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Bacterial infections unfold in mucus, tissues, biofilms, and confined host niches that constitute mechanically complex environments. Yet infection biology has largely focused on genetic and biochemical regulation, treating physical context as background. As a result, how mechanical constraints and host material properties shape bacterial collective behavior, virulence, and antibiotic tolerance remains poorly understood. Using an interdisciplinary approach, we study how forces regulate bacterial physiology across scales, from single cells to multicellular communities. We show that mechanical interactions can tune motility, biofilm architecture, gene expression, and antibiotic sensitivity, thereby reshaping infection outcomes. By combining engineered infection models, including organoid systems, with physical measurements and computational analysis, our work reframes infection as a process coupling biological and physical phenomena. This perspective reveals new vulnerabilities in pathogenic strategies and suggests alternative routes to control infections by targeting mechanics rather than classical molecular pathways Plus d'infos... Tags: Bacteriology, Pathogenic bacteria, Biofilm, Biological matter, Environmental microbiology, Environmental soil science, Bacteria, Infection, Pathogen, Pseudomonas aeruginosa Annonce publiée le 17-01-2026 |
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| Institut Curie Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e |
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Invite par: An?ela Davidovi? In our 15th meeting of transversal Deep Learning group (see the group page below) we are pleased to welcome Maoussi LHUILLIER-AKAKPO, PhD, a leader of recently created AIM pole (Artificial Intelligence and Mathematical modelling) ... Plus d'infos... Tags: Cybernetics, Data science, Computational neuroscience, Definition, Learning, Machine learning, Artificial intelligence, Deep learning Annonce publiée le 27-01-2026 |
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| Institut Pasteur Batiment: Lwoff RdC 14 Salle: RETROVIRUS |
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Paris post-doc seminar series. Plus d'infos... Tags: Queen of FCW, Serena Deeb, Serena, Doc Annonce publiée le 05-12-2025 |
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| Institut Cochin Salle Rosalind Franklin |
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Bladder cancer progression from non-muscle invasive (NMIBC), particularly the T1 stage, to muscle invasive disease (MIBC) represents a critical clinical transition requiring aggressive therapy due to high metastatic recurrence risk. Risk of progression of T1 tumors is mainly based on the presence of invasive tumor cells breaching the urothelial layer and invading the lamina propria. However, cellular and molecular events occurring in the tumor microenvironment (TME) that drive this progression remain poorly defined. To address this knowledge gap, we investigated the changes within the TME associated with the progression of bladder cancer. Single-cell RNA sequencing (scRNAseq) analysis of untreated NMIBC and MIBC human samples, alongside multiplexed imaging, revealed extensive cancer-associated fibroblast (CAF) remodeling as a key feature associated with disease progression. We show that activated CAFs are present in small focal patches in T1 tumors that surround a subset of invasive tumor cells. Both cell types were more strongly associated with progression into MIBC than either population alone, supporting the interaction of these two cell types to promote tumor progression. I will address the implicated cross-talk using multiplex imaging, spatial transcriptomics, scRNAseq and in vitro assays. Overall, we highlight the importance of the stromal compartment and the cross-talk between specific populations of CAFs and tumor cells that may serve as a prognostic biomarker and therapeutic target in NMIBC. Paris post-doc seminar series. Plus d'infos... Tags: Connective tissue cells, Bladder cancer, Tumor microenvironment, Cancer-associated fibroblast, Fibroblast, Metastasis, Cancer, MIBC, Draft:Sasanlimab, Oportuzumab monatox Annonce publiée le 22-01-2026 |
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| Institut Cochin Salle Rosalind Franklin |
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During early development, internal cues guide embryonic cells to acquire fate and perform morphogenesis. In nature, embryos develop within particular microenvironments, whose precise roles in regulating embryogenesis remain largely unexplored. In this study, we focus on the microbiological environment that early embryos may encounter, such as the bacteria that can prevalently infect the human uterus. Using zebrafish and mouse models of bacterial infection in early embryos, we show that epithelial cells of the embryonic surface can detect, ingest, and destroy bacteria by activating a distinct immune gene program essential for normal development. Our multi-scale analysis further reveals the cytoskeletal machinery mediating protrusion dynamics for bacterial engulfment. Remarkably, we demonstrate similar phagocytic abilities for clearing bacteria in human embryos. These findings have important implications for understanding the onset of innate immunity and the causes of human developmental failures, which underscore the role of the microenvironment in natural embryogenesis. Plus d'infos... Tags: Danio, Freshwater fish of India, Regenerative biomedicine, Stem cell research, Zebrafish, Innate immune system, Bacteria Annonce publiée le 15-01-2026 |
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| Institut Curie Centre de recherche - Paris - Amphitheatre Helene Martel-Massignac (BDD) |
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Invite par: Sebastian Baumgarten Link to your website: https://lilachsheiner.wixsite.com/sheinerlab-wtcmp Plus d'infos... Tags: Protein biosynthesis, Ribozymes, Ribosome, Ribosomal RNA, Parasitism, Mitochondrion, Toxoplasmosis Annonce publiée le 28-01-2026 |
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| Institut Pasteur Batiment Lwoff, salle Retrovirus, |
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Summary :
The CGB features Protein Simple JESS#8217;s Simple WesternTM automated system. This innovative technology from Bio-Techne performs fully automated capillary immunoassays and Western blot analyses, eliminating the complexity of traditional immunoassays such as Western blot and ELISA. This technology allows Western blots to be performed more quickly, in 3 to 5 hours depending on the method chosen, using between 3l of diluted samples. In CGB, already 99 antibodies tested for JESS, including 67 validated!!Stephanie Lerat will introduce you to this revolutionary machineAlexandre Lucas, Specialized in protein biochemistry with a focus on new technologies for automated Western and Single Cell Western, as well as the development and detection of biomarkers. Plus d'infos... Tags: Laboratory techniques, Protein methods, Molecular biology, Blot, Western blot, Immunoassay Annonce publiée le 30-01-2026 |
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| Centre de Recherche des Cordeliers |
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Invitee par l’equipe Ladoux/Mege, Jennifer Young (Assistant Professor, Biomedical Engineering Department,Principal Investigator, Mechanobiology Institute National University of Singapore) va presenter un seminaire de l’Institut Jacques Monod sur le theme : Biomaterial design for extracellular matrix mechanobiology Resume : Extracellular cues stemming from the matrix dictate a multitude of cellular functions, from motility to stem cell differentiation. Yet, the extracellular environment is inherently complex and thus hinders our understanding of specific matrix-based contributions to cellular behavior. Our work focuses specifically on the context of age-related matrix remodeling and engineering materials capable of recapitulating matrix properties in vitro at both the micro and nano length scales. This talk will highlight some of our material approaches to control cell-matrix interactions in the context of aging and mechanobiology. Our strategies ultimately aim to interrogate the cell-matrix interface using highly defined biomaterial systems that can inform future matrix-based treatment strategies. Jennifer Young was trained as a biomedical engineer at the University of California, San Diego (La Jolla, CA, USA). During her Ph.D. with Prof. Adam Engler, she studied the role of mechanics in cardiac development and created a hydrogel system capable of mimicking dynamic tissue properties in vitro. Inspired by the role of extracellular matrix (ECM) in dictating cell behavior and fate, she joined the Cellular Biophysics group of Prof. Joachim Spatz at the Max Planck Institute for Medical Research (Heidelberg, Germany) to study how nanoscale ECM cues regulate cancer cell function. She established the Soft Nano-Biomaterials Lab in 2021 at the Mechanobiology Institute and Biomedical Engineering Department, National University of Singapore where her work focuses on identifying and mimicking nano-to-microscale matrix properties and unraveling their contributions to cellular behavior. Plus d'infos... Tags: Extracellular matrix, Mechanobiology, Cell culture techniques, Biomedical engineering, Tissue engineering, Wellcome Trust Centre for Cell-Matrix Research Annonce publiée le 06-01-2026 |
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| Institut Jacques Monod Institut Jacques Monod Salle Francois Jacob, 15 rue Helene Brion, Paris, France |
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Plus d'infos... Annonce publiée le 05-01-2026 |
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| Inst. Bio. Paris Seine 7-9 quai Saint Bernard, 75005 Paris |
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Invite par: Thibaut Brunet Abstract: We study the evolution of animal body plans and nervous systems from a cell type perspective, with particular emphasis on nervous system centralization in early bilaterians. For this, we have generated whole-body single ... Plus d'infos... Tags: Education in Heidelberg, Heidelberg, Existentialists, Hannah Arendt, European Molecular Biology Laboratory, Heidelberg University Annonce publiée le 31-01-2026 |
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| Institut Pasteur Batiment Monod, salle Amphi Ullmann, |
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Plus d'infos... Annonce publiée le 02-09-2025 |
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| Inst. Bio. Paris Seine 7-9 quai Saint Bernard, 75005 Paris |
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Invite par: LEVRAUD Jean-Pierre Plus d'infos... Tags: Crystals, Diamond, Paris-Saclay University, Interfacing, Saclay, Synthetic diamond Annonce publiée le 19-01-2026 |
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| NeuroPSI Salle de conference Albe-Fessard |
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Invite par: Institut Necker Enfants Malades - Auditorium 1 Revealing cellular programs that shape successful immune activation.After completing my PhD at the Institute of Molecular Pathology (IMP) in Vienna, I pursued a short postdoctoral stay at the Centre for Genomic Regulation (CRG) in Barcelona before joining the laboratory of Michael Sixt at the Institute of Science and Technology Austria (ISTA) in Klosterneuburg. In 2017, I was awarded the NNF Young Investigator Award and funding through the Returning Experts Program of North Rhine-Westphalia, which enabled me to establish my independent research group at the University of Bonn in 2018. Since then, my lab has focused on elucidating cellular programs that govern effective immune activation, with particular emphasis on cytoskeletal dynamics. In 2025, I was appointed Full Professor at the University of Erlangen, and my group is currently transitioning from the LIMES Institute to the Medical Faculty in Erlangen. Mark your calendars and make sure to join! Plus d'infos... Tags: Institute of Science and Technology Austria, University of ErlangenNuremberg Annonce publiée le 16-01-2026 |
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| Institut Necker Enfants Malades Eva Kiermaier |
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Invite par: Dr A Joutel Idiopathic intracranial hypertension (IIH) is characterized by elevated intracranial pressure and is associated with dural venous sinus stenoses. Restoration of venous blood flow by venous stenting significantly improves brain fluid dynamics, yet the mechanisms linking venous outflow alterations to intracranial pressure elevation remain unresolved. Meningeal lymphatic vessels (MLVs) have recently been identified as regulators of brain fluid clearance, but the determinants of their maintenance and function in neurological disorders remain poorly defined. This lecture will present human and experimental evidence demonstrating that cerebral venous blood flow is required for MLV integrity and function. In IIH patients, venous sinus stenoses are associated with altered perivenous fluid distribution and brain edema. In mouse models combining venous outflow obstruction and targeted MLV depletion, impaired venous flow leads to MLV dysfunction, resulting in defective brain clearance and intracerebral hypertension. Together, these findings establish venous blood flow as an upstream regulator of meningeal lymphatic function and identify the dural venous sinuses as central regulators of brain fluid and intracerebral pressure homeostasis. Plus d'infos... Tags: Neurosurgery, Meninges, Central nervous system, Lymphatic system, Neurotrauma, Dural venous sinuses, Meningeal lymphatic vessels, Dura mater, Intracranial pressure, Idiopathic intracranial hypertension, Vein, Thrombosis Annonce publiée le 03-02-2026 |
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| Institut de Psychiatrie et Neurosciences de Paris Room D Levy, Institut de Psychiatrie et Neurosciences de Paris (IPNP) UMR 1266 INSERM - Universite Paris Cite, 102-108 Rue de la Sante - 75014 Paris |
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Plus d'infos... Tags: Ens, Carlos Costa Annonce publiée le 19-08-2025 |
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| Neural Networking Night pub Le Piano Vache - 8 Rue Laplace, 75005 Paris |
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Plus d'infos... Tags: Ens, cole normale suprieure Annonce publiée le 30-08-2025 |
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| Neural Networking Night pub Le Piano Vache - 8 Rue Laplace, 75005 Paris |
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Invite par: IBENS Neuroscience Seminar Plus d'infos... Tags: Neurological disorders, Neurodevelopmental disorder Annonce publiée le 28-01-2026 |
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| IBENS salle Dussane, 45 rue d'Ulm 75005 Paris |
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TBA Plus d'infos... Tags: Recho Omondi, Draft:God Save The Tuches, Draft:Poongodi Annonce publiée le 18-10-2025 |
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| Laboratoire Jean Perrin Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 |
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Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 06-01-2026 |
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| College de France au College de France - Salle D2 - 11 place Marcelin Berthelot - 75005 Paris |
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Join us for a focused one-day seminar at the Institut Curie in Paris, dedicated to the latest advancements in spatial analysis and transcriptomics.
Immerse yourself in cutting-edge research, methodologies, and tools, focusing on the Visium V2/HD platform. Hear from experts from key institutes and join interactive discussions.
Join us for a day of networking, learning, and unlocking new insights in spatial biology!
Make sure to reserve your seat:https://pages.10xgenomics.com/WEB-2026-02-EVENT-EMEA-INSTITUT-CURIE-SEMINAR-REGISTRATION-PAGE_LP.html Plus d'infos... Tags: Biology, Spatial biology, Spatial analysis, Insight, Curie Institute Annonce publiée le 20-12-2025 |
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| Institut Curie Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e |
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Liquid-liquid phase separation (LLPS) has emerged as a key mechanism in living cells, underlying the formation of biomolecular condensates that dynamically organize cellular matter, regulate reactions, and interact with membranes. Reproducing these features in minimal synthetic models remains a central challenge. In this talk, I will present coacervate droplets as minimal models of dynamic cellular compartments. I will first describe how light can be used as an external energy input to program coacervate phase behaviour. Using photoswitchable DNA-azobenzene systems, we achieve reversible and spatially controlled coacervation, enabling precise regulation of droplet formation and dissolution. By combining these systems with droplet-based microfluidics, we quantitatively dissect the kinetics of light-induced phase transitions and uncover non-equilibrium behaviours, such as budding and self-division. I will further illustrate how coacervates can function as reactive compartments, promoting and regulating simple chemical reactions, and how reaction-driven changes in molecular composition feed back onto phase behaviour. Finally, I will briefly discuss recent advances on coacervate-vesicle interactions, showing how condensates selectively wet phase-separated lipid membranes, a key step toward hybrid synthetic cells that integrate both membraneless and membrane-bound organization. Overall, this work shows how coacervate droplets provide minimal yet informative platforms to investigate dynamic compartmentalization principles relevant to biomolecular condensates and synthetic protocells. Plus d'infos... Tags: Origin of life, Coacervate, Colloidal chemistry, Polymer chemistry, Microfluidics, Biomolecular condensate, Protocell, Droplet-based microfluidics Annonce publiée le 31-01-2026 |
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| Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie |
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Séminaire en français, à l'invitation de Raphaël Scharfmann. Les helminthes, ces petits vers intestinaux avec lesquels nous avons co-évolué pendant plusieurs millions d’années, sont des maîtres de l’immunité. Ce sont de puissants immuno-modulateurs qui induisent une réponse Th2 contrôlée et réduisent les réponses Th1/Th17. Ils émettent également des centaines de molécules qui agissent à de multiples niveaux pour éviter leur rejet et maintenir leur hôte en bonne santé. Cette présentation vise à mieux comprendre cette thérapie qui pourrait être une piste prometteuse pour de nombreuses maladies à composante inflammatoire. Jacques Le Marois, après une formation scientifique en biologie à l’Ecole Normale Supérieure, a bifurqué ensuite vers l’entreprenariat pendant 27 ans, puis a créé en 2023 une fondation qui vise à financer des projets de recherche et d’études sur des thérapies basées sur du vivant comme la phagothérapie et l’helmintho-thérapie. Plus d'infos... Annonce publiée le 06-12-2025 |
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| Institut Cochin Salle Rosalind Franklin |
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Towards detection of enhancer and promoter activities in single cells The majority of disaese-associated genetic variants fall into intergenic, regulatory regions rather than the genes they control. Hence, the path towards identifying the cell types and developmental stages that are altered by genetic variants inevitably leads through locating and quantitatively assessing these regulatory regions and the enhancers and promoters they harbor. However, studying the activity of regulatory regions genome-wide in specific cells has been challenging. State-of-the-art approaches have low sensitivity, require extensive input material, or are limited to cell lines rather than disease-relevant tissue samples. Also, the lack of benchmarks has caused inconsistent accuracy estimates and thus an inability to compare assays and computational methods. To address these issues, we devised a new, combined approach based on the enrichment of nuclear, capped RNAs (nucCAGE) and a light-gradient boosting machine algorithm (PRIMEloci). This allowed to detect transcriptionally active regulatory regions with unmatched sensitivity and to map enhancers and promoters enriched in fine-mapped eQTLs, pathogenic GWAS variants, and CRISPRi loci. Based on the FANTOM5 enhancer atlas, we drastically expanded the landscape of known enhancers, mapped them in a cell type-specific manner and outlined inter-organ mechanisms for genetic variants influencing physiological and disease traits. In parallel, we develop experimental and computational methods to record active regulatory elements over time andin vivoon the level of genomic DNA rather than RNA via DNA adenine methylation identification (DamID). As a first step, we benchmarked all existing software dealing with DamID data. This framework allowed developing the most sensitive model for DamID data analysis and aids ongoing efforts to record enhancer and promoter activities in single cells. Together, our methods aim to link regulatory elements to their cell-type specific biological functions, facilitate variant interpretation and advance insights into gene regulation during development and disease progression. Plus d'infos... Tags: Gene expression, Enhancer, DNA adenine methyltransferase identification, Regulatory sequence, Promoter, Transcription, FANTOM, Regulation of gene expression, STARR-seq, Super-enhancer Annonce publiée le 15-01-2026 |
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| Institut Curie Centre de recherche - Paris - Amphitheatre Helene Martel-Massignac (BDD) |
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Plus d'infos... Tags: Geraldine Jones, Geraldine, Geraldine Gonzlez, Desmond Annonce publiée le 20-11-2025 |
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| Centre de Recherche des Cordeliers |
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Invite par: ROUYER Francois Plus d'infos... Annonce publiée le 28-01-2026 |
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| NeuroPSI Salle de conference Albe-Fessard |
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Invite par: Gerard Eberl Ivaylo Ivanov obtained a B.Sc. in Biotechnology and M.Sc. in Molecular Biology from Sofia University in his native Bulgaria. He obtained his Ph.D. in Cell and Molecular Biology from The University of Alabama at ... Plus d'infos... Tags: Ivaylo Ivanov, Microbiota, Immunology Annonce publiée le 12-01-2026 |
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| Institut Pasteur Batiment Metchnikoff , salle Jules Bordet Amphitheater, |
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Invite par: Auditorium 1 Presentation topic: Rat Duchenne muscular dystrophy models to decipher disease mechanisms and preclinical studies I completed my Ph.D. in molecular and cellular developmental biology at the Mount Sinai School of Medicine (New York) in the laboratory of Prof. David Sassoon, where I studied the genetic regulation of skeletal muscle development and differentiation. I then pursued postdoctoral training at the Institut Pasteur in Paris in the laboratory of Prof. Margaret Buckingham, focusing on the molecular control of skeletal muscle development and muscle stem cell biology. I was recruited by INSERM in 2000 and became an INSERM Research Director in 2006, after being awarded an INSERM AVENIR program that allowed me to establish my own independent research group at the Myology Institute (Pitie-Salpetriere, Paris). Since 2015, I am a Full Professor (PU-PH) at Universite Paris-Est Creteil and serve as Vice-Dean for Research of the Faculty of Medicine and Health. I lead the research team "Muscle Stem cells and therapies" at the IMRB (Inserm U955) and head the AFM-Telethon strategic research pole Translamuscle, coordinating large multidisciplinary programs dedicated to muscle stem cells, neuromuscular diseases, preclinical modeling and development of innovative therapies. My research focuses on the regulation of skeletal muscle stem cell during development, regeneration, and disease, with particular emphasis on PAX3/7 transcription factors, stem cell quiescence, and translational approaches for Duchenne muscular dystrophy. My work has been supported by major national and international funding agencies, and has resulted in over 140 peer-reviewed publications in leading journals. Through both my scientific and institutional roles, I am actively involved in shaping the fields of muscle biology, regenerative medicine, and translational neuromuscular research at the international level. Plus d'infos... Tags: Muscular dystrophy, Rare diseases, Duchenne muscular dystrophy, Dystrophy, Neuromuscular disease, Skeletal muscle, Draft:Yvan Torrente, Sarcospan Annonce publiée le 29-01-2026 |
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| Institut Necker Enfants Malades Frederic Relaix |
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Invite par: Anna Zhukova Real-time estimation of outbreak transmission dynamics using deep-learning-based phylodynamics Reconstructing epidemic dynamics in real-time has become crucial for effective disease management, as demonstrated by the COVID-19 pandemic. Most methods rely on epidemiological time series ... Plus d'infos... Tags: Phylogenetics, Epidemiology, Evolutionary biology, Immunology, Viral phylodynamics, Virology, Deep learning Annonce publiée le 31-01-2026 |
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| Institut Pasteur Batiment Lwoff, salle Salle RETROVIRUS (RdC 14), |
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TBA Plus d'infos... Tags: Draft:Toopy and Binoo: The Movie, Draft:Vacation with Derek Annonce publiée le 15-01-2026 |
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| Laboratoire Jean Perrin Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 |
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Maria Laura Rojas (Universite Paris Cite, INSERM U1151, CNRS UMR8253, Institut Necker Enfants Malades, Paris, France) presentera le prochain Paris postdoc seminar sur le theme : Organelle Crosstalk and Mitochondrial Renewal in Metabolic Adaptation to Shear Stress Kidney epithelial cells play a central role in maintaining body water and electrolytes balance, a function that critically depends on continuous urinary flow to maintain metabolic homeostasis and support kidney differentiation. Data from our lab have shown that urinary flow activates the autophagic machinery in kidney epithelial cells, promoting lipid droplets (LDs) catabolism and the transfer of free fatty acids to mitochondria. This process, in turn, promotes mitochondrial biogenesis and ATP production through oxidative phosphorylation. Despite these insights, how mitochondrial remodeling and inter-organelle communication are coordinated during this metabolic transition remains poorly understood. Here, we found that physiological fluid flow triggers mitochondrial membrane remodeling and turnover during shear stress adaptation, suggesting that mitochondrial renewal is essential during metabolic shift. During mitochondrial specialization, inter-organelle crosstalk occurs, particularly with LDs and the endoplasmic reticulum (ER), where tethering and lipid transfer proteins regulate mitochondrial structure and function. In this context, we identify a transient stabilization of ER-LD-mitochondria contact sites at early stages of fluid flow, required to mediate fatty acid transfer from LDs to mitochondria during shear stress, highlighting the importance of early organelle membrane mobilization in enabling cellular metabolic adaptation to mechanical cues. Plus d'infos... Tags: Cell biology, Cellular respiration, Mitochondrion, Mitochondrial biogenesis, Membrane biology, Phospholipids, Monolysocardiolipin Annonce publiée le 22-01-2026 |
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| Institut Jacques Monod Institut Jacques Monod Salle Francois Jacob, 15 rue Helene Brion, Paris, France |
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Many biological systems are very sensitive to small input signals. A tempting hypothesis is that these systems operate close to bifurcation or critical points, where the system s response exhibits a diverging susceptibility to the control parameter, and small signals are amplified into a large collective response. However, a common concern is that being close to these points requires fine-tuning of parameters, which seems impossible for noisy biological systems subject to varying environments. Based on several examples ranging from snake thermosensing and E. coli chemosensing to fly olfaction, we have investigated a feedback motif that robustly maintains these systems close to their respective critical or bifurcation point. The key ingredient is that the collective response feeds back onto the control parameter. Such a feedback scheme works well if just a single control parameter needs tuning. But robust critical behavior has also been found in high-dimensional systems like plasma membranes made up from thousands of components and in mammalian hearing where local activity of hair cells brings the whole cochlea to the edge of instability. Here we argue how these systems could find the critical manifold in the high-dimensional parameter space and why critical behavior might occur naturally in high-dimensional systems. Plus d'infos... Tags: Bifurcation theory, Bifurcation, Critical phenomena, Biological applications of bifurcation theory, Bifurcation diagram Annonce publiée le 31-01-2026 |
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| Institut Curie Centre de recherche - Paris - Amphitheatre Marie Curie |
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Plus d'infos... Annonce publiée le 12-12-2025 |
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| Institut Cochin Salle Rosalind Franklin |
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L'ADN et la diversité génétique humaine sont au cœur de nombreux débats de sociétés, y compris au-delà des questions de santé. Comme pour d'autres domaines scientifiques aujourd'hui, ces débats sont brouillés par une méconnaissance de la méthode scientifique utilisée en génétique des populations humaines pour produire des connaissances sur l'histoire de notre évolution biologique. Nous proposons dans ce séminaire de présenter comment les généticiens reconstruisent l'histoire de nos origines et de notre évolution à partir de la diversité génétique humaine telle qu'elle est observée aujourd'hui à travers le monde. Nous verrons dans ce récit que les catégories raciales n'expliquent ni la diversité génétique humaine ni l'histoire de notre évolution. Nous verrons également comment la culture est une force fondamentale de l'évolution biologique de notre espèce. Cette conférence s’adresse à tout le personnel de l’Institut Cochin sans exception et sera suivie d'un moment convivial autour d’un buffet. Au plaisir de vous y retrouver…
Laurence Bénit, Clotilde Randriamampita et Laetitia Waast
Pour le Comité Trans-Sciences Plus d'infos... Annonce publiée le 17-01-2026 |
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| Institut Cochin Salle Rosalind Franklin |
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https://shyerrodrigueslab.com/team/ Plus d'infos... Tags: Developmental biology, Anatomy, Tissue, Symmetry Annonce publiée le 27-01-2026 |
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| Institut Curie Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e |
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Invite par: Jessica Bryant Abstract : In the mosquito, Plasmodium parasites undergo a highly divergent mitosis as they form eight gametes out of a single precursor cell. Here, three rapid rounds of endomitosis are followed by a single ... Plus d'infos... Tags: Cell cycle, Malaria, Plasmodium, Actin, Mitosis, Chromosome segregation, Disease vector Annonce publiée le 28-01-2026 |
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| Institut Pasteur Batiment Lwoff, salle Retrovirus, |
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Plus d'infos... Tags: Weil, Weil der Stadt, Richard Weil Annonce publiée le 20-11-2025 |
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| Centre de Recherche des Cordeliers |
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Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 06-01-2026 |
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| College de France au College de France - Salle 2 - 11 place Marcelin Berthelot - 75005 Paris |
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Invitee par l’equipe Ribes / Nedelec, Dr Vicki Metzis, head of the Development and Transcriptional Control Group, MRC LMS, Imperial, va presenter un seminaire de l’Institut Jacques Monod sur le theme : Fine-tuning gene expression to build the body plan Resume : Vicki Metzis is a developmental biologist investigating how cells establish and maintain their identity during development. Her lab studies how gene expression dynamics are regulated by cis-regulatory elements and their impact on the variety of cell types that emerge in the developing body plan. A central focus of this work is the transcription factor CDX2, whose transient expression is essential for caudal body formation and Hoxgene patterning. In this seminar, Vicki will present the latest findings from the group revealing regulatory strategies constraining Cdx2, and the broader impact of CDX factors on the developing body plan. Plus d'infos... Tags: Transcription factors, Cdx, Homeobox protein CDX-2, Gene expression, Fine-tuning, Hox gene Annonce publiée le 07-01-2026 |
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| Institut Jacques Monod Institut Jacques Monod Salle Francois Jacob, 15 rue Helene Brion, Paris, France |
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Plus d'infos... Tags: Krysko Annonce publiée le 21-11-2025 |
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| Centre de Recherche des Cordeliers |
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Invite par: ROUYER Francois Plus d'infos... Annonce publiée le 19-01-2026 |
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| NeuroPSI Salle de conference Albe-Fessard |
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Invitee par l'equipe Palacande, Catherine H. Freudenreich (Professor of Biology, School of Arts & Sciences, Tufts University, Medford, MA, USA) presentera un seminaire de l'Institut Jacques Monod sur le theme : Overcoming natural replication barriers formed by DNA structures and the role of repositioning to the nuclear periphery Resume : All cells encounter replication barriers upon genome duplication and must overcome those barriers to survive. Many repeat sequences can form alternative DNA structures that interfere with replication and repair. This can lead to disease-causing repeat expansions. Alternatively, breaks within structure-forming repeats cause chromosome deletions and rearrangements, which are common in cancer cells undergoing replication stress. One strategy that cells use to overcome some types of replication barriers or difficult-to-repair lesions is repositioning to the nuclear periphery. I will describe research from my lab on how structure-forming DNA repeats are replicated and repaired and the role of relocation to the nuclear pore in these processes. Recent results on the mechanisms used to move damaged chromosomes to the nuclear pore and the role of this pathway in protecting genome instability will be covered. Plus d'infos... Tags: DNA replication, Mutation, Biotechnology, Chromosomes, Molecular genetics, DNA, Genome instability, Viral replication, Repeated sequence, Eukaryotic DNA replication, Origin of replication Annonce publiée le 29-01-2026 |
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| Institut Jacques Monod Institut Jacques Monod Salle Francois Jacob, 15 rue Helene Brion, Paris, France |
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Invite par: Marie-Agnes Petit The Microverse is the intricate and interconnected network of microbiomes that covers the Earth and all things on it. A key aim of our research is to understand the drivers of microbiome composition and dynamics, and understand how different biomes select for different microbes. By recycling >22k public metagenomics datasets from 140 different biomes, we charted the first map of the Microverse, providing a unique global overview of the ecological affiliations of different bacteria. Using the Microverse map as a guide, I will present examples of mechanisms that underlie the distribution of microbes and discuss their importance in microbial ecology. Plus d'infos... Tags: Environmental microbiology, Microbiomes, Microbiology, Bioinformatics, Microbiome, Metagenomics Annonce publiée le 03-12-2025 |
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| Institut Micalis Auditorium 442 - Institut Micalis |
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Proteins that assemble into condensates in solution can also condense into surface phase domains when a subset of condensate components are tethered to or interact with fluid membranes. These domains are dynamic, effectively two-dimensional, and considered prewet? because they occur well outside of the coexistence region of the condensate system alone. We show that proximity to the membrane phase transition dramatically potentiates biopolymer prewetting through a combination of theory, simulation, and experiments in well-defined reconstituted systems. When taken into cells, we show that protein prewetting at the plasma membrane inner leaflet is sensitive to perturbations of plasma membrane composition and structure. More generally, we speculate that prewetting at membranes represents a general protein assembly mechanism involved in a broad array of cell processes and sensitive to both membrane and protein properties. Plus d'infos... Tags: Membrane biology, Organelles, Biological membrane, Soft matter, Cell membrane, Cell, Sarah Veatch, Peripheral membrane proteins, Biomolecular condensate, Oxysterol-binding protein Annonce publiée le 30-01-2026 |
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| Institut Curie Centre de recherche - Paris - Amphitheatre IPGG - 6 rue Jean Calvin, Paris 5e |
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Plus d'infos... Tags: Marie-Hlne, Helene, Marie-Hlne Verlhac Annonce publiée le 21-11-2025 |
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| Centre de Recherche des Cordeliers |
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Plus d'infos... Tags: Operas, Ulisse, Flavio Manzoni, Ulisse Cantagalli Annonce publiée le 19-08-2025 |
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| Neural Networking Night pub Le Piano Vache - 8 Rue Laplace, 75005 Paris |
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TBA Plus d'infos... Tags: Husson, Draft:Toopy and Binoo: The Movie, Draft:Vacation with Derek Annonce publiée le 24-01-2026 |
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| Laboratoire Jean Perrin Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 |
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Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 30-01-2026 |
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| College de France au College de France - Salle D2 - 11 place Marcelin Berthelot - 75005 Paris |
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Chimeric antigen receptor (CAR) T cells have transformed the treatment of hematological malignancies but remain largely ineffective against solid tumors, highlighting the need for innovative strategies to enhance their activity. While recent CAR designs have focused on optimizing biochemical signaling, the biomechanical aspects of T cell activation have been widely overlooked. Yet, T cells are also regulated by the biophysical properties of their targets. Upon engagement, they form an immune synapse (IS) and sense mechanical cues through mechanosensitive receptors, which directly shape their cytotoxic function. These forces depend on target compliance and stiffness, which vary during cancer progression and may act as a “mechanical immune checkpoint” that facilitates tumor immune evasion. We hypothesize that CAR-T cells respond differently to biophysical cues compared with TCR-activated T cells, as suggested by their non-classical IS, morphological changes, and incomplete cytoskeletal remodeling. This reduced mechanosensitivity likely contributes to their limited efficacy in solid tumors. Our project aims to enhance CAR-T performance by (i) mapping how target mechanics influence activation and identifying key mechanosensitive proteins, and (ii) engineering CARs with enhanced force sensing. By integrating biomechanics into the CAR-T engineering toolkit, we aim to open new avenues for overcoming the barriers that currently limit their effectiveness against solid tumors. Paris postdoc seminar series Plus d'infos... Annonce publiée le 12-12-2025 |
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| Institut Cochin Salle Rosalind Franklin |
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Microbial communities are important for health, industry and the environment. However, they contain many species and are difficult to understand and predict . Using a combination of theory and experiment, we study what it takes for bacteria to succeed in diverse communities and develop strategies to improve gut health. Plus d'infos... Tags: Microbiomes, Bacteriology, Environmental microbiology, Microbiology, Microbiome, Kevin Foster, Human microbiome, Bacteria, Microorganism, Pharmacomicrobiomics, Developmental symbiosis Annonce publiée le 24-01-2026 |
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| Institut Curie Centre de recherche - Paris - Amphitheatre Helene Martel-Massignac (BDD) |
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Plus d'infos... Annonce publiée le 05-01-2026 |
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| Inst. Bio. Paris Seine 7-9 quai Saint Bernard, 75005 Paris |
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Invite par: Cecile Apert Women's health, Women in Health March 17th 2026 ? Institut Pasteur, Paris, France Registration and Poster application Fill the form The Institut Pasteur is pleased to invite you to the symposium Women's Health, Women ... Plus d'infos... Tags: Grand Cross of the Legion of Honour, Louis Pasteur, Pasteur Institute, Pasteur station, Pasteur Network Annonce publiée le 23-01-2026 |
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| Institut Pasteur Batiment: CIS Salle: CIS |
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Invite par: Philipp Deist FAN LIU Leibniz-Forschungsinstitut fur Molekulare Pharmakologie (FMP) External attendees wishing to participate in the seminar are required to contact the following email address dbsc@pasteur.fr in order to obtain access to the Institut Pasteur premises ABSTRACT ... Plus d'infos... Tags: COVID-19 pandemic in France, Pasteur Institute, Louis Pasteur, Structure, Leibniz-Forschungsinstitut fr Molekulare Pharmakologie Annonce publiée le 22-01-2026 |
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| Institut Pasteur Batiment F. Jacob Auditorium, salle , |
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Plus d'infos... Tags: Feminine given names, Patrizia Annonce publiée le 05-12-2025 |
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| Centre de Recherche des Cordeliers |
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TBA Plus d'infos... Tags: Bastien, Renaud, Draft:Toopy and Binoo: The Movie, Draft:Vacation with Derek Annonce publiée le 17-01-2026 |
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| Laboratoire Jean Perrin Laboratoire Jean Perrin - Campus Jussieu - T 22-32- 4e et. - P407 |
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Invite par: Cirb Plus d'infos... Annonce publiée le 15-10-2025 |
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| College de France au College de France - Salle D2 11 place Marcelin Berthelot - 75005 Paris |
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Vers une comprehension quantitative de la dynamique nucleaire au cours du developpement et des maladies Les objectifs de ce cours sont de fournir un apercu des mecanismes epigenetiques et de leurs liens avec la chromatine. Les differentes fonctions du noyau impliquant le genome et son organisation seront discutees en insistant sur les limites technologiques et les nouvelles approches experimentales developpees. Les liens entre la perte des fonctions du noyau et le developpement de pathologies humaines seront presentes. Cette annee ce cours abordera plus amplement les aspects physiologiques et pathologiques de l'epigenetique, en lien avec le metabolisme et la determination et maintien de l'identite cellulaire. Le succes de ce cours repose sur une forte contribution des participants qui doivent assister de facon tres proactive a l'ensemble des activites organises, tels que les sessions de presentations de posters, les analyses d'articles (Journal Club), et les ateliers. (voir section Travail personnel et le Programme pour plus d information). Une session speciale sera aussi dediee a aux presentations et echanges avec 1-2 alumni du cours qui ont poursuivi leur carriere dans le domaine de l'epigenetique. Plus d'infos... Annonce publiée le 11-11-2025 |
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| Institut Curie Centre de recherche - Paris - Amphitheatre Helene Martel-Massignac (BDD) |
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The second meeting of theFBI Mechanobiology WGwill take place on the26 and 27 of March 2026at theInstitut de Biologie Paris Seineand theInstitut Jacques Monodin Paris. The programme will include aseminar by Kate Miroshnikova(NIDDK/NIH, Bethesda USA and Max Planck Institute for Molecular Biomedicine, Munster, Germany),presentations by participantsandpractical mechanobiology workshops(a choice of 4 workshops from a dozen:optical tweezers, micro/nano-fabrication, microfluidics, AFM, micropipette aspiration, mechanical confinement, force measurements, etc?). Preliminary program: Day 1 - 26/03/2026, Paris 5e(IBPS / Curie / IPGG) Morning: scientific presentations, small group discussion Afternoon : 2 sessions of practical workshops on real set-ups in participating labs (Paris 5e) Day 2 - 27/03/2026, Paris 13e(IJM / MSC / LIED) Morning: scientific presentations, poster session Afternoon : 2 sessions of practical workshops on real set-ups in participating labs (Paris 13e) Infos & registration: Registration is free,but places arelimitedandprioritywill be given to contributors whoseabstracts have been selected. Restration link : here Plus d'infos... Tags: Institut Pierre-Gilles de Gennes, Paris Sciences et Lettres University, Bioimaging, IJM, Institut Jacques Monod Annonce publiée le 28-11-2025 |
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| Institut Jacques Monod Institut Jacques Monod Amphitheatre Buffon, 15 rue Helene Brion, Paris, France |
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Plus d'infos... Annonce publiée le 12-12-2025 |
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| Centre de Recherche des Cordeliers |
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Invite par: BOUVIER Guy Plus d'infos... Tags: Neuroplasticity, Synaptic plasticity, Activity-dependent plasticity, Draft:Jeffrey C. Magee Annonce publiée le 28-01-2026 |
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| NeuroPSI Salle de conference Albe-Fessard |
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Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 15-12-2025 |
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| College de France au College de France - Salle D2 - 11 place Marcelin Berthelot - 75005 Paris |
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Plus d'infos... Tags: Yves, Curling at the 2026 Winter Olympics, United States Olympic curling trials Annonce publiée le 22-01-2026 |
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| Centre de Recherche des Cordeliers |
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Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 15-10-2025 |
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| College de France au College de France - Salle D2 11 place Marcelin Berthelot - 75005 Paris |
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Ce cours etudiera le spectre complet de la biologie du genome, de l'organisation et de l'imagerie de la chromatine a l'epigenetique, a l'ADN mobile et a la dynamique evolutive. Au cours de six sessions ciblees, des experts de renommee internationale presenteront leurs dernieres decouvertes liees a l'identification et a la caracterisation fonctionnelle du genome non codant et discuteront de nouveaux concepts de regulation et d'evolution du genome, en mettant l'accent sur les outils experimentaux et informatiques. Les sessions thematiques comprendront des approches unicellulaires et translationnelles de pointe pour demeler la plasticite et l'heterogeneite cellulaires, interroger la regulation des genes et suivre l'evolution du genome dans la physiologie et la maladie. Ce cours offrira aux jeunes etudiants et aux chercheurs l'occasion d'elargir leurs connaissances et de discuter de leurs travaux avec une communaute scientifique internationale dans un environnement chaleureux et stimulant a l'Institut Curie a Paris. Plus d'infos... Annonce publiée le 23-10-2025 |
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| Institut Curie Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e |
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Intermittent hyperglycemia, characterized by fluctuations in blood glucose levels, has been proposed as a stronger driver of vascular damage than sustained hyperglycemia. This project aims to investigate its role in the development of atherosclerosis. We will use low-density lipoprotein receptor-deficient (Ldlr-/-) mice, a well-established model of atherosclerosis, maintained on a cholesterol-enriched diet to promote lesion formation. To mimic clinical glycemic variability, mice will receive drinking water supplemented with fructose and glucose either continuously or discontinuously, generating sustained versus intermittent hyperglycemia, respectively. We will monitor metabolic parameters, inflammatory markers, and gut microbiota composition to assess systemic and intestinal responses. Atherosclerotic burden will be quantified by histological and morphometric analyses of the aortic root and en face preparations of the aorta.
We hypothesize that intermittent hyperglycemia will exacerbate systemic inflammation and accelerate atherosclerotic lesion development compared with continuous exposure, potentially through enhanced oxidative stress and microbiota dysbiosis. This study will provide mechanistic insights into how glycemic fluctuations influence cardiovascular risk, with implications for the management of diabetic patients. Paris postdoc seminar series Plus d'infos... Annonce publiée le 12-12-2025 |
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| Institut Cochin Salle Rosalind Franklin |
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Plus d'infos... Tags: Otome games, Video games developed in Japan, Shjo manga, Angelique, Anglique, Angelique Luminarise, Koi suru Tenshi Angelique Annonce publiée le 23-01-2026 |
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| Centre de Recherche des Cordeliers |
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Invite par: Francois Bontems ReCombinaisons se veut un espace de rencontre et de discussion entre chercheuses et chercheurs (biologie-sante, sciences humaines et sociales, philosophie), autrices, auteurs et artistes de science-fiction, et public le plus large possible, pour reflechir ... Plus d'infos... Annonce publiée le 26-09-2025 |
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| Institut Pasteur Batiment: CIS Salle: Auditorium |
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Plus d'infos... Tags: Ranft, Ens Annonce publiée le 19-08-2025 |
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| Neural Networking Night pub Le Piano Vache - 8 Rue Laplace, 75005 Paris |
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Invite par: CIRB-College de France Plus d'infos... Tags: Bendor, University College London, Wellcome Trust, Ben-Dor Annonce publiée le 27-11-2025 |
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| College de France au College de France - Salle D2 - 11 place Marcelin Berthelot - 75005 Paris |
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Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 06-01-2026 |
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| College de France au College de France Amphi Delmas-Marty - 11 place Marcelin Berthelot - 75005 Paris |
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Invite par: Benoit Marteyn Shigella was the leading cause of diarrheal disease during World War One; and more than 100 years later, it continues to cause approximately 200 million cases and 216,000 deaths per year around the globe. Shigella is a ... Plus d'infos... Tags: Waterborne diseases, Intestinal infectious diseases, Enterobacteriaceae, Shigella, Diarrhea, Shigellosis, Shigella sonnei Annonce publiée le 20-01-2026 |
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| Institut Pasteur Batiment CIS , salle , |
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Plus d'infos... Tags: Saclay, Paris-Saclay University Annonce publiée le 19-08-2025 |
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| Neural Networking Night pub Le Piano Vache - 8 Rue Laplace, 75005 Paris |
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Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 15-12-2025 |
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| College de France au College de France - Salle D2 - 11 place Marcelin Berthelot - 75005 Paris |
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We are happy to announce theopening of registrations for the 16th edition of the French 3R meetingReplication, Recombination, Repair?! The meeting will take place fromMay 18 to 21, 2026, at the Belambra Club Presqu'ile du Ponant,La Grande Motte near Montpellier, France. Please visit the meeting website:https://www.2026.3r-meeting.fr/ Registrations will be open fromJanuary 12, to March 23, 2026. Deadline for abstract submission: 2nd of March 2026 Early birdregistrations fees are proposed until2nd of March 2026as following (tax-free): PhD students and postdocs (shared accommodation): 400 € Researchers, engineers, permanent staff (shared accommodation): 480 € Researchers, engineers, permanent staff (single accommodation): 550 € Sponsors and non-academic participants (without accommodation): 300 € Single accommodation is available in limited numbers and will be allocated on a first-come, first-served basis. Shared accommodation consists of two separate bedrooms and one bathroom. Full pricesafter the 2nd of March 2026 as following: PhD students and postdocs (shared accommodation): 480 € Researchers, engineers, permanent staff (shared accommodation): 560 € Researchers, engineers, permanent staff (single accommodation): 630 € Sponsors and non-academic participants (without accommodation): 300 € Please share this message with anyone who might be interested. We hope to see you all at the meeting! The organizing committee Flyer Plus d'infos... Tags: Academic administration, Postdoctoral researcher Annonce publiée le 29-01-2026 |
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| Institut Jacques Monod Presqu'ile du Ponant, France, Rue Saint-Louis,, La Grande-Motte, France |
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Plus d'infos... Tags: Mauri, Claudia, Barrier to the North, He Was Called Holy Ghost Annonce publiée le 27-01-2026 |
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| Centre de Recherche des Cordeliers |
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Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 30-01-2026 |
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| College de France au College de France - Salle 2 - 11 place Marcelin Berthelot - 75005 Paris |
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Plus d'infos... Tags: Bregaglia, ItalySwitzerland border, Pizz Gallagiun Annonce publiée le 23-09-2025 |
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| Inst. Bio. Paris Seine 7-9 quai Saint Bernard, 75005 Paris |
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Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 15-12-2025 |
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| College de France au College de France - Salle D2 - 11 place Marcelin Berthelot - 75005 Paris |
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Cystic fibrosis is a genetic disease characterized by a dehydration of airway mucus leading to increased viscosity, significant inflammation, lung infections and tissue damage. Because progression of the disease cannot be solely explained by genetic factors, some studies are now interested in the intrinsic and extrinsic factors that exacerbate CF symptoms. Among those factors, reduced levels of specialized proresolving lipid mediators (SPM) in CF airway and exposure to air pollution have been reported. In addition, some pollutants have been shown to impact SPM biosynthesis. However, the possible role of air pollution on SPM metabolism dysregulation in CF and the role of SPM in protecting CF airways from air pollution induced damages have not been explored.
In our project, we use Scnn1b transgenic mice as a model for CF airway disease. In collaboration with the LISA (Interuniversity Laboratory of Atmospheric Systems / Laboratoire Interuniversitaire des Systèmes Atmosphériques), we study how exposure to a polluted atmosphere can impact the SPM and, more generally, the resolution of inflammation in the airway. Paris postdoc seminar series Plus d'infos... Tags: Lung disorders, Channelopathies, Cystic fibrosis, Fibrosis Annonce publiée le 18-12-2025 |
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| Institut Cochin Salle Rosalind Franklin |
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Invite par: Anna-Bella Failloux Grand challenges in vector-borne diseases Controlling vectors in the context of climate and environmental changes June 5th 2026 ? Institut Pasteur, Paris, France Registration is free but mandatory Registration form As part of the ... Plus d'infos... Tags: Infectious diseases, Epidemiology, Vector calculus, Disease transmission, Disease vector, Parasitology, Vector, Euclidean vector, Climate change and infectious diseases Annonce publiée le 07-11-2025 |
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| Institut Pasteur Batiment: Duclaux Salle: Amphitheatre Duclaux |
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Plus d'infos... Tags: Fricker, Desdemona Annonce publiée le 19-08-2025 |
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| Neural Networking Night pub Le Piano Vache - 8 Rue Laplace, 75005 Paris |
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Invite par: CIRB-College de France Plus d'infos... Annonce publiée le 06-01-2026 |
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| College de France au College de France - Salle D2 - 11 place Marcelin Berthelot - 75005 Paris |
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Cette journee sera consacree aux recherches fondamentales et appliquees dans le domaine en pleine expansion des interactions entre cellules stromales (en particulier les fibroblastes et les cellules endotheliales) et cellules immunitaires au sein du microenvironnement tumoral (TME). Au cours de la derniere decennie, le stroma tumoral est devenu une cible therapeutique prometteuse dans le cancer, les fibroblastes associes au cancer (CAF) jouant un role cle dans la structuration du TME, la regulation de la croissance tumorale, l'evasion immunitaire et la resistance aux chimiotherapies et immunotherapies. Le nombre d'experts en France travaillant dans ce domaine ne cesse de croitre, et nous ressentons le besoin d'organiser un symposium qui reunisse des chercheurs experimentes et des debutants afin de favoriser la creation d'une communaute. Inspire par les initiatives fructueuses des dernieres decennies autour de la recherche sur les lymphocytes et les cellules myeloides, ce symposium vise a aider un cercle pluridisciplinaire d'experts interesses par les fibroblastes du TME a etablir des consensus sur les pratiques experimentales, proposer des nomenclatures unifiees, partager des resultats et echanger des modeles. L'objectif de ce symposium est de renforcer les collaborations naissantes et d'accroitre la visibilite internationale de l'Institut Curie et de la France dans le domaine de l'etude du stroma dans le cancer. Il s'adresse a des personnes disposant d'au moins des connaissances de base en biologie ou immunologie (niveau recommande : Master). Cet evenement sera egalement une opportunite pour faire progresser la recherche translationnelle et le developpement de traitements anticancereux ciblant specifiquement les composants stromaux. Le symposium se tiendra le mardi 23 juin 2026, de 8h30 a 20h, dans l'Amphitheatre Constant Burg (12 rue Lhomond, 75005 Paris, niveau -1), le plus spacieux et confortable de l'Institut Curie, avec ses 196 places. Nous esperons accueillir entre 120 et 150 participants. Les scientifiques que nous avons invites et qui ont confirme leur participation pour presenter leurs projets et leurs resultats les plus recents dans le domaine du stroma, de l'immunite et du cancer, sont listes ci-dessous par ordre alphabetique : CONFERENCIERS PRINCIPAUX (KEYNOTE SPEAKERS) Alexandra Naba - Etats-Unis Shannon Turley - Etats-Unis INTERVENANTS (SPEAKERS) Corinne Bousquet - France Cedric Gaggioli - France Fatima Mechta-Grigoriou - France Lucie Peduto - France Helene Salmon - France Karine Tarte - France Danijela Vignjevic - France En complement, trois jeunes postdocs/chercheurs (1 venant de l'UE, 1 hors Paris et 1 parisien) seront selectionnes pour des presentations courtes (10 minutes + 5 minutes de questions). La selection se fera sur la base des resumes des posters soumis lors de l'inscription. Nous veillerons autant que possible a respecter la parite hommes-femmes parmi les intervenants. L'inscription au symposium sera gratuite mais obligatoire. Nous diffuserons largement l'annonce afin de maximiser la visibilite et d'attirer des chercheurs, etudiants, medecins et ingenieurs internationaux, qui devront prendre en charge leurs frais de voyage et d'hebergement. Une session de posters accompagnee d'un « vin et fromage » sera organisee en fin de symposium, mais les posters pourront etre affiches des le matin a proximite de l'espace cafe/dejeuner pour favoriser les echanges tout au long des pauses. L'IHU Cancers de femmes de l'Institut Curie sponsorise cet evenement, dont la thematique correspond a l'un de ses axes de recherche. Plus d'infos... Annonce publiée le 08-11-2025 |
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| Institut Curie Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e |
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Cet evenement d'une journee sera consacre a la recherche fondamentale et appliquee dans le domaine en pleine expansion des interactions entre cellules stromales (notamment fibroblastes et cellules endotheliales) et cellules immunitaires au sein du microenvironnement tumoral (TME). Au cours de la derniere decennie, le stroma tumoral est apparu comme une cible therapeutique prometteuse dans le cancer, les fibroblastes associes au cancer (CAF) jouant un role cle dans la structuration du TME, la regulation de la croissance tumorale, la promotion de l'evasion immunitaire et la contribution a la resistance auxchimiotherapie et auximmunotherapies. Les scientifiques que nous avons invites et qui ont confirme leur participation pour presenter leurs projets et leurs resultats les plus recents dans le domaine du stroma, de l'immunite et du cancer sont listes ci-dessous par ordre alphabetique : CONFERENCIERS INVITES (KEYNOTE) Alexandra Naba - USA Shannon Turley - USA INTERVENANTS Corinne Bousquet - France Cedric Gaggioli - France Fatima Mechta-Grigoriou - France Lucie Peduto - France Helene Salmon - France Karine Tarte - France Danijela Vignjevic - France En plus de ces intervenants, trois jeunes post-doctorants/chercheurs (1 de l'UE, 1 hors Paris et 1 de Paris) seront selectionnes pour des presentations courtes (10 minutes + 5 minutes de questions). La selection se fera sur la base des resumes de posters soumis lors de l'inscription. Nous veillerons a assurer un equilibre hommes-femmes parmi les intervenants. L'inscription au symposium sera gratuite mais obligatoire. Nous diffuserons largement l'annonce du symposium afin de maximiser sa visibilite et d'attirer des chercheurs, etudiants, medecins et ingenieurs internationaux, qui prendront en charge leurs frais de deplacement et d'hebergement. Une session poster accompagnee de vin et fromage se tiendra a la fin du symposium, mais les posters seront affiches des le matin pres de la zone cafe/dejeuner pour encourager les echanges tout au long des pauses. L'IHU Cancers des Femmes de l'Institut Curie sponsorise l'evenement, car le theme s'inscrit dans l'une de ses priorites de recherche. Inscription gratuite mais obligatoire avant le 10 juin 2026:https://forms.office.com/e/pMdqmCLZcP Plus d'infos... Annonce publiée le 14-11-2025 |
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| Institut Curie Centre de recherche - Paris - Amphitheatre Constant-Burg - 12 rue Lhomond, Paris 5e |