme will explore advances in molecular biology, novel approaches to phenotyping, and the potential of health data and supercomputing for brain research. Plus d'infos... Tags: Articles, Computational neuroscience, Academic disciplines, Emerging technologies, Technology, Artificial intelligence, Cybernetics, Neuroscience, Brain Annonce publiée le 22-09-2026

	I. Cerveau et de la Moelle Institut du cerveau

Vendredi 13 Novembre 2026 17:00

Title to be announced
Valentin Wyart | LNC2, ENS


The title and abstract of this talk will be announced soon. Plus d'infos... Tags: Ens, Abstract Annonce publiée le 26-08-2026

	Neural Networking Night pub Le Piano Vache - 8 Rue Laplace, 75005 Paris

Lundi 16 Novembre 2026 0:00

8eme edition - Biologie Cellulaire et Cancer


Le 8e cours «?Biologie cellulaire et cancer»?explorera comment les formes biologiques emergent a differentes echelles, de l'organisation intracellulaire jusqu'aux tissus et aux organismes entiers. Il mettra l'accent sur des processus cellulaires cles tels que la dynamique du cytosquelette et le trafic intracellulaire, et sur la maniere dont ces processus faconnent des structures cellulaires complexes. Le cours abordera egalement la formation de patterns, la morphogenese et les comportements collectifs des cellules a l'echelle des tissus, dans le contexte de la mecanobiologie et de la biologie du developpement. Plus d'infos... Annonce publiée le 07-05-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Helene Martel-Massignac (BDD)

Lundi 16 Novembre 2026 0:00

Ctrl+Epi+Edit, Engineering the Epigenome


Epigenome editing is a rapidly emerging field that has the potential to revolutionise genomic medicine by offering new ways to precisely program gene expression and treat a range of diseases. Precision control of the epigenome and gene activity is further unlocking key mechanistic insights into a wide variety of molecular and cellular processes. The potential of epigenome editing technologies for both research and therapeutic applications has thus led to widespread excitement over the last five years, in areas ranging from neurobiology, to high-throughput (epi)genomics to agriculture. As the technologies continue to emerge and the epigenome editing field begins to coalesce, we feel now is the time to bring interdisciplinary experts and leaders in the field together. This will enable, for the first time, epigenome editors and related disciplines to collectively discuss the technology, its applications and ethics, and the exciting scientific insights being generated. Such a symposium will help to accelerate progress in this field by facilitating collaborations between researchers and providing a platform for the dissemination of new discoveries and techniques. It will also help to raise broader awareness of this exciting emerging science and its potential to transform precision medicine. Time and Place The meeting will take place fromNovember 16-17atInstitut Jacques Monodin the heart of Paris, France We will have two half day sessions, and a poster session over cocktails and light bites Key Dates Abstract Submission:October 1, 2026 Registration:November 9, 2026 Invited Speakers ? Gabriella Ficz (QMUL, UK) ? Charles Gersbach (Duke University, USA) ? Jamie Hackett (EMBL Rome, Italy) ? Jake Harris (Cambridge University, UK) ?Angelo Lombardo (San Raffaele University, Italy) ? Reini Luco (Institut Curie, France) ?Mariane Rots (UMCG, Netherlands) ?Edda Schulz (MPI Berlin, Germany) ?Stefan Stricker (Helmholtz Munich, Germany) More speakers will be selected from abstracts! You can find all the informations regarding the symposium, the registration and abstract submission here Flyer of the event: here Plus d'infos... Tags: Epigenetics, Epigenome editing, Edit, Epigenome, Genome editing, Omics Annonce publiée le 10-03-2026

	Institut Jacques Monod Institut Jacques Monod Amphitheatre Buffon, 15 rue Helene Brion, Paris, France

Mardi 17 Novembre 2026 11:00

Systems and synthetic biology: constructing smart and programmable microbes and microbiota to address global problems
Tae Seok Moon


Invite par: Young-Kyoung Park, Manish Kushwaha, Olivier Borkowski The past decade has witnessed the tremendous power of systems and synthetic biology in the creation of genetic parts, devices, and systems, which helps understand complex biological systems. However, its potential for real-world applications has not been fully exploited. One of its promising applications is the construction of programmable cells that integrate multiple environmental signals and implement synthetic control over biological processes. My research interests are focused on developing microbes and microbiota that can process multiple input signals and generate user-defined outputs. Specifically, I aim to build genetic programs to control various bacterial processes such as gene expression, chemical reactions, and evolution. I will present published and unpublished results of my selected research projects by discussing the potential and challenges of systems and synthetic biology to address global problems, including plastic and agricultural waste issues, non-invasive diagnostics and disease treatment using smart probiotics and microbiota engineering, sustainable bioproduction, and biocontainment of genetically engineered microbes. Plus d'infos... Tags: Bacteriology, Microbiomes, Microbiology, Environmental microbiology, Bioinformatics, Synthetic biology, Human microbiome, Microbiota, Probiotic Annonce publiée le 04-09-2026

	Institut Micalis Auditorium 442 - Institut Micalis

Mardi 17 Novembre 2026 11:30

TBA
Dr Sophie Tronel | Neurocentre Magendie


Plus d'infos... Annonce publiée le 24-09-2026

	College de France au College de France Salle D2 - 11 place Marcelin Berthelot - 75005 Paris

Jeudi 19 Novembre 2026 12:00

Title to come
Julien Taieb


Plus d'infos... Tags: Taieb, Julien, Le Monde doit m'arriver, Taieb Fassi Fihri Annonce publiée le 15-09-2026

	Centre de Recherche des Cordeliers

Vendredi 20 Novembre 2026 11:30

Epidemiology of Allergic Conditions.
Monica Rodrigues | Erasmus PhD Student, University of Porto (Portugal)


Plus d'infos... Tags: Allergology, Allergy, Immune system, Immunology Annonce publiée le 29-07-2026

	NeuroPSI Salle de conference Albe-Fessard

Mardi 24 Novembre 2026 0:00

Paris Cytoskeleton club 2026


General information The Paris Cytoskeleton Day is a scientific one-day symposium open to all types of cytoskeletal components and all types of approaches. This year is the 6th edition. Itwill take place onTuesday, November 24, 2026. The meeting will be entirely in-person inAuditorium Buffon (Institut Jacques Monod, Paris) DEADLINES Registration and abstract submission are open : https://pcd2026.sciencesconf.org/ Abstract submission closes on 2 November Registration (45 euros) closes on 16 November KEYNOTE SPEAKERS Charlotte Aumeier(Universite de Geneve, CH) Stefan Raunser(Max Planck Institute, Dortmund, DE) INVITED SPEAKERS Alexandre Baffet(Institut Curie, Paris) Rut Carballido-Lopez(INRAE, Jouy-en-Josas) Guillaume Dumenil(Institut Pasteur, Paris) Magali Suzanne (Universite de Toulouse) SHORT TALKS Several short presentations will be selected from abstracts. POSTERS A poster session will take place during the day. Plus d'infos... Tags: European Molecular Biology Organization, Stefan Raunser, Cytoskeleton, Jouy-en-Josas, Jouy Annonce publiée le 02-09-2026

	Institut Jacques Monod Institut Jacques Monod Amphitheatre Buffon, 15 rue Helene Brion, Paris, France

Mardi 24 Novembre 2026 11:00

Engineering protein catalysts for synthetic applications


Invite par: Marcel Hollenstein Rebecca Buller Department of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Switzerland Abstract Chemical synthesis of small molecules can be profitably complemented by enzymatic catalysis. In optimal settings, enzymes can facilitate complex reactions ... Plus d'infos... Tags: Catalysis, Chemical kinetics, Biomolecules, Metabolism, Chemical synthesis, Enzyme, Protein, Synergistic catalysis, Protein engineering Annonce publiée le 24-07-2026

	Institut Pasteur Batiment Monod, salle Agnes Ullmann,

Vendredi 27 Novembre 2026 11:30

Glutamate Receptors and Excitatory Synapses.
Pierre Paoletti | IBENS Institut de Biologie de l'ENS, Paris


Plus d'infos... Tags: Excitatory synapse, Neural synapse, Glutamate, Ionotropic glutamate receptors, Neuroplasticity, Excitatory amino acid receptor ligand, GRIK3 Annonce publiée le 29-07-2026

	NeuroPSI Salle de conference Albe-Fessard

Lundi 30 Novembre 2026 9:00

International conferences Integrative Microbiome Program at Pasteur


Invite par: Benoit Chassaing To officially launch this major programme, the Pasteur Institute invites you to a two-day series of talks featuring speakers from around the world as well as from the Pasteur Institute. Further details on the ... Plus d'infos... Tags: Microbiome, Pasteur Institute, Louis Pasteur, Bioinformatics, Human Microbiome Project Annonce publiée le 09-06-2026

	Institut Pasteur Batiment: CIS Salle: CIS

Mardi 01 Decembre 2026 11:30

Cytoskeletal control of endoplasmic reticulum morphogenesis in perivascular glia
Dr Bo Gao | School of Biomedical Sciences


Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 10-06-2026

	College de France au College de France Salle D2 11 place Marcelin Berthelot - 75005 Paris

Jeudi 03 Decembre 2026 0:00

The Body in Dialogue: How the Brain Communicates with Organs


The program brings together neuroscientists, physiologists, computational biologists, and clinicians to discuss the multidirectional interactions that regulate homeostasis, emotions, and cognitionhighlighting how bodily states shape brain function. Plus d'infos... Annonce publiée le 10-08-2026

	I. Cerveau et de la Moelle The conference will open with two keynotes that will set the conceptual framework for the meeting around embodied control, movement and feedback principles in biological systems.

Vendredi 04 Decembre 2026 17:00

Holographic optogenetics for neuronal circuits interrogation
Valentina Emiliani | Institute de la Vision


The title and abstract of this talk will be announced soon. Plus d'infos... Tags: Darna, Valentina, Emiliani, Draft:Valentina Emiliani Annonce publiée le 26-08-2026

	Neural Networking Night pub Le Piano Vache - 8 Rue Laplace, 75005 Paris

Mardi 08 Decembre 2026 0:00

Paris Ultrasound Workshop: From theory to advanced experimental setup and data analysis (2 days)


This workshop aims to bridge this gap by giving a theoretical and practical training on functional ultrasound imaging (fUSi) from recognized leaders in the field. It is primarily intended to PhD students and postdocs aiming to use fUSi in their experiment, but we also welcome untrained scientists eager to discover its principle and applications. No prerequisite is necessary. Through six interactive modules, we will cover the theoretical bases of ultrafast imaging (Module #1), hands-on training on surgical design (Module #2), practical implementation of fUSi experiments in different contexts and species (Module #3), how to preprocess and analyze fUS data (Module #4). We will finally cover the specific developments of fUSi in clinical settings (Module #5) and ultrasound-based advances that offer promising avenues for neuroscience (Module #6) Plus d'infos... Tags: Acoustics, Ultrasound, Medical imaging, Magnetic resonance imaging, Medical equipment, Functional ultrasound imaging, Medical ultrasound, Gravis UltraSound Annonce publiée le 02-07-2026

	I. Cerveau et de la Moelle Institut du cerveau

Mardi 08 Decembre 2026 11:30

TBA
Dr Laurent Seugnet | Crnl


Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 21-09-2026

	College de France au College de France - Salle D2 - 11 place Marcelin Berthelot - 75005 Paris

Vendredi 11 Decembre 2026 11:30

Deciphering the molecular mechanisms of central nervous system regeneration: lessons from axolotls.
Karen Echeverri | Associate Scientist, Marine Biological Laboratory, Woods Hole, MA, USA


Plus d'infos... Tags: Branches of biology, Biology, Developmental biology, Healing, Regeneration, Senescence, Neuroregeneration, Marine Biological Laboratory Annonce publiée le 11-09-2026

	NeuroPSI Salle de conference Albe-Fessard

Mercredi 16 Decembre 2026 16:30

C and C
Olga Soutourina and Reini F. Luco


Olga Soutourina Professeur Universite Paris-Saclay - Groupe leader of the Regulatory RNAs in Clostridia team I2BC UMR 9198 Title: TBC Abstract: TBC Reini Luco Group Leader of the Chromatin & RNA splicing team Institut Curie (UMR3348-U1368) Title: TBC Abstract: TBC Plus d'infos... Tags: RNA splicing, Spliceosome, Molecular biology, Nucleic acids, Biotechnology, RNA, TBC, Reini Annonce publiée le 28-08-2026

	Paris RNA Club Auditorium Gallois - 45 rue d Ulm, 75005 Paris

Vendredi 18 Decembre 2026 10:00

New insights into regenerative programs driving cancer plasticity
Tuomas Tammela


Plasticity-the ability of cells to undergo phenotypic transitions-drives cancer progression and treatment resistance. Thus, plasticity is one of the most fundamental problems in cancer biology and one of the foremost challenges in clinical cancer management today. To date, targeting cancer plasticity has not succeeded in the clinic due to the lack of a fundamental understanding of the underlying mechanisms. Our recent published and ongoing work indicates that plasticity in lung cancer, pancreas cancer, and other carcinomas is concentrated in a minority subset of cancer cells, termed high plasticity cell states (HPCSs). Over the past several years, we have generated mouse models that allow for detection, longitudinal lineage-tracing, and ablation of the HPCS and other defined cancer cell states in lung and pancreas tumors in vivo. Using these systems, we have uncovered the HPCS cells are dedifferentiated but possess high capacity for cell state transitions, giving rise to both differentiated and advanced-stage cancer cells in situ in tumors. Longitudinal lineage tracing using secreted luciferases reveals HPCS-derived cells harbor more robust capacity for growth when compared to bulk cancer cells or another defined cancer cell state predicted to possess low plasticity. Suicide gene-mediated ablation of the HPCS in early-stage lesions abrogates tumor progression, whereas ablating HPCS cells in established tumors robustly reduces tumor burden. Leveraging these models, we have demonstrated that the HPCS gives rise to treatment-resistant cell states, whereas ablation of the HPCS abrogated resistance to chemotherapy and oncoprotein-targeted therapy. Furthermore, we show that the HPCS is a critical driver of a stromal cell circuit that drives immunosuppression, and cytoablation of the HPCS cells renders tumors vulnerable to immune attack. Interestingly, we find an HPCS-like state is ubiquitous in regenerating epithelia and carcinomas of multiple other tissues, revealing a convergence of plasticity programs in healthy and malignant epithelial tissues. In parallel studies, we have uncovered unexpected molecular drivers of this cell state, which operate system-wide in epithelial regenerative processes. These molecular mechanisms offer multiple therapeutic entry points, which may enable targeting of malignant plasticity in cancer patients. This work establishes the HPCS as a critical hub enabling reciprocal transitions between cancer cell states, including acquisition of states adapted to cancer therapies, and a critical driver of immunosuppressive tumor stroma. Targeting the HPCS may suppress cancer progression and eradicate treatment resistance. Plus d'infos... Tags: Anatomical pathology, Carcinoma, Cancer, Pancreatic cancer, Stem cells, Carcinogenesis Annonce publiée le 23-07-2026

	Institut Curie Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e

Vendredi 08 Janvier 2027 17:00

Title to be announced
Alexander Mathis | EPFL, Switzerland


The title and abstract of this talk will be announced soon. Plus d'infos... Tags: ETH Domain, Alexander Mathis, cole Polytechnique Fdrale de Lausanne, Mathis, Archizoom Annonce publiée le 26-08-2026

	Neural Networking Night pub Le Piano Vache - 8 Rue Laplace, 75005 Paris

Mardi 12 Janvier 2027 11:30

TBA
Dr Fabrice de Chaumont | Institut Pasteur


Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 21-09-2026

	College de France au College de France - Salle D2 - 11 place Marcelin Berthelot - 75005 Paris

Mardi 19 Janvier 2027 11:30

TBA
Dr Antoine Drieu | IPN


Invite par: CIRB-College de France Annonce publiée le 21-09-2026

	College de France au College de France - Salle D2 - 11 place Marcelin Berthelot - 75005 Paris

Mercredi 20 Janvier 2027 16:30

C
Helena Cruz de Carvalho and open slot


Helena Cruz de Carvalho Associate Professor (UPEC/IBENS) Ecole Normale Superieure Title: TBC Abstract: TBC open slot Plus d'infos... Tags: Carvalho, Surnames Annonce publiée le 28-08-2026

	Paris RNA Club Auditorium Gallois - 45 rue d Ulm, 75005 Paris

Mardi 02 Fevrier 2027 11:30

TBA
Dr Loic Broix | Sorbonne Universite


Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 24-09-2026

	College de France au College de France Salle D2 - 11 place Marcelin Berthelot - 75005 Paris

Mercredi 24 Fevrier 2027 16:30

and
Claudia Salinas and open slot


Claudia Salinas PhD Student in Zeynep Baharoglu's team Team EPICS - REPONSES EPITRANSCRIPTOMIQUES ET TRADUCTIONNELLES AU STRESS ANTIBACTERIEN? - Institut Pasteur Title: Abstract: open slot Title: Abstract: Plus d'infos... Tags: Grand Cross of the Legion of Honour, Louis Pasteur, Salinas, California, Salinas, Pasteur Institute, Claudia Annonce publiée le 28-08-2026

	Paris RNA Club Auditorium Gallois - 45 rue d Ulm, 75005 Paris

Jeudi 11 Mars 2027 12:00

Iron-addicted drug-tolerant persisters and ferroptosis vulnerability
Patrizia Agostinis


Drug-tolerant persisters (DTPs) are recognized as distinct cancer cell states with specific metabolic and redox adaptations, particularly involving iron-dependent vulnerabilities. DTPs also display a characteristic reliance on the lipid peroxidase GPX4 for protection from ferroptosis, an iron-driven, lipid peroxidationmediated cell death. During this lecture, we will discuss how organelle iron trafficking and metabolic pathways shape DTP&'s ferroptosis vulnerability and metastatic competence in the lymph node. Plus d'infos... Tags: Branches of biology, Biology, Cellular processes, Ferroptosis, Programmed cell death, Selenoproteins, GPX4, Cell death, Metabolism, Peroxidase, Lipid peroxidation, Organelle Annonce publiée le 15-09-2026

	Centre de Recherche des Cordeliers

Mercredi 24 Mars 2027 16:30

and
Leo Hardy and Nassim Meziane


Leo Hardy Postdoctoral Researcher in Zeynep Baharoglu's team Team EPICS - REPONSES EPITRANSCRIPTOMIQUES ET TRADUCTIONNELLES AU STRESS ANTIBACTERIEN? - Institut Pasteur Title: Abstract: Nassim Meziane PhD Student in Clement Carre and Laure Teysset Team Transgenerational Epigenetics & Small RNA Biology? - Institut de Biologie Paris Seine Title: Abstract: Plus d'infos... Tags: Transgenerational, Pasteur Institute, Louis Pasteur, Epigenetics Annonce publiée le 28-08-2026

	Paris RNA Club Auditorium Gallois - 45 rue d Ulm, 75005 Paris

Mercredi 23 Juin 2027 16:30

and
open slots


Title: Abstract: Title: Abstract: Plus d'infos... Tags: Academic publishing, Abstract, Abstraction, Draft:Abstract Wikipedia, Hadzi Annonce publiée le 28-08-2026

	Paris RNA Club Auditorium Gallois - 45 rue d Ulm, 75005 Paris

Genomes and genetics department seminar Marnix H. Medema Deciphering the Chemical Language of Microbiome Interactionsusing Computational Omics

Regulation of replication timing and chromatin architecture by nuclear membrane tethering of Rif Hisao Masai

DSCB Seminar - Dr. Fiona Watt, EMBL Heidleberg, Germany - Exploring the epidermal stem cell niche at single cell resolution

Building to understand: Enhancer-Promoter Communication in the Context of Regulatory Landscapes Christa Buecker

Inversions and the Hunt for the Genomic Targets of Selection Prof. Thomas FLATT

L'activite neuronale prenatale est requise pour la formation des compartiments du striatum Hugues CARTONNET

Developpement amp; Cancer - 16e edition

Immune cell compartmentalization and interactions in lymph nodes and spleen, with a focus on stromal fibroblasts Sanjiv A. Luther

"From Cell To Systems: Navigating The Complex Landscape Of Autism Spectrum Disorders" Gaia Novarino | Institute Of Science And Technology Austria

Modulation of socio-sexual behavior by astrocytic ?7nAChR-JAK2-STAT3 signaling in the ventral hippocampus of male mice. Tom Lakomy | NeuroPSI - Unverite Paris-Saclay

Seminaire interne: TBA

Beyond Epigenetics: Chromatin as a Metabolic Organelle Siavash Kurdistani

A TREEtise on ionotropic glutamate receptors Dr. Timothy LYNAGH

Thermodynamics of collective behavior Nikta Fakhri

Seminaire interne: Exploring the head direction system in Danionella Cerebrum / TBA Par Manon

Noradrenergic modulation of dopaminergic neurons in the dorsal raphe nucleus contributes to stress-induced reward insensitivity Dr Raffaella Tonini | Institut Italien de Tecnologie

Mecanismes moleculaires et pharmacologie des recepteurs GluD, une famille atypique de recepteurs ionotropiques au glutamate. Julia DORIA

Amplifying Funds in Infection Biology - 2nd International Symposium

A mathematical framework for understanding the timing of cell decisions: from developmental tempo to molecular mechanisms of gene regulation Ruben Perez-Carrasco

Department of Parasites and Insect Vectors Seminar : Joana Faria The architecture of disguise: how Trypanosoma brucei expresses a single variant surface antigen

Redundant microtubule abscission mechanisms buffer mechanical heterogeneities Agathe CHAIGNE

Des sifflements a la communication: vers une comprehension computationnelle des signaux acoustiques des dauphins Faadil MUSTUN

? Quand la science rencontre le patrimoine a l#039;Institut Cochin venez voir le style Pint of Science Thalie Law

Complex Networks. Thiago de Lima Prado | Department of Physics, Federal University of Parana, Curitiba, Parana, Brazil

Inferring collective dynamics from social animals to neuronal networks Xiaowen Chen | LPENS, ENS